All Outputs (111)

Discovery of os cordis in the cardiac skeleton of chimpanzees (Pan troglodytes) (2020)
Journal Article

© 2020, The Author(s). Cardiovascular diseases, especially idiopathic myocardial fibrosis, is one of the most significant causes of morbidity and mortality in captive great apes. This study compared the structure and morphology of 16 hearts from chim... Read More about Discovery of os cordis in the cardiac skeleton of chimpanzees (Pan troglodytes).

Mouse Tumor Models for Advanced Cancer Immunotherapy (2020)
Journal Article

Recent advances in the development of new methods of cancer immunotherapy require the production of complex cancer animal models that reliably reflect the complexity of the tumor and its microenvironment. Mice are good animals to create tumor models... Read More about Mouse Tumor Models for Advanced Cancer Immunotherapy.

The Function of Seven Transmembrane Receptors in the Cardiovascular System and Their Role in the Development of Cardiomyopathy (2020)
Book Chapter

The G-protein-coupled receptors (GPCRs, also called seven-transmembrane receptor, 7TMRs, or heptahelical receptor) are a conserved family of seven transmembrane receptors which are essential not only in the healthy heart and blood vessels but also in... Read More about The Function of Seven Transmembrane Receptors in the Cardiovascular System and Their Role in the Development of Cardiomyopathy.

Epidemiology and risk factors of osteosarcoma (2020)
Journal Article

Osteosarcoma is a rare tumor diagnosed at any age; however younger age is a common risk factor. In addition, multiple factors are believed to contribute to higher rates of osteosarcoma, particularly race and gender. Although diagnosed worldwide, oste... Read More about Epidemiology and risk factors of osteosarcoma.

Investigation into Whether Proximal Suspensory Desmitis of the Hindlimb Could Predispose Horses to Sacroiliac Disease (2020)
Book Chapter

Cell Culture Based in vitro Test Systems for Anticancer Drug Screening (2020)
Journal Article

The development of new high-tech systems for screening anticancer drugs is one of the main problems of preclinical screening. Poor correlation between preclinical in vitro and in vivo data with clinical trials remains a major concern. The choice of t... Read More about Cell Culture Based in vitro Test Systems for Anticancer Drug Screening.

Blood Vessels Under the Microscope (2020)
Journal Article

This paper looks at blood vessels. All humans and animals have blood vessels, including your pet rabbit or dog, a whale or a giraffe! We need blood vessels to stay alive. This paper answers many questions, including what blood vessels are used for an... Read More about Blood Vessels Under the Microscope.

Morphological and imaging evaluation of the metacarpophalangeal and metatarsophalangeal joints in healthy and lame donkeys (2019)
Journal Article

The donkey is of socio-economic value yet imaging techniques in both healthy and abnormal limbs are a limiting factor in research and medicine. The objective was to determine anatomical features of both healthy and clinically abnormal donkey metacarp... Read More about Morphological and imaging evaluation of the metacarpophalangeal and metatarsophalangeal joints in healthy and lame donkeys.

Production and Application of Multicistronic Constructs for Various Human Disease Therapies (2019)
Journal Article

The development of multicistronic vectors has opened up new opportunities to address the fundamental issues of molecular and cellular biology related to the need for the simultaneous delivery and joint expression of several genes. To date, the exampl... Read More about Production and Application of Multicistronic Constructs for Various Human Disease Therapies.

Mechanistic investigations into the encapsulation and release of small molecules and proteins from a supramolecular nucleoside gel in vitro and in vivo (2019)
Journal Article

Supramolecular gels have recently emerged as promising biomaterials for the delivery of a wide range of bioactive molecules, from small hydrophobic drugs to large biomolecules such as proteins. Although it has been demonstrated that each encapsulated... Read More about Mechanistic investigations into the encapsulation and release of small molecules and proteins from a supramolecular nucleoside gel in vitro and in vivo.

Potential therapeutic application of mesenchymal stem cells in ophthalmology (2019)
Journal Article

At present a wide variety of methods have been proposed to treat eye disorders, drug therapies are most commonly used. It should be noted that effective treatment modalities especially for degeneration of the retina and optic nerve are lacking. In th... Read More about Potential therapeutic application of mesenchymal stem cells in ophthalmology.

Physics of animal health: on the mechano-biology of hoof growth and form (2019)
Journal Article

Global inequalities in economic access and agriculture productivity imply that a large number of developing countries rely on working equids for transport/agriculture/mining. Therefore, the understanding of hoof conditions/shape variations affecting... Read More about Physics of animal health: on the mechano-biology of hoof growth and form.

Use of biologically active 3D matrix for extensive skin defect treatment in veterinary practice: case report (2019)
Journal Article

Objectives: Large full-thickness skin defects represent a serious veterinary problem. Methods: We have developed novel bioactive 3D-matrixes based on fibrin glue Tissucol (Baxter), containing the combination of the adenoviral constructs with genes v... Read More about Use of biologically active 3D matrix for extensive skin defect treatment in veterinary practice: case report.

Veterinary anatomy and physiology (2019)
Book

Knowledge of veterinary anatomy and physiology is essential for veterinary professionals and researchers. The chapters reflect the diverse and dynamic research being undertaken in a variety of different species throughout the world. Whether the anima... Read More about Veterinary anatomy and physiology.

Reptilian skin and its special histological structures (2019)
Book Chapter

Reptilian skin is covered with scales forming armor that makes it watertight and enables reptiles to live on land in contrast to amphibians. An important part of the skin is the horny epidermis, with thick stratum corneum in which waxes are arranged... Read More about Reptilian skin and its special histological structures.

Insight into imiquimod skin permeation and increased delivery using microneedle pre-treatment (2019)
Journal Article

Basal cell carcinoma (BCC) is the most common skin cancer in humans. Topical treatment with imiquimod provides a non-invasive, self-administered treatment with relatively low treatment cost. Despite displaying excellent efficacy, imiquimod is only li... Read More about Insight into imiquimod skin permeation and increased delivery using microneedle pre-treatment.

The Anatomy, Histology and Physiology of the Healthy and Lame Equine Hoof (2019)
Book Chapter

Satisfactory investigations of the equine foot appear to be limited by the histomorphological complexity of internal hoof structures. Foot lameness is considered to be one of the most debilitating pathological disorders of the equine foot. In most sp... Read More about The Anatomy, Histology and Physiology of the Healthy and Lame Equine Hoof.

Introductory Chapter: Veterinary Anatomy and Physiology (2019)
Book Chapter

Avian Cardiovascular Disease Characteristics, Causes and Genomics (2018)
Book Chapter

Cardiovascular disease is common in avian species and increasing commercial economic losses and demand for healthcare in the household/smallholding veterinary sector has resulted in increased research into these disorders. This in turn has highlighte... Read More about Avian Cardiovascular Disease Characteristics, Causes and Genomics.

Gene therapy using plasmid DNA encoding VEGF164 and FGF2 genes: a novel treatment of naturally occurring tendinitis and desmitis in horses (2018)
Journal Article

This clinical study describes the intralesional application of the plasmid DNA encoding two therapeutic species-specific growth factors: vascular endothelial growth factor (VEGF164) and fibroblast growth factor 2 (FGF2) in seven horses to restore nat... Read More about Gene therapy using plasmid DNA encoding VEGF164 and FGF2 genes: a novel treatment of naturally occurring tendinitis and desmitis in horses.