Design, Synthesis, and Evaluation of Lung-Retentive Prodrugs for Extending the Lung Tissue Retention of Inhaled Drugs (2022)
Journal Article
Ayre, J., Redmond, J. M., Vitulli, G., Tomlinson, L., Weaver, R., Comeo, E., Bosquillon, C., & Stocks, M. J. (2022). Design, Synthesis, and Evaluation of Lung-Retentive Prodrugs for Extending the Lung Tissue Retention of Inhaled Drugs. Journal of Medicinal Chemistry, 65(14), 9802-9818. https://doi.org/10.1021/acs.jmedchem.2c00416

A major limitation of pulmonary delivery is that drugs can exhibit suboptimal pharmacokinetic profiles resulting from rapid elimination from the pulmonary tissue. This can lead to systemic side effects and a short duration of action. A series of diba... Read More about Design, Synthesis, and Evaluation of Lung-Retentive Prodrugs for Extending the Lung Tissue Retention of Inhaled Drugs.

The Centre for Rehabilitation and Ageing Research in Nottingham and Derby 2022. Excellence in care through world class research (2022)
Preprint / Working Paper
Gladman, Logan, Gordon, Harwood, Goldberg, & Radford. The Centre for Rehabilitation and Ageing Research in Nottingham and Derby 2022. Excellence in care through world class research

It is with pleasure that we present this brochure outlining the work of the Centre for Rehabilitation and Ageing and Research (CRAR) at the University of Nottingham and its partner NHS Trusts in Nottingham, and Derby and Burton.