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Epidemiology and risk factors of osteosarcoma

Sadykova, Leissan R; Ntekim, Atara I; Muyangwa-Semenova, Musalwa; Rutland, Catrin S; Jeyapalan, Jennie N; Blatt, Nataliya; Rizvanov, Albert

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Authors

Leissan R Sadykova

Atara I Ntekim

Musalwa Muyangwa-Semenova

Nataliya Blatt

Albert Rizvanov



Abstract

Osteosarcoma is a rare tumor diagnosed at any age; however younger age is a common risk factor. In addition, multiple factors are believed to contribute to higher rates of osteosarcoma, particularly race and gender. Although diagnosed worldwide, osteosarcoma is found to be more prevalent in Africa with high numbers of cases reported in Nigeria, Uganda, and Sudan. Additionally, higher rates are detected in African Americans, suggesting a genetic predisposition linked to race. This review focuses on identifying high risk factors of osteosarcoma with an emphasis on sarcoma epidemiology and risk factors in African countries.

Citation

Sadykova, L. R., Ntekim, A. I., Muyangwa-Semenova, M., Rutland, C. S., Jeyapalan, J. N., Blatt, N., & Rizvanov, A. (2020). Epidemiology and risk factors of osteosarcoma. Cancer Investigation, 38(5), 259-269. https://doi.org/10.1080/07357907.2020.1768401

Journal Article Type Article
Acceptance Date May 9, 2020
Online Publication Date May 13, 2020
Publication Date 2020
Deposit Date May 11, 2020
Publicly Available Date Mar 28, 2024
Journal Cancer Investigation
Print ISSN 0735-7907
Electronic ISSN 1532-4192
Publisher Taylor and Francis
Peer Reviewed Peer Reviewed
Volume 38
Issue 5
Pages 259-269
DOI https://doi.org/10.1080/07357907.2020.1768401
Keywords Bone tumor; Epidemiology; Genetic markers; Pathogenesis; Mesenchymal stem
Public URL https://nottingham-repository.worktribe.com/output/4416346
Publisher URL https://www.tandfonline.com/doi/full/10.1080/07357907.2020.1768401
Additional Information Peer Review Statement: The publishing and review policy for this title is described in its Aims & Scope.; Aim & Scope: http://www.tandfonline.com/action/journalInformation?show=aimsScope&journalCode=icnv20; Received: 2020-03-26; Accepted: 2020-05-09; Published: 2020-05-13

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