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Biased μ-opioid analgesics derived from a novel tetrapeptide class found in an Australian fungus (2019)
Journal Article
Dekan, Z., Sianati, S., Yousuf, A., Sutcliffe, K. J., Gillis, A., Mallet, C., …Christie, M. J. (in press). Biased μ-opioid analgesics derived from a novel tetrapeptide class found in an Australian fungus. Proceedings of the National Academy of Sciences,

An Australian estuarine isolate of Penicillium sp. MST-MF667 yielded three novel tetrapeptides named the bilaids with an unusual alternating LDLD chirality. Given their resemblance to known short peptide opioid agonists we elucidated that they were w... Read More