Epidemiology and risk factors of osteosarcoma

Sadykova, Leissan R; Ntekim, Atara I; Muyangwa-Semenova, Musalwa; Rutland, Catrin S; Jeyapalan, Jennie N; Blatt, Nataliya; Rizvanov, Albert

Abstract

Osteosarcoma is a rare tumor diagnosed at any age; however younger age is a common risk factor. In addition, multiple factors are believed to contribute to higher rates of osteosarcoma, particularly race and gender. Although diagnosed worldwide, osteosarcoma is found to be more prevalent in Africa with high numbers of cases reported in Nigeria, Uganda, and Sudan. Additionally, higher rates are detected in African Americans, suggesting a genetic predisposition linked to race. This review focuses on identifying high risk factors of osteosarcoma with an emphasis on sarcoma epidemiology and risk factors in African countries.

Citation

Sadykova, L. R., Ntekim, A. I., Muyangwa-Semenova, M., Rutland, C. S., Jeyapalan, J. N., Blatt, N., & Rizvanov, A. (2020). Epidemiology and risk factors of osteosarcoma. Cancer Investigation, 38(5), 259-269. https://doi.org/10.1080/07357907.2020.1768401

• Journal Article Type: Article
• Acceptance Date: May 9, 2020
• Online Publication Date: May 13, 2020
• Publication Date: 2020
• Deposit Date: May 11, 2020
• Publicly Available Date: May 14, 2021
• Journal: Cancer Investigation
• Print ISSN: 0735-7907
• Electronic ISSN: 1532-4192
• Publisher: Taylor & Francis Open
• Peer Reviewed: Peer Reviewed
• Volume: 38
• Issue: 5
• Pages: 259-269
• DOI: https://doi.org/10.1080/07357907.2020.1768401
• Keywords: Bone tumor; Epidemiology; Genetic markers; Pathogenesis; Mesenchymal stem
• Public URL: https://nottingham-repository.worktribe.com/output/4416346
• Publisher URL: https://www.tandfonline.com/doi/full/10.1080/07357907.2020.1768401
• Additional Information: Peer Review Statement: The publishing and review policy for this title is described in its Aims & Scope.; Aim & Scope: http://www.tandfonline.com/action/journalInformation?show=aimsScope&journalCode=icnv20; Received: 2020-03-26; Accepted: 2020-05-09; Published: 2020-05-13