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A low-cost paper-based model for on-chip human respiratory system studies (2016)
Conference Proceeding
Rahimi, R., Ochoa, M., Htwe, S. S., Donaldson, A., Zieger, M., Dokmeci, M. R., …Ziaie, B. (2016). A low-cost paper-based model for on-chip human respiratory system studies. In Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2016 (206-209). https://doi.org/10.31438/trf.hh2016.56

© 2016 TRF We present the use of hydrophobic paper as an effective semipermeable membrane, ideal for air-liquid interface cell culture applications. The surface properties of the paper is modified through selective CO2 laser-assisted scrubbing to cre... Read More about A low-cost paper-based model for on-chip human respiratory system studies.

Engineering Immunomodulatory Biomaterials To Tune the Inflammatory Response (2016)
Journal Article
Vishwakarma, A., Bhise, N. S., Evangelista, M. B., Rouwkema, J., Dokmeci, M. R., Ghaemmaghami, A. M., …Khademhosseini, A. (2016). Engineering Immunomodulatory Biomaterials To Tune the Inflammatory Response. Trends in Biotechnology, 34(6), 470-482. https://doi.org/10.1016/j.tibtech.2016.03.009

Current state-of-the-art biomedical implants and tissue engineering methods promise technologies to improve or even restore the function of diseased organs. However, one of the biggest challenges to clinical success is the lack of functional integrat... Read More about Engineering Immunomodulatory Biomaterials To Tune the Inflammatory Response.

Delivery strategies to control inflammatory response: Modulating M1–M2 polarization in tissue engineering applications (2016)
Journal Article
Alvarez, M. M., Liu, J. C., Trujillo-de Santiago, G., Cha, B. H., Vishwakarma, A., Ghaemmaghami, A. M., & Khademhosseini, A. (2016). Delivery strategies to control inflammatory response: Modulating M1–M2 polarization in tissue engineering applications. Journal of Controlled Release, 240, 349-363. https://doi.org/10.1016/j.jconrel.2016.01.026

Macrophages are key players in many physiological scenarios including tissue homeostasis. In response to injury, typically the balance between macrophage sub-populations shifts from an M1 phenotype (pro-inflammatory) to an M2 phenotype (anti-inflamma... Read More about Delivery strategies to control inflammatory response: Modulating M1–M2 polarization in tissue engineering applications.

Controlling Incoming Macrophages to Implants: Responsiveness of Macrophages to Gelatin Micropatterns under M1/M2 Phenotype Defining Biochemical Stimulations (2017)
Journal Article
Dollinger, C., Ndreu-Halili, A., Uka, A., Singh, S., Sadam, H., Neuman, T., …Vrana, N. E. (2017). Controlling Incoming Macrophages to Implants: Responsiveness of Macrophages to Gelatin Micropatterns under M1/M2 Phenotype Defining Biochemical Stimulations. Advanced Biosystems, 1(6), Article 1700041. https://doi.org/10.1002/adbi.201700041

Adverse immune reactions to implanted devices can seriously hamper the efficacy of implants. Monocyte derived macrophages play a crucial role in both initiation and resolution of the inflammatory response toward foreign bodies. As the surface microt... Read More about Controlling Incoming Macrophages to Implants: Responsiveness of Macrophages to Gelatin Micropatterns under M1/M2 Phenotype Defining Biochemical Stimulations.

High-throughput approaches for screening and analysis of cell behaviors (2017)
Journal Article
Seo, J., Shin, J. Y., Leijten, J., Jeon, O., Camci-Unal, G., Dikina, A. D., …Khademhosseini, A. (2018). High-throughput approaches for screening and analysis of cell behaviors. Biomaterials, 153, 85-101. https://doi.org/10.1016/j.biomaterials.2017.06.022

The rapid development of new biomaterials and techniques to modify them challenge our capability to characterize them using conventional methods. In response, numerous high-throughput (HT) strategies are being developed to analyze biomaterials and th... Read More about High-throughput approaches for screening and analysis of cell behaviors.