Skip to main content

Research Repository

Advanced Search

Potential of using visual imagery to revolutionise measurement of emotional health (2020)
Journal Article
Herring, A. M. R., Craven, M. P., Mughal, F., Rawsthorne, M., Rees, K., Walker, L., & Wolpert, M. (2020). Potential of using visual imagery to revolutionise measurement of emotional health. Archives of Disease in Childhood, 105(7), 690-693. https://doi.org/10.1136/archdischild-2019-317758

Appropriate measurement of emotional health by all those working with children and young people is an increasing focus for professional practice. Most of the tools used for assessment or self-assessment of emotional health were designed in the mid-20... Read More about Potential of using visual imagery to revolutionise measurement of emotional health.

Network analysis of human muscle adaptation to aging and contraction (2020)
Journal Article
Etheridge, T., Willis, C., Atherton, P., Ames, R., Szewczyk, N., Deane, C., Kadi, F., Phillips, B., Smith, K., Boereboom, C., Wilkinson, D., Abdulla, H., Williams, J., Bukhari, S., & Lund, J. (2020). Network analysis of human muscle adaptation to aging and contraction. Aging, 12(1), 740-755. https://doi.org/10.18632/aging.102653

Resistance exercise (RE) remains a primary approach for minimising aging muscle decline. Understanding muscle adaptation to individual contractile components of RE (eccentric, concentric) might optimise RE-based intervention strategies. Herein, we em... Read More about Network analysis of human muscle adaptation to aging and contraction.

A randomized, controlled, double-blind crossover study on the effects of isoeffective and isovolumetric intravenous crystalloid and gelatin on blood volume, and renal and cardiac hemodynamics (2019)
Journal Article
Bradley, C. R., Bragg, D. D., Cox, E. F., El-Sharkawy, A. M., Buchanan, C. E., Chowdhury, A. H., Macdonald, I. A., Francis, S. T., & Lobo, D. N. (2020). A randomized, controlled, double-blind crossover study on the effects of isoeffective and isovolumetric intravenous crystalloid and gelatin on blood volume, and renal and cardiac hemodynamics. Clinical Nutrition, 39(7), 2070-2079. https://doi.org/10.1016/j.clnu.2019.09.011

Background & aims
Blood volume expanding properties of colloids are superior to crystalloids. In addition to oncotic/osmotic properties, the electrolyte composition of infusions may have important effects on visceral perfusion, with infusions contai... Read More about A randomized, controlled, double-blind crossover study on the effects of isoeffective and isovolumetric intravenous crystalloid and gelatin on blood volume, and renal and cardiac hemodynamics.

PAIN AND FATIGUE IN EARLY RHEUMATOID ARTHRITIS - A CROSS-SECTIONAL STUDY (2019)
Presentation / Conference Contribution
Ifesemen, O., McWilliams, D., Young, A., Kiely, P., & Walsh, D. (2019, September). PAIN AND FATIGUE IN EARLY RHEUMATOID ARTHRITIS - A CROSS-SECTIONAL STUDY. Poster presented at 11th Congress of the European Pain Federation EFIC, Valencia, Spain

O.S. Ifesemen, D.F. McWilliams, A. Young, P.D.W. Kiely, D.A. Walsh
Background and Aims

Pain and fatigue are prevalent and impair quality of life in people with Rheumatoid Arthritis (RA). They might be caused by multiple and overlapping mechanis... Read More about PAIN AND FATIGUE IN EARLY RHEUMATOID ARTHRITIS - A CROSS-SECTIONAL STUDY.

Automated virtual reality (VR) cognitive therapy for patients with psychosis: study protocol for a single-blind parallel group randomised controlled trial (gameChange) (2019)
Journal Article
Freeman, D., Yu, L.-M., Kabir, T., Martin, J., Craven, M., Leal, J., Lambe, S., Brown, S., Morrison, A., Chapman, K., Dudley, R., O'Regan, E., Rovira, A., Goodsell, A., Rosebrock, L., Bergin, A., Cryer, T. L., Robotham, D., Andleeb, H., Geddes, J. R., …Waite, F. (2019). Automated virtual reality (VR) cognitive therapy for patients with psychosis: study protocol for a single-blind parallel group randomised controlled trial (gameChange). BMJ Open, 9(8), e031606. https://doi.org/10.1136/bmjopen-2019-031606

Introduction Many patients with psychosis experience everyday social situations as anxiety-provoking. The fears can arise, for example, from paranoia, hallucinations, social anxiety or negative-self beliefs. The fears lead patients to withdraw from a... Read More about Automated virtual reality (VR) cognitive therapy for patients with psychosis: study protocol for a single-blind parallel group randomised controlled trial (gameChange).

Increased fasting small bowel water content in untreated coeliac disease and scleroderma as assessed by MRI (2019)
Journal Article
Lam, C., Sanders, D., Lanyon, P., Garsed, K., Foley, S., & Pritchard, S. (2019). Increased fasting small bowel water content in untreated coeliac disease and scleroderma as assessed by MRI. United European Gastroenterology Journal, 7(10), 1353-1360. https://doi.org/10.1177/2050640619860372

Background and aims: The regular overnight migrating motor complex (MMC) ensures that the normal fasting small bowel water content (SBWC) is minimised. We have applied our recently validated non-invasive magnetic resonance technique to assess SBWC in... Read More about Increased fasting small bowel water content in untreated coeliac disease and scleroderma as assessed by MRI.

Joint modelling of diffusion MRI and microscopy (2019)
Journal Article
Howard, A. F., Mollink, J., Kleinnijenhuis, M., Pallebage-Gamarallage, M., Bastiani, M., Cottaar, M., Miller, K. L., & Jbabdi, S. (2019). Joint modelling of diffusion MRI and microscopy. NeuroImage, 201, Article 116014. https://doi.org/10.1016/j.neuroimage.2019.116014

The combination of diffusion MRI (dMRI) with microscopy provides unique opportunities to study microstructural features of tissue, particularly when acquired in the same sample. Microscopy is frequently used to validate dMRI microstructure models, ad... Read More about Joint modelling of diffusion MRI and microscopy.

Increased fasting small-bowel water content in untreated coeliac disease and scleroderma as assessed by magnetic resonance imaging (2019)
Journal Article
Lam, C., Sanders, D., Lanyon, P., Garsed, K., Foley, S., Pritchard, S., Marciani, L., Hoad, C. L., Costigan, C., Gowland, P., & Spiller, R. (2019). Increased fasting small-bowel water content in untreated coeliac disease and scleroderma as assessed by magnetic resonance imaging. United European Gastroenterology Journal, 7(10), 1353-1360. https://doi.org/10.1177/2050640619860372

Background and aims: The regular overnight migrating motor complex (MMC) ensures that the normal fasting small bowel water content (SBWC) is minimised. We have applied our recently validated non-invasive magnetic resonance technique to assess SBWC... Read More about Increased fasting small-bowel water content in untreated coeliac disease and scleroderma as assessed by magnetic resonance imaging.

Determining the sample size for future trials of hearing instruments for unilaterally deaf adults: an application of network meta-analysis (2019)
Journal Article
Gaunt, A. C., & Kitterick, P. T. (2019). Determining the sample size for future trials of hearing instruments for unilaterally deaf adults: an application of network meta-analysis. Otology and Neurotology, 40(4), e342–e348. https://doi.org/10.1097/MAO.0000000000002186

Objective: Previous trials have compared the efficacy of hearing instruments to no intervention in adults with single- sided deafness (SSD) or the relative efficacy of different instruments. Network meta-analysis (NMA) was used to refine estimates of... Read More about Determining the sample size for future trials of hearing instruments for unilaterally deaf adults: an application of network meta-analysis.

Content validity and readability of patient-reported questionnaire instruments of hearing disability (2019)
Journal Article
Manchaiah, V., Granberg, S., Grover, V., Saunders, G., & Hall, D. (2019). Content validity and readability of patient-reported questionnaire instruments of hearing disability. International Journal of Audiology, 58(9), 565-575. https://doi.org/10.1080/14992027.2019.1602738

Objective: The current study evaluates the content validity (i.e., domains assessed) and readability levels of patient-reported questionnaire instruments using internationally recognized
procedures and tools.

Design: A review of the literature to... Read More about Content validity and readability of patient-reported questionnaire instruments of hearing disability.

The Cost-Effectiveness of Bimodal Stimulation Compared to Unilateral and Bilateral Cochlear Implant Use in Adults with Bilateral Severe to Profound Deafness (2019)
Journal Article
Theriou, C., Fielden, C. A., & Kitterick, P. T. (2019). The Cost-Effectiveness of Bimodal Stimulation Compared to Unilateral and Bilateral Cochlear Implant Use in Adults with Bilateral Severe to Profound Deafness. Ear and Hearing, 40(6), 1425–1436. https://doi.org/10.1097/AUD.0000000000000727

Objectives: An increasing number of severe-profoundly deaf adult unilateral cochlear implant (CI) users receive bimodal stimulation; that is, they use a conventional acoustic hearing aid (HA) in their non-implanted ear. The combination of electric an... Read More about The Cost-Effectiveness of Bimodal Stimulation Compared to Unilateral and Bilateral Cochlear Implant Use in Adults with Bilateral Severe to Profound Deafness.

Effects of tinnitus on cochlear implant programming (2019)
Journal Article
Pierzycki, R. H., Corner, C., Fielden, C. A., & Kitterick, P. T. (2019). Effects of tinnitus on cochlear implant programming. Trends in Hearing, 23, https://doi.org/10.1177/2331216519836624

Clinical observations suggest that tinnitus may interfere with programming cochlear implants (CIs), the process of optimizing the transmission of acoustic information to support speech perception with a CI. Despite tinnitus being highly prevalent amo... Read More about Effects of tinnitus on cochlear implant programming.

Betahistine for tinnitus (Review) (2018)
Journal Article
Wegner, I., Hall, D. A., Smit, A. L., McFerran, D., & Stegeman, I. (2018). Betahistine for tinnitus (Review). Cochrane Database of Systematic Reviews, 2018(12), Article CD013093. https://doi.org/10.1002/14651858.CD013093.pub2

Background: Tinnitus is a symptom defined as the perception of sound in the absence of an external source. In England alone there are an estimated ¾ million general practice consultations every year where the primary complaint is tinnitus, equating t... Read More about Betahistine for tinnitus (Review).

Automated quality control for within and between studies diffusion MRI data using a non-parametric framework for movement and distortion correction (2018)
Journal Article
Bastiani, M., Cottaar, M., Fitzgibbon, S. P., Suri, S., Alfaro-Almagro, F., Sotiropoulos, S. N., Jbabdi, S., & Andersson, J. (2019). Automated quality control for within and between studies diffusion MRI data using a non-parametric framework for movement and distortion correction. NeuroImage, 184, 801-812. https://doi.org/10.1016/j.neuroimage.2018.09.073

Diffusion MRI data can be affected by hardware and subject-related artefacts that can adversely affect downstream analyses. Therefore, automated quality control (QC) is of great importance, especially in large population studies where visual QC is no... Read More about Automated quality control for within and between studies diffusion MRI data using a non-parametric framework for movement and distortion correction.

Cortical correlates of speech intelligibility measured using functional near-infrared spectroscopy (fNIRS) (2018)
Journal Article
Lawrence, R. J., Wiggins, I. M., Anderson, C. A., Davies-Thompson, J., & Hartley, D. E. (2018). Cortical correlates of speech intelligibility measured using functional near-infrared spectroscopy (fNIRS). Hearing Research, 370, 53-64. https://doi.org/10.1016/j.heares.2018.09.005

Functional neuroimaging has identified that the temporal, frontal and parietal cortex support core aspects of speech processing. An objective measure of speech intelligibility based on cortical activation in these brain regions would be extremely use... Read More about Cortical correlates of speech intelligibility measured using functional near-infrared spectroscopy (fNIRS).

Altered nucleus basalis connectivity predicts treatment response in mild cognitive impairment (2018)
Journal Article
Meng, D., Li, X., Bauer, M., Taylor, J.-P., Auer, D. P., & Alzheimer's Disease Neuroimaging Initiative. (2018). Altered nucleus basalis connectivity predicts treatment response in mild cognitive impairment. Radiology, 289(3), 775-785. https://doi.org/10.1148/radiol.2018180092

Purpose: To determine whether functional connectivity (FC) mapping of nucleus basalis of Meynert (NBM) cholinergic network (hereafter, NBM FC) could provide a biomarker of central cholinergic deficits with predictive potential for response to choline... Read More about Altered nucleus basalis connectivity predicts treatment response in mild cognitive impairment.

The Developing Human Connectome Project: a minimal processing pipeline for neonatal cortical surface reconstruction (2018)
Journal Article
Makropoulos, A., Robinson, E. C., Schuh, A., Wright, R., Fitzgibbon, S., Bozek, J., Counsell, S. J., Steinweg, J., Passerat-Palmbach, J., Lenz, G., Mortari, F., Tenev, T., Duff, E. P., Bastiani, M., Cordero-Grande, L., Hughes, E., Tusor, N., Tournier, J.-D., Hutter, J., Price, A. N., …Rueckert, D. (2018). The Developing Human Connectome Project: a minimal processing pipeline for neonatal cortical surface reconstruction. NeuroImage, 173, 88-112. https://doi.org/10.1101/125526

The Developing Human Connectome Project (dHCP) seeks to create the first 4-dimensional connectome of early life. Understanding this connectome in detail may provide insights into normal as well as abnormal patterns of brain development. Following est... Read More about The Developing Human Connectome Project: a minimal processing pipeline for neonatal cortical surface reconstruction.

Patterns of grey matter loss associated with motor subscores in early Parkinson's disease (2017)
Journal Article
Li, X., Xing, Y., Martin-Bastida, A., Piccini, P., & Auer, D. P. (in press). Patterns of grey matter loss associated with motor subscores in early Parkinson's disease. NeuroImage: Clinical, 17, https://doi.org/10.1016/j.nicl.2017.11.009

Classical motor symptoms of Parkinson's disease (PD) such as tremor, rigidity, bradykinesia, and axial symptoms are graded in the Movement Disorders Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) III. It is yet to be ascertained whether... Read More about Patterns of grey matter loss associated with motor subscores in early Parkinson's disease.