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Pulsed ultrasound modulated optical tomography with harmonic lock-in holography detection

Ruan, Haowen; Mather, Melissa; Morgan, Stephen P.

Authors

Haowen Ruan

Melissa Mather

Stephen P. Morgan steve.morgan@nottingham.ac.uk

Abstract

A method that uses digital heterodyne holography reconstruction to extract scattered light modulated by a singlecycle ultrasound (US) burst is demonstrated and analyzed. An US burst is used to shift the pulsed laser frequency by a series of discrete harmonic frequencies which are then locked on a CCD. The analysis demonstrates that the unmodulated light’s contribution to the detected signal can be canceled by appropriate selection of the pulse repetition frequency. It is also shown that the modulated signal can be maximized by selecting a pulse sequence which consists of a pulse followed by its inverted counterpart. The system is used to image a 12 mm thick chicken breast with 2 mm wide optically absorbing objects embedded at the midplane. Furthermore, the method can be
revised to detect the nonlinear US modulated signal by locking at the second harmonic US frequency. © 2013
Optical Society of America

Journal Article Type Article
Publication Date Jul 1, 2013
Journal Journal of the Optical Society of America A
Print ISSN 1084-7529
Electronic ISSN 1084-7529
Publisher Optical Society of America
Peer Reviewed Peer Reviewed
Volume 30
Issue 7
Institution Citation Ruan, H., Mather, M., & Morgan, S. P. (2013). Pulsed ultrasound modulated optical tomography with harmonic lock-in holography detection. Journal of the Optical Society of America A, 30(7), doi:10.1364/JOSAA.30.001409
DOI https://doi.org/10.1364/JOSAA.30.001409
Publisher URL http://www.opticsinfobase.org/josaa/abstract.cfm?uri=josaa-30-7-1409
Copyright Statement Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0




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