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A data-driven approach to optimising the encoding for multi-shell diffusion MRI with application to neonatal imaging (2020)
Journal Article
Tournier, J., Christiaens, D., Hutter, J., Price, A. N., Cordero-Grande, L., Hughes, E., …Hajnal, J. V. (2020). A data-driven approach to optimising the encoding for multi-shell diffusion MRI with application to neonatal imaging. NMR in Biomedicine, https://doi.org/10.1101/661348

Diffusion MRI has the potential to provide important information about the connectivity and microstructure of the human brain during normal and abnormal development, non-invasively and in vivo. Recent developments in MRI hardware and reconstruction m... Read More about A data-driven approach to optimising the encoding for multi-shell diffusion MRI with application to neonatal imaging.

XTRACT - Standardised protocols for automated tractography in the human and macaque brain (2020)
Journal Article
Warrington, S., Bryant, K., Khrapitchev, A., Sallet, J., Charquero-Ballester, M., Douaud, G., …Sotiropoulos, S. (2020). XTRACT - Standardised protocols for automated tractography in the human and macaque brain. NeuroImage, 217, https://doi.org/10.1016/j.neuroimage.2020.116923

We present a new software package with a library of standardised tractography protocols devised for the robust automated extraction of white matter tracts both in the human and the macaque brain. Using in vivo data from the Human Connectome Project (... Read More about XTRACT - Standardised protocols for automated tractography in the human and macaque brain.

Operando visualisation of battery chemistry in a sodium-ion battery by 23Na magnetic resonance imaging (2020)
Journal Article
Kendrick, E., Bray, J. M., Doswell, C. L., Pavlovskaya, G. E., Chen, L., Kishore, B., …Britton, M. M. (2020). Operando visualisation of battery chemistry in a sodium-ion battery by 23Na magnetic resonance imaging. Nature Communications, 11(1), https://doi.org/10.1038/s41467-020-15938-x

© 2020, The Author(s). Sodium-ion batteries are a promising battery technology for their cost and sustainability. This has led to increasing interest in the development of new sodium-ion batteries and new analytical methods to non-invasively, directl... Read More about Operando visualisation of battery chemistry in a sodium-ion battery by 23Na magnetic resonance imaging.

Improved fibre dispersion estimation using b-tensor encoding (2020)
Journal Article
Cottaar, M., Szczepankiewicz, F., Bastiani, M., Hernandez-Fernandez, M., Sotiropoulos, S. N., Nilsson, M., & Jbabdi, S. (2020). Improved fibre dispersion estimation using b-tensor encoding. NeuroImage, 215, https://doi.org/10.1016/j.neuroimage.2020.116832

© 2020 The Authors Measuring fibre dispersion in white matter with diffusion magnetic resonance imaging (MRI) is limited by an inherent degeneracy between fibre dispersion and microscopic diffusion anisotropy (i.e., the diffusion anisotropy expected... Read More about Improved fibre dispersion estimation using b-tensor encoding.

Towards HCP-Style Macaque Connectomes: 24-Channel 3T Multi-Array Coil, MRI Sequences and Preprocessing (2020)
Journal Article
Autio, J. A., Glasser, M. F., Ose, T., Donahue, C. J., Bastiani, M., Ohno, M., …Hayashi, T. (2020). Towards HCP-Style Macaque Connectomes: 24-Channel 3T Multi-Array Coil, MRI Sequences and Preprocessing. NeuroImage, 215, https://doi.org/10.1016/j.neuroimage.2020.116800

© 2020 The Author(s) Macaque monkeys are an important animal model where invasive investigations can lead to a better understanding of the cortical organization of primates including humans. However, the tools and methods for noninvasive image acquis... Read More about Towards HCP-Style Macaque Connectomes: 24-Channel 3T Multi-Array Coil, MRI Sequences and Preprocessing.

Cortical Complexity in Anorexia Nervosa: A Fractal Dimension Analysis (2020)
Journal Article
Collantoni, E., Madan, C. R., Meneguzzo, P., Chiappini, I., Tenconi, E., Manara, R., & Favaro, A. (2020). Cortical Complexity in Anorexia Nervosa: A Fractal Dimension Analysis. Journal of Clinical Medicine, 9(3), 833. https://doi.org/10.3390/jcm9030833

Fractal Dimension (FD) has shown to be a promising means to describe the morphology of cortical structures across different neurologic and psychiatric conditions, displaying a good sensitivity in capturing atrophy processes. In this study, we aimed a... Read More about Cortical Complexity in Anorexia Nervosa: A Fractal Dimension Analysis.

A Population-based PBPK Model for the Prediction of Time-Variant Bile Salt Disposition within GI Luminal Fluids (2020)
Journal Article
Stamatopoulos, K., Pathak, S., Marciani, L., & Turner, D. (2020). A Population-based PBPK Model for the Prediction of Time-Variant Bile Salt Disposition within GI Luminal Fluids. Molecular Pharmaceutics, 17(4), 1310-1323. https://doi.org/10.1021/acs.molpharmaceut.0c00019

In vivo studies have shown cyclic bile salt (BS) outputs during fasting whereas higher amounts have been observed in fed states. This leads to fluctuations of intestinal BS concentrations ([BS]) that can affect the rate and extent of absorption of li... Read More about A Population-based PBPK Model for the Prediction of Time-Variant Bile Salt Disposition within GI Luminal Fluids.

A simple and efficient method for polymer coating of iron oxide nanoparticles (2019)
Journal Article
Abushrida, A., Elhuni, I., Taresco, V., Marciani, L., Stolnik, S., & Garnett, M. C. (2020). A simple and efficient method for polymer coating of iron oxide nanoparticles. Journal of Drug Delivery Science and Technology, 55, https://doi.org/10.1016/j.jddst.2019.101460

Iron oxide nanoparticles (IONP) have many possible uses including as MRI contrast agents, for drug delivery and cell labelling, but need to be stabilised and to be rendered biocompatible through appropriate coatings. Many current coatings are subopti... Read More about A simple and efficient method for polymer coating of iron oxide nanoparticles.

Imaging Measurement of Whole Gut Transit Time in Paediatric and Adult Functional Gastrointestinal Disorders: A Systematic Review and Narrative Synthesis (2019)
Journal Article
Sharif, H., Devadason, D., Abrehart, N., Stevenson, R., & Marciani, L. (2019). Imaging Measurement of Whole Gut Transit Time in Paediatric and Adult Functional Gastrointestinal Disorders: A Systematic Review and Narrative Synthesis. Diagnostics, 9(4), https://doi.org/10.3390/diagnostics9040221

Background: functional gastrointestinal disorders (FGID) are common conditions in children and adults, often associated with abnormalities of whole gut transit. Currently, transit tests can be performed using several imaging methods including trackin... Read More about Imaging Measurement of Whole Gut Transit Time in Paediatric and Adult Functional Gastrointestinal Disorders: A Systematic Review and Narrative Synthesis.

Mechanisms and Risk Factors Contributing to Visual Field Deficits following Stereotactic Laser Amygdalohippocampotomy (2019)
Journal Article
Voets, N. L., Alvarez, I., Qiu, D., Leatherday, C., Willie, J. T., Sotiropoulos, S., …Drane, D. L. (2019). Mechanisms and Risk Factors Contributing to Visual Field Deficits following Stereotactic Laser Amygdalohippocampotomy. Stereotactic and Functional Neurosurgery, 97(4), 255–265. https://doi.org/10.1159/000502701

Selective laser amygdalohippocampotomy (SLAH) is a minimally invasive surgical treatment for medial temporal lobe epilepsy. Visual field deficits (VFDs) are a significant potential complication. The objective of this study was to determine the relati... Read More about Mechanisms and Risk Factors Contributing to Visual Field Deficits following Stereotactic Laser Amygdalohippocampotomy.

Glycemic, Gastrointestinal, Hormonal and Appetitive Responses to Pearl Millet or Oats Porridge Breakfasts: a Randomized, Crossover Trial in Healthy Humans (2019)
Journal Article
Alyami, J., Whitehouse, E., Yakubov, G. E., Pritchard, S. E., Hoad, C. L., Blackshaw, E., …Marciani, L. (2019). Glycemic, Gastrointestinal, Hormonal and Appetitive Responses to Pearl Millet or Oats Porridge Breakfasts: a Randomized, Crossover Trial in Healthy Humans. British Journal of Nutrition, https://doi.org/10.1017/S0007114519001880

Whole grain cereal breakfast consumption has been associated with beneficial effects on glucose and insulin metabolism as well as satiety. Pearl millet is a popular ancient grain variety that can be grown in hot, dry regions. However, little is known... Read More about Glycemic, Gastrointestinal, Hormonal and Appetitive Responses to Pearl Millet or Oats Porridge Breakfasts: a Randomized, Crossover Trial in Healthy Humans.

Increased fasting small bowel water content in untreated coeliac disease and scleroderma as assessed by MRI (2019)
Journal Article
Lam, C., Sanders, D., Lanyon, P., Garsed, K., Foley, S., & Pritchard, S. (2019). Increased fasting small bowel water content in untreated coeliac disease and scleroderma as assessed by MRI. United European Gastroenterology Journal, 7(10), 1353-1360 . https://doi.org/10.1177/2050640619860372

Background and aims: The regular overnight migrating motor complex (MMC) ensures that the normal fasting small bowel water content (SBWC) is minimised. We have applied our recently validated non-invasive magnetic resonance technique to assess SBWC in... Read More about Increased fasting small bowel water content in untreated coeliac disease and scleroderma as assessed by MRI.

Joint modelling of diffusion MRI and microscopy (2019)
Journal Article
Howard, A. F., Mollink, J., Kleinnijenhuis, M., Pallebage-Gamarallage, M., Bastiani, M., Cottaar, M., …Jbabdi, S. (2019). Joint modelling of diffusion MRI and microscopy. NeuroImage, 201, https://doi.org/10.1016/j.neuroimage.2019.116014

The combination of diffusion MRI (dMRI) with microscopy provides unique opportunities to study microstructural features of tissue, particularly when acquired in the same sample. Microscopy is frequently used to validate dMRI microstructure models, ad... Read More about Joint modelling of diffusion MRI and microscopy.

Short-range ordering in a battery electrode, the ‘cation-disordered’ rocksalt Li1.25Nb0.25Mn0.5O2 (2019)
Journal Article
Jones, M. A., Reeves, P. J., Seymour, I. D., Cliffe, M. J., Dutton, S. E., & Grey, C. P. (2019). Short-range ordering in a battery electrode, the ‘cation-disordered’ rocksalt Li1.25Nb0.25Mn0.5O2. Chemical Communications, 55(61), 9027-9030. doi:10.1039/c9cc04250d

Cation order, with a local structure related to γ-LiFeO2, is observed in the nominally cation-disordered Li-excess rocksalt Li1.25Nb0.25Mn0.5O2via X-ray diffraction, neutron pair distribution function analysis, magnetic susceptibility and NMR spectro... Read More about Short-range ordering in a battery electrode, the ‘cation-disordered’ rocksalt Li1.25Nb0.25Mn0.5O2.

Increased fasting small-bowel water content in untreated coeliac disease and scleroderma as assessed by magnetic resonance imaging (2019)
Journal Article
Lam, C., Sanders, D., Lanyon, P., Garsed, K., Foley, S., Pritchard, S., …Spiller, R. (2019). Increased fasting small-bowel water content in untreated coeliac disease and scleroderma as assessed by magnetic resonance imaging. United European Gastroenterology Journal, 7(10), 1353-1360 . https://doi.org/10.1177/2050640619860372

Background and aims: The regular overnight migrating motor complex (MMC) ensures that the normal fasting small bowel water content (SBWC) is minimised. We have applied our recently validated non-invasive magnetic resonance technique to assess SBWC... Read More about Increased fasting small-bowel water content in untreated coeliac disease and scleroderma as assessed by magnetic resonance imaging.

Prediction of Stroke Risk by Detection of Hemorrhage in Carotid Plaques: Meta-Analysis of Individual Patient Data (2019)
Journal Article
Schindler, A., Schinner, R., Altaf, N., Hosseini, A. A., Simpson, R. J., Esposito-Bauer, L., …Saam, T. (2019). Prediction of Stroke Risk by Detection of Hemorrhage in Carotid Plaques: Meta-Analysis of Individual Patient Data. JACC: Cardiovascular Imaging, https://doi.org/10.1016/j.jcmg.2019.03.028

Objectives The goal of this study was to compare the risk of stroke between patients with carotid artery disease with and without the presence of intraplaque hemorrhage (IPH) on magnetic resonance imaging. Background IPH in carotid stenosis incr... Read More about Prediction of Stroke Risk by Detection of Hemorrhage in Carotid Plaques: Meta-Analysis of Individual Patient Data.

Data visualization for inference in tomographic brain imaging (2019)
Journal Article
Pernet, C., & Madan, C. R. (2019). Data visualization for inference in tomographic brain imaging. European Journal of Neuroscience,

Tomographic brain imaging has a rich iconography. Whilst figures are prepared for scientific communication (i.e., directed to other researchers) they also often end-up on magazine and journal covers (i.e., directed to a lay audience). Scientific figu... Read More about Data visualization for inference in tomographic brain imaging.

MRI of the colon in the pharmaceutical field: the future before us (2019)
Journal Article
Sulaiman, S., & Marciani, L. (2019). MRI of the colon in the pharmaceutical field: the future before us. Pharmaceutics, 11(4), https://doi.org/10.3390/pharmaceutics11040146

Oral solid drug formulation is the most common route for administration and it is vital to increase knowledge of the gastrointestinal physiological environment to understand dissolution and absorption processes and to develop reliable biorelevant in... Read More about MRI of the colon in the pharmaceutical field: the future before us.

MRS and DTI evidence of progressive posterior cingulate cortex and corpus callosum injury in the hyper-acute phase after Traumatic Brain Injury (2019)
Journal Article
Lawrence, T. P., Steel, A., Ezra, M., Speirs, M., Pretorius, P. M., Douaud, G., …Voets, N. L. (2019). MRS and DTI evidence of progressive posterior cingulate cortex and corpus callosum injury in the hyper-acute phase after Traumatic Brain Injury. Brain Injury, https://doi.org/10.1080/02699052.2019.1584332

The posterior cingulate cortex (PCC) and corpus callosum (CC) are susceptible to trauma, but injury often evades detection. PCC Metabolic disruption may predict CC white matter tract injury and the secondary cascade responsible for progression. While... Read More about MRS and DTI evidence of progressive posterior cingulate cortex and corpus callosum injury in the hyper-acute phase after Traumatic Brain Injury.



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