All Outputs (16)

Sensing the Spin State of Room-Temperature Switchable Cyanometallate Frameworks with Nitrogen-Vacancy Centers in Nanodiamonds (2024)
Journal Article

Room-temperature magnetically switchable materials play a vital role in current and upcoming quantum technologies, such as spintronics, molecular switches, and data storage devices. The increasing miniaturization of device architectures produces a ne... Read More about Sensing the Spin State of Room-Temperature Switchable Cyanometallate Frameworks with Nitrogen-Vacancy Centers in Nanodiamonds.

Nitrogen vacancy defects in single-particle nanodiamonds sense paramagnetic transition metal spin noise from nanoparticles on a transmission electron microscopy grid (2023)
Journal Article

Spin-active nanomaterials play a vital role in current and upcoming quantum technologies, such as spintronics, data storage and computing. To advance the design and application of these materials, methods to link size, shape, structure, and chemical... Read More about Nitrogen vacancy defects in single-particle nanodiamonds sense paramagnetic transition metal spin noise from nanoparticles on a transmission electron microscopy grid.

Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer (2023)
Journal Article

N6-methyladenosine (m6A) is the most abundant internal mRNA modification and is dynamically regulated through distinct protein complexes that methylate, demethylate, and/or interpret the m6A modification. These proteins, and the m6A modification, are... Read More about Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer.

Widefield, Spatiotemporal Mapping of Spontaneous Activity of Mouse Cultured Neuronal Networks Using Quantum Diamond Sensors (2020)
Journal Article

Quantum diamond sensors containing Nitrogen Vacancy (NV) centers were integrated into the culture of spontaneously electrically active cultures of live mouse primary cortical neurons. Two diamond formats were used enabling extracellular studies of ce... Read More about Widefield, Spatiotemporal Mapping of Spontaneous Activity of Mouse Cultured Neuronal Networks Using Quantum Diamond Sensors.

Dynamic Quantum Sensing of Paramagnetic Species Using Nitrogen-Vacancy Centers in Diamond (2019)
Journal Article

Quantum Sensing in a Physiological-Like Cell Niche Using Fluorescent Nanodiamonds Embedded in Electrospun Polymer Nanofibers (2019)
Journal Article

© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Fluorescent nanodiamonds (fNDs) containing nitrogen vacancy (NV) centers are promising candidates for quantum sensing in biological environments. This work describes the fabrication and implementati... Read More about Quantum Sensing in a Physiological-Like Cell Niche Using Fluorescent Nanodiamonds Embedded in Electrospun Polymer Nanofibers.

Progress in low-field benchtop NMR spectroscopy in chemical and biochemical analysis (2019)
Journal Article

© 2019 Elsevier B.V. The employment of spectroscopically-resolved NMR techniques as analytical probes have previously been both prohibitively expensive and logistically challenging in view of the large sizes of high-field facilities. However, with re... Read More about Progress in low-field benchtop NMR spectroscopy in chemical and biochemical analysis.

Low-field, benchtop NMR spectroscopy as a potential tool for point-of-care diagnostics of metabolic conditions: Validation, protocols and computational models (2018)
Journal Article

Novel sensing technologies for liquid biopsies offer promising prospects for the early detection of metabolic conditions through omics techniques. Indeed, high-field nuclear magnetic resonance (NMR) facilities are routinely used for metabolomics inve... Read More about Low-field, benchtop NMR spectroscopy as a potential tool for point-of-care diagnostics of metabolic conditions: Validation, protocols and computational models.

Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media (2018)
Journal Article

In vivo imaging of self-illuminating bio-and chemiluminescent reporters is used to observe the physiology of small animals. However, strong light scattering by biological tissues results in poor spatial resolution of the optical imaging, which also d... Read More about Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media.

Label-free, high resolution, multi-modal light microscopy for discrimination of live stem cell differentiation status (2018)
Journal Article

A label-free microscopy method for assessing the differentiation status of stem cells is presented with potential application for characterization of therapeutic stem cell populations. The microscopy system is capable of characterizing live cells bas... Read More about Label-free, high resolution, multi-modal light microscopy for discrimination of live stem cell differentiation status.

Nanoscale ultrasound-switchable FRET based liposomes for near-infrared fluorescence imaging in optically turbid media (2017)
Journal Article

A new approach to fluorescence imaging in optically turbid media centered on the use of nanoscale ultrasound-switchable FRET based liposome contrast agents is reported. Liposomes containing lipophilic carbocyanine dyes as FRET pairs with emission wav... Read More about Nanoscale ultrasound-switchable FRET based liposomes for near-infrared fluorescence imaging in optically turbid media.

6. Label-free selective plane illumination microscopy of tissue samples (2017)
Journal Article

Ultrasound induced fluorescence of nanoscale liposome contrast agents (2016)
Journal Article

A new imaging contrast agent is reported that provides an increased fluorescent signal upon application of ultrasound (US). Liposomes containing lipids labelled with pyrene were optically excited and the excimer fluorescence emission intensity was de... Read More about Ultrasound induced fluorescence of nanoscale liposome contrast agents.

Numerical investigation of the mechanisms of ultrasound-modulated bioluminescence tomography (2015)
Journal Article

Objective: A hybrid imaging technique, Ultrasound Modulated Luminescence Tomography, that uses ultrasound to modulate diffusely propagating light has been shown to improve the spatial resolution of optical images. This paper is to investigate the und... Read More about Numerical investigation of the mechanisms of ultrasound-modulated bioluminescence tomography.

Pulsed ultrasound modulated optical tomography with harmonic lock-in holography detection (2013)
Journal Article

A method that uses digital heterodyne holography reconstruction to extract scattered light modulated by a singlecycle ultrasound (US) burst is demonstrated and analyzed. An US burst is used to shift the pulsed laser frequency by a series of discrete... Read More about Pulsed ultrasound modulated optical tomography with harmonic lock-in holography detection.

Cytoplasmic RNA in undifferentiated neural stem cells: a potential label-free Raman spectral marker for assessing the undifferentiated status (2012)
Journal Article

Raman microspectroscopy (rms) was used to identify, image, and quantify potential molecular markers for label-free monitoring the differentiation status of live neural stem cells (NSCs) in vitro. Label-free noninvasive techniques for characterization... Read More about Cytoplasmic RNA in undifferentiated neural stem cells: a potential label-free Raman spectral marker for assessing the undifferentiated status.