Research Repository

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What Makes a Rabbit Cute? Preference for Rabbit Faces Differs according to Skull Morphology and Demographic Factors (2019)
Journal Article
Harvey, N. D., Oxley, J. A., Miguel-Pacheco, G., Gosling, E. M., & Farnworth, M. (2019). What Makes a Rabbit Cute? Preference for Rabbit Faces Differs according to Skull Morphology and Demographic Factors. Animals, 9(10), https://doi.org/10.3390/ani9100728

Domesticated rabbits typically exhibit shorter, flatter skulls than their wild counterparts (brachycephalism). However, brachycephaly is associated with considerable health problems, including problems with dentition. The aim of this study was to est... Read More

First detection of Hepatitis E virus (Orthohepevirus C) in wild brown rats ( Rattus norvegicus ) from Great Britain (2019)
Journal Article
Murphy, E. G., Williams, N. J., Jennings, D., Chantrey, J., Verin, R., Grierson, S., …Bennett, M. (2019). First detection of Hepatitis E virus (Orthohepevirus C) in wild brown rats ( Rattus norvegicus ) from Great Britain. Zoonoses and Public Health, 1-9. doi:10.1111/zph.12581

In the United Kingdom, there has been an increase in the number of hepatitis E virus (HEV) infections in people annually since 2010. Most of these are thought to be indigenously acquired Orthohepevirus A genotype 3 (HEV G3), which has been linked to... Read More

Development and validation of a new standardised data collection tool to aid in the diagnosis of canine skin allergies (2019)
Journal Article
Harvey, N. D., Shaw, S. C., Blott, S. C., Vàzquez-Diosdado, J. A., & England, G. C. W. (2019). Development and validation of a new standardised data collection tool to aid in the diagnosis of canine skin allergies. Scientific Reports, 9, doi:10.1038/s41598-019-39630-3

Canine atopic dermatitis (cAD) is a common hereditary clinical syndrome in domestic dogs with no definitive diagnostic tests, which causes marked morbidity and has a high economic impact internationally. We created a novel questionnaire for Labrador... Read More

The commercial pig as a model of spontaneously-occurring osteoarthritis (2019)
Journal Article
Macfadyen, M. A., Daniel, Z., Kelly, S., Parr, T., Brameld, J. M., Murton, A. J., & Jones, S. W. (2019). The commercial pig as a model of spontaneously-occurring osteoarthritis. BMC Musculoskeletal Disorders, 20, doi:10.1186/s12891-019-2452-0

Background: Preclinical osteoarthritis models where damage occurs spontaneously may better reflect the initiation and development of human osteoarthritis. The aim was to assess the commercial pig as a model of spontaneous osteoarthritis development b... Read More

Do Antiretroviral Drugs Protect From Multiple Sclerosis By Inhibiting Expression Of MS-Associated Retrovirus? (2019)
Journal Article
Morandi, E., Tanasescu, R., Tarlington, R., Constantin-Teodosiu, D., & Gran, B. (2019). Do Antiretroviral Drugs Protect From Multiple Sclerosis By Inhibiting Expression Of MS-Associated Retrovirus?. Frontiers in Immunology, 9, doi:10.3389/fimmu.2018.03092

The expression of human endogenous retroviruses (HERVs) has been associated with Multiple Sclerosis (MS). The MS-related retrovirus (MSRV/HERV-W) has the potential to activate inflammatory immunity, which could promote both susceptibility and progres... Read More

Transcriptomic insights into the early host-pathogen interaction of cat intestine with Toxoplasma gondii (2018)
Journal Article
Wang, M., Zhang, F., Elsheikha, H. M., Zhang, N., He, J., Luo, J., & Zhu, X. (2018). Transcriptomic insights into the early host-pathogen interaction of cat intestine with Toxoplasma gondii. Parasites and Vectors, 11(1), doi:10.1186/s13071-018-3179-8

Background: Although sexual reproduction of the parasite Toxoplasma gondii exclusively occurs in the cat intestine, knowledge about the alteration of gene expression in the intestine of cats infected with T. gondii is still limited. Here, we investig... Read More

The pervasive effects of recombinant Fasciola gigantica Ras-related protein Rab10 on the functions of goat peripheral blood mononuclear cells (2018)
Journal Article
Tian, A., Lu, M., Zhang, F., Calderón-Mantilla, G., Petsalaki, E., Tian, X., …Zhu, X. (2018). The pervasive effects of recombinant Fasciola gigantica Ras-related protein Rab10 on the functions of goat peripheral blood mononuclear cells. Parasites and Vectors, 11, doi:10.1186/s13071-018-3148-2

Background: Fasciola gigantica-induced immunomodulation is a major hurdle faced by the host for controlling infection. Here, we elucidated the role of F. gigantica Ras-related protein Rab10 (FgRab10) in the modulation of key functions of peripheral b... Read More

The Status of Pet Rabbit Breeding and Online Sales in the UK: A Glimpse into an Otherwise Elusive Industry (2018)
Journal Article
Gosling, E., Vázquez-Diosdado, J., & Harvey, N. (2018). The Status of Pet Rabbit Breeding and Online Sales in the UK: A Glimpse into an Otherwise Elusive Industry. Animals, 8(11), 199. doi:10.3390/ani8110199

Conditions of pet rabbit breeding colonies and breeder practices are undocumented and very little is known about the pet rabbit sales market. Here, multiple methods were employed to investigate this sector of the UK pet industry. A freedom of informa... Read More

Preliminary investigation of urine N-telopeptide concentration as a biomarker of bone resorption in dogs receiving glucocorticoids: Urinary NTx in glucocorticoid treated dogs (2017)
Journal Article
Adamany, J. L., Cross, G. F., Gardner, D., & Dunning, M. D. (2017). Preliminary investigation of urine N-telopeptide concentration as a biomarker of bone resorption in dogs receiving glucocorticoids: Urinary NTx in glucocorticoid treated dogs. Journal of Small Animal Practice, 58(7), 403-407. doi:10.1111/jsap.12675

Objectives The influence of glucocorticoid therapy on bone resorption in dogs using a urine N‐telopeptide assay was investigated. Materials and Methods Thirty‐one dogs receiving oral glucocorticoids and 31 age‐matched healthy control dogs were e... Read More

Proteomic profiling of mouse liver following acute Toxoplasma gondii infection (2016)
Journal Article
He, J., Ma, J., Elsheikha, H. M., Song, H., Zhou, D., & Zhu, X. (2016). Proteomic profiling of mouse liver following acute Toxoplasma gondii infection. PLoS ONE, 11(3), 1-15. doi:10.1371/journal.pone.0152022

Toxoplasma gondii remains a global public health problem. However, its pathophysiology is still not-completely understood particularly the impact of infection on host liver metabolism. We performed iTRAQ-based proteomic analysis to evaluate early liv... Read More

Alcelaphine herpesvirus 1 glycoprotein B: recombinant expression and antibody recognition (2015)
Journal Article
Dry, I., Todd, H., Deane, D., Percival, A., Mclean, K., Inglis, N. F., …Russell, G. C. (2016). Alcelaphine herpesvirus 1 glycoprotein B: recombinant expression and antibody recognition. Archives of Virology, 161(3), 613-619. doi:10.1007/s00705-015-2701-y

The gammaherpesvirus alcelaphine herpesvirus 1 (AlHV-1) causes fatal malignant catarrhal fever (MCF) in susceptible species including cattle, but infects its reservoir host, wildebeest, without causing disease. Pathology in cattle may be influenced b... Read More