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Outputs (23)

Mucoadhesive chitosan-coated nanostructured lipid carriers for oral delivery of amphotericin B (2018)
Journal Article
Tan Sui Ling, J., Roberts, C., & Billa, N. (2018). Mucoadhesive chitosan-coated nanostructured lipid carriers for oral delivery of amphotericin B. Pharmaceutical Development and Technology, 24(4), 504-512. https://doi.org/10.1080/10837450.2018.1515225

This study describes the properties of an amphotericin B-containing mucoadhesive nanostructured lipid carrier (NLC), with the intent to maximize uptake within the gastrointestinal tract. We have reported previously that lipid nanoparticles can signif... Read More about Mucoadhesive chitosan-coated nanostructured lipid carriers for oral delivery of amphotericin B.

Antifungal and mucoadhesive properties of an orally administered chitosan-coated amphotericin B 1 nanostructured lipid carrier (NLC) (2019)
Journal Article
Ling, J. T. S., Roberts, C., & Billa, N. (2019). Antifungal and mucoadhesive properties of an orally administered chitosan-coated amphotericin B 1 nanostructured lipid carrier (NLC). AAPS PharmSciTech, 20(3), Article 136. https://doi.org/10.1208/s12249-019-1346-7

Surface - modified nanostructured lipid carriers (NLC) is a promising formulation to prolong the retention time of the therapeutic agent at the site of absorption. Chitosan-coated AmpB-loaded NLC (ChiAmpB NLC) were developed showing particle size of... Read More about Antifungal and mucoadhesive properties of an orally administered chitosan-coated amphotericin B 1 nanostructured lipid carrier (NLC).

Education Program for Carers in Facilities with Neuro Disabled Subjects EPoCFiNDS (2019)
Journal Article
Dionyssiotis, Y., Vellidou, E., Konstantinidis, S. T., Sarafis, P., Artemi, S., Stergiopoulou, K., …Koutsouris, D. (2019). Education Program for Carers in Facilities with Neuro Disabled Subjects EPoCFiNDS. Journal of Frailty, Sarcopenia and Falls, 4(2), 45-50. https://doi.org/10.22540/JFSF-04-045

The prevalence of chronic illness and the disabilities they cause are strongly associated with age. According to the United Nations, in most countries around the world, 8-10% of the population has some form of disability. Carers are helping subject... Read More about Education Program for Carers in Facilities with Neuro Disabled Subjects EPoCFiNDS.

Stem cells from the dental apical papilla in extracellular matrix hydrogels mitigate inflammation of microglial cells (2019)
Journal Article
Tatic, N., Rose, F. R., des Rieux, A., & White, L. J. (2019). Stem cells from the dental apical papilla in extracellular matrix hydrogels mitigate inflammation of microglial cells. Scientific Reports, 9, Article 14015. https://doi.org/10.1038/s41598-019-50367-x

After spinal cord injury (SCI) chronic inflammation hampers regeneration. Influencing the local microenvironment after SCI may provide a strategy to modulate inflammation and the immune response. The objectives of this work were to determine whether... Read More about Stem cells from the dental apical papilla in extracellular matrix hydrogels mitigate inflammation of microglial cells.

A Global Comparison of Initial Pharmacy Education Curricula: An Exploratory Study (2020)
Journal Article
Arakawa, N., Bruno, A., & Bates, I. (2020). A Global Comparison of Initial Pharmacy Education Curricula: An Exploratory Study. INNOVATIONS in Pharmacy, 11(1), Article 18. https://doi.org/10.24926/iip.v11i1.2093

Background: Time-tabled curricular contents and syllabi reflect the actual delivery of the academic programme and one of key quality components in healthcare professional education. There is a need of global evidence base of Initial Pharmacy Educatio... Read More about A Global Comparison of Initial Pharmacy Education Curricula: An Exploratory Study.

Using Internet of Things to Reduce Office Workers’ Sedentary Behavior: Intervention Development Applying the Behavior Change Wheel and Human-Centered Design Approach (2020)
Journal Article
Huang, Y., Benford, S., Price, D., Patel, R., Li, B., Ivanov, A., & Blake, H. (2020). Using Internet of Things to Reduce Office Workers’ Sedentary Behavior: Intervention Development Applying the Behavior Change Wheel and Human-Centered Design Approach. JMIR mHealth and uHealth, 8(7), Article e17914. https://doi.org/10.2196/17914

Background: Sedentary behavior (SB) is associated with various adverse health outcomes. The prevalence of prolonged sitting at work among office workers makes a case for SB interventions to target this setting and population. Everyday mundane objects... Read More about Using Internet of Things to Reduce Office Workers’ Sedentary Behavior: Intervention Development Applying the Behavior Change Wheel and Human-Centered Design Approach.

WHIRL Study: Workplace Health Interprofessional Learning in the Construction Industry (2020)
Journal Article
Blake, H., Somerset, S., Whittingham, K., Middleton, M., Yildirim, M., & Evans, C. (2020). WHIRL Study: Workplace Health Interprofessional Learning in the Construction Industry. International Journal of Environmental Research and Public Health, 17(18), Article 6815. https://doi.org/10.3390/ijerph17186815

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Interprofessional learning (IPL) is essential to prepare healthcare trainees as the future public health workforce. WHIRL (Workplace Health InteRprofessional Learning) was an innovative IPL in... Read More about WHIRL Study: Workplace Health Interprofessional Learning in the Construction Industry.

Test@Work Texts: Mobile Phone Messaging to Increase Awareness of HIV and HIV Testing in UK Construction Employees during the COVID-19 Pandemic (2020)
Journal Article
Middleton, M., Somerset, S., Evans, C., & Blake, H. (2020). Test@Work Texts: Mobile Phone Messaging to Increase Awareness of HIV and HIV Testing in UK Construction Employees during the COVID-19 Pandemic. International Journal of Environmental Research and Public Health, 17(21), Article 7819. https://doi.org/10.3390/ijerph17217819

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Background: HIV poses a threat to global health. With effective treatment options available, education and testing strategies are essential in preventing transmission. Text messaging is an eff... Read More about Test@Work Texts: Mobile Phone Messaging to Increase Awareness of HIV and HIV Testing in UK Construction Employees during the COVID-19 Pandemic.

COVID-Well: Evaluation of the Implementation of Supported Wellbeing Centres for Hospital Employees during the COVID-19 Pandemic (2020)
Journal Article
Blake, H., Yildirim, M., Wood, B., Knowles, S., Mancini, H., Coyne, E., & Cooper, J. (2020). COVID-Well: Evaluation of the Implementation of Supported Wellbeing Centres for Hospital Employees during the COVID-19 Pandemic. International Journal of Environmental Research and Public Health, 17(24), 1-22. https://doi.org/10.3390/ijerph17249401

Supported Wellbeing Centres have been set up in UK hospital trusts in an effort to mitigate the psychological impact of COVID-19 on healthcare workers, although the extent to which these are utilised and the barriers and facilitators to access are no... Read More about COVID-Well: Evaluation of the Implementation of Supported Wellbeing Centres for Hospital Employees during the COVID-19 Pandemic.

Covid-well study: Qualitative evaluation of supported wellbeing centres and psychological first aid for healthcare workers during the covid-19 pandemic (2021)
Journal Article
Blake, H., Gupta, A., Javed, M., Wood, B., Knowles, S., Coyne, E., & Cooper, J. (2021). Covid-well study: Qualitative evaluation of supported wellbeing centres and psychological first aid for healthcare workers during the covid-19 pandemic. International Journal of Environmental Research and Public Health, 18(7), Article 3626. https://doi.org/10.3390/ijerph18073626

Supported wellbeing centres were set up in UK hospital trusts as an early intervention aimed at mitigating the psychological impact of COVID-19 on healthcare workers. These provided high quality rest spaces with peer-to-peer psychological support pro... Read More about Covid-well study: Qualitative evaluation of supported wellbeing centres and psychological first aid for healthcare workers during the covid-19 pandemic.

Development of a school-based intervention to increase physical activity levels among Chinese children: a systematic iterative process based on Behaviour Change Wheel and Theoretical Domains Framework (2021)
Journal Article
Chattopadhyay, K., Blake, H., & Wang, H. (2021). Development of a school-based intervention to increase physical activity levels among Chinese children: a systematic iterative process based on Behaviour Change Wheel and Theoretical Domains Framework. Frontiers in Public Health, 9, Article 610245. https://doi.org/10.3389/fpubh.2021.610245

Regular physical activity has a range of benefits for children’s health, academic achievement, and behavioral development, yet they face barriers to participation. The aim of the study was to systematically develop an intervention for improving Chine... Read More about Development of a school-based intervention to increase physical activity levels among Chinese children: a systematic iterative process based on Behaviour Change Wheel and Theoretical Domains Framework.

Accessing Voluntary HIV Testing in the Construction Industry: A Qualitative Analysis of Employee Interviews from the Test@Work Study (2021)
Journal Article
Somerset, S., Evans, C., & Blake, H. (2021). Accessing Voluntary HIV Testing in the Construction Industry: A Qualitative Analysis of Employee Interviews from the Test@Work Study. International Journal of Environmental Research and Public Health, 18(8), Article 4184. https://doi.org/10.3390/ijerph18084184

HIV, globally, remains a significant public health issue and community HIV testing can help to identify those with HIV at an early stage of disease. The workplace offers a prime location for provision of opt-in HIV testing as part of wider health pro... Read More about Accessing Voluntary HIV Testing in the Construction Industry: A Qualitative Analysis of Employee Interviews from the Test@Work Study.

Characterising the outcomes, impacts and implementation challenges of advanced clinical practice roles in the UK: A scoping review (2021)
Journal Article
Evans, C., Poku, B. A., Pearce, R., Eldridge, J., Hendrick, P., Knaggs, R., …Collier, R. (2021). Characterising the outcomes, impacts and implementation challenges of advanced clinical practice roles in the UK: A scoping review. BMJ Open, 11(8), Article e048171. https://doi.org/10.1136/bmjopen-2020-048171

Objectives In response to demographic and health system pressures, the development of non-medical advanced clinical practice (ACP) roles is a key component of National Health Service workforce transformation policy in the UK. This review was undertak... Read More about Characterising the outcomes, impacts and implementation challenges of advanced clinical practice roles in the UK: A scoping review.

Test@work: evaluation of workplace HIV testing for construction workers using the RE-AIM framework (2021)
Journal Article
Jones, W., Somerset, S., Evans, C., Whittingham, K., Middleton, M., & Blake, H. (2021). Test@work: evaluation of workplace HIV testing for construction workers using the RE-AIM framework. BMC Public Health, 21, Article 1737. https://doi.org/10.1186/s12889-021-11739-z

Background: Community testing for HIV can reach previously untested populations but is rarely offered in workplaces. Targeting the construction sector could reach workers from high risk populations. Methods: The RE-AIM framework was used to evaluate... Read More about Test@work: evaluation of workplace HIV testing for construction workers using the RE-AIM framework.

Psychological Impacts of COVID–19 on Healthcare Trainees and Perceptions towards a Digital Wellbeing Support Package (2021)
Journal Article
Blake, H., Mahmood, I., Dushi, G., Yildirim, M., & Gay, E. (2021). Psychological Impacts of COVID–19 on Healthcare Trainees and Perceptions towards a Digital Wellbeing Support Package. International Journal of Environmental Research and Public Health, 18(20), Article 10647. https://doi.org/10.3390/ijerph182010647

We explore the impact of COVID-19 on the psychological wellbeing of healthcare trainees, and the perceived value of a digital support package to mitigate the psychological impacts of the pandemic (PoWerS Study). This mixed–methods study includes (i)... Read More about Psychological Impacts of COVID–19 on Healthcare Trainees and Perceptions towards a Digital Wellbeing Support Package.

The effect of stimulus duration on preferences for gain adjustments when listening to speech (2021)
Journal Article
Whitmer, W. M., Caswell-Midwinter, B., & Naylor, G. (2022). The effect of stimulus duration on preferences for gain adjustments when listening to speech. International Journal of Audiology, 61(11), 940-947. https://doi.org/10.1080/14992027.2021.1998676

Objectives: In the personalisation of hearing-aid fittings, gain is often adjusted to suit patient preferences using live speech. When using brief sentences as stimuli, the minimum gain adjustments necessary to elicit consistent preferences (“prefere... Read More about The effect of stimulus duration on preferences for gain adjustments when listening to speech.

Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content (2022)
Journal Article
Taylor, M., Simoes, F., Smith, J., Genapathy, S., Canning, A., Lledos, M., …Zelzer, M. (2022). Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content. Surface and Interface Analysis, 54(4), 417-432. https://doi.org/10.1002/sia.7052

Peptide-coated surfaces are widely employed in biomaterial design, but quantifiable correlation between surface composition and biological response is challenging due to, for example, instrumental limitations, a lack of suitable model surfaces or lim... Read More about Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content.

Controlled release of MT-1207 using a novel gastroretentive bilayer system comprised of hydrophilic and hydrophobic polymers (2023)
Journal Article
Vrettos, N., Wang, P., Wang, Y., Roberts, C. J., Xu, J., Yao, H., & Zhu, Z. (2023). Controlled release of MT-1207 using a novel gastroretentive bilayer system comprised of hydrophilic and hydrophobic polymers. Pharmaceutical Development and Technology, 28(8), 724-742. https://doi.org/10.1080/10837450.2023.2238822

In the present study, novel gastroretentive bilayer tablets were developed that are promising for the once-a-day oral delivery of the drug candidate MT-1207. The gastroretentive layer consisted of a combination of hydrophilic and hydrophobic polymers... Read More about Controlled release of MT-1207 using a novel gastroretentive bilayer system comprised of hydrophilic and hydrophobic polymers.