In vitro determination of the protein quality of maize varieties cultivated in Malawi using the INFOGEST digestion method (2023)
Journal Article
Muleya, M., Li, D., Chiutsi-Phiri, G., Botoman, L., Brameld, J. M., & Salter, A. M. (2023). In vitro determination of the protein quality of maize varieties cultivated in Malawi using the INFOGEST digestion method. Heliyon, 9(9), Article e19797. https://doi.org/10.1016/j.heliyon.2023.e19797

There is an urgent need to alleviate protein deficiencies in low-income countries where cereal-based diets dominate. The objective of this study was to use the INFOGEST static digestion method and a recently established analytical workflow to determi... Read More about In vitro determination of the protein quality of maize varieties cultivated in Malawi using the INFOGEST digestion method.

Fermentation technology enhances the nutritional quality of underutilized Bambara groundnut – a review (2023)
Journal Article
Tee, A. J., Lim, Y. S., Brameld, J. M., Massawe, F., Parr, T., & Salter, A. M. (2023). Fermentation technology enhances the nutritional quality of underutilized Bambara groundnut – a review. Food Biotechnology, 37(2), 106-135. https://doi.org/10.1080/08905436.2023.2201307

Bambara groundnut (BG) offers great potential for sustainable food and nutritional security in the face of a growing population and changing climate. However, its utilization remains restricted by the hard-to-cook phenomenon of seed and the presence... Read More about Fermentation technology enhances the nutritional quality of underutilized Bambara groundnut – a review.

A Comparison of Primary Human Hepatocytes and Hepatoma Cell Lines to Model the Effects of Fatty Acids, Fructose and Glucose on Liver Cell Lipid Accumulation (2022)
Journal Article
Huggett, Z. J., Smith, A., De Vivo, N., Gomez, D., Jethwa, P., Brameld, J. M., …Salter, A. M. (2022). A Comparison of Primary Human Hepatocytes and Hepatoma Cell Lines to Model the Effects of Fatty Acids, Fructose and Glucose on Liver Cell Lipid Accumulation. Nutrients, 15(1), Article 40. https://doi.org/10.3390/nu15010040

Non-alcoholic fatty liver disease (NAFLD) begins with lipid accumulation within hepatocytes, but the relative contributions of different macronutrients is still unclear. We investigated the impact of fatty acids, glucose and fructose on lipid accumul... Read More about A Comparison of Primary Human Hepatocytes and Hepatoma Cell Lines to Model the Effects of Fatty Acids, Fructose and Glucose on Liver Cell Lipid Accumulation.

The effects of exogenous fibrolytic enzymes on the in vitro release of xylooligosaccharides and monosaccharides varies across six varieties of wheat (2022)
Journal Article
Dale, T., Bedford, M. R., King, J., Tucker, G. A., Brameld, J. M., & Parr, T. (2023). The effects of exogenous fibrolytic enzymes on the in vitro release of xylooligosaccharides and monosaccharides varies across six varieties of wheat. Animal Feed Science and Technology, 295, Article 115526. https://doi.org/10.1016/j.anifeedsci.2022.115526

Wheat is a widely used cereal grain for pig and poultry feeds globally. Despite this, there are noticeable differences in its nutritive value, potentially due to varying characteristics like inherent non-starch polysaccharide (NSP) content and compos... Read More about The effects of exogenous fibrolytic enzymes on the in vitro release of xylooligosaccharides and monosaccharides varies across six varieties of wheat.

The Winged Bean Genome: Winged Bean—One Species Supermarket (2022)
Book Chapter
Tsoutsoura, N., Chong, Y. T., Ho, W. K., Chai, H. H., Tanzi, A. S., Salazar-Licea, L., …Mayes, S. (2022). The Winged Bean Genome: Winged Bean—One Species Supermarket. In M. A. Chapman (Ed.), Underutilised Crop Genomes (315-336). Springer International Publishing. https://doi.org/10.1007/978-3-031-00848-1_17

Climate change, population growth and increasingly homogenised diets are a threat to food security and human nutritional status. There is an urgent need to incorporate highly nutritious crops into the human diet to provide new sources of nutrition, t... Read More about The Winged Bean Genome: Winged Bean—One Species Supermarket.

The effects of exogenous fibrolytic enzymes on the in vitro generation of xylooligosaccharides and monosaccharides is dependent upon cereal type (2022)
Journal Article
Dale, T., Bedford, M. R., Tucker, G. A., Brameld, J. M., & Parr, T. (2022). The effects of exogenous fibrolytic enzymes on the in vitro generation of xylooligosaccharides and monosaccharides is dependent upon cereal type. Animal Feed Science and Technology, 292, Article 115406. https://doi.org/10.1016/j.anifeedsci.2022.115406

Fibrolytic enzymes are routinely added to non-ruminant livestock feeds to help degrade the non-starch polysaccharide (NSP) contents and thereby improve feed efficiency. This study investigated the range of xylooligosaccharides (XOS) and monosaccharid... Read More about The effects of exogenous fibrolytic enzymes on the in vitro generation of xylooligosaccharides and monosaccharides is dependent upon cereal type.

Effect of AAV-mediated overexpression of ATF5 and downstream targets of an integrated stress response in murine skeletal muscle (2021)
Journal Article
Brearley-Sholto, M. C., Loczenski-Brown, D. M., Jones, S., Daniel, Z. C., Ebling, F. J., Parr, T., & Brameld, J. M. (2021). Effect of AAV-mediated overexpression of ATF5 and downstream targets of an integrated stress response in murine skeletal muscle. Scientific Reports, 11(1), 1-13. https://doi.org/10.1038/s41598-021-99432-4

We previously reported that growth promoter-induced skeletal muscle hypertrophy co-ordinately upregulated expression of genes associated with an integrated stress response (ISR), as well as potential ISR regulators. We therefore used Adeno-Associated... Read More about Effect of AAV-mediated overexpression of ATF5 and downstream targets of an integrated stress response in murine skeletal muscle.

In vitro Effects of Biologically Active Vitamin D on Myogenesis: A Systematic Review (2021)
Journal Article
Alliband, K. H., Kozhevnikova, S. V., Parr, T., Jethwa, P. H., & Brameld, J. M. (2021). In vitro Effects of Biologically Active Vitamin D on Myogenesis: A Systematic Review. Frontiers in Physiology, 12, Article 736708. https://doi.org/10.3389/fphys.2021.736708

Vitamin D (VD) deficiency is associated with muscle weakness. A reduction in the incidence of falls in the elderly following VD supplementation and identification of the VD receptor within muscle cells suggests a direct effect of VD on muscle, but li... Read More about In vitro Effects of Biologically Active Vitamin D on Myogenesis: A Systematic Review.

Suitability of insects for animal feeding. (2021)
Book Chapter
Hawkey, K., Brameld, J., Parr, T., Salter, A., & Hall, H. (2021). Suitability of insects for animal feeding. In H. Hall, E. Fitches, & R. Smith (Eds.), Insects as Animal Feed: Novel Ingredients for Use in Pet, Aquaculture and Livestock Diets (26-38). CAB International. https://doi.org/10.1079/9781789245929.0004

This chapter explores the nutritional composition of insects and the potential benefits and drawbacks for their inclusion into pet, poultry, pig, ruminant and aquatic animal feeds. Six species are most commonly described for use in animal feed, namel... Read More about Suitability of insects for animal feeding..

98 The effect of mezquite pod flour in a wheat-based diet on broiler chicken growth performance (2021)
Journal Article
Bone, G., Parr, T., Brameld, J., Elmes, M., Gonzalez-Carranza, Z., & Koech, O. (2021). 98 The effect of mezquite pod flour in a wheat-based diet on broiler chicken growth performance. Animal - Science proceedings, 12(1), 77. https://doi.org/10.1016/j.anscip.2021.03.099

Application Inclusion of Mezquite pod flour in broiler chicken diets significantly reduced weight gain, this could inform a recommendation against the use of non-processed Mezquite in broiler chicken diets. Introduction Mezquite is an under-utilised... Read More about 98 The effect of mezquite pod flour in a wheat-based diet on broiler chicken growth performance.