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Avian Cardiovascular Disease Characteristics, Causes and Genomics

Kubale, Valentina; Merry, Keshia; Miller, Georgia; Ruiz Diaz, Maria; Rutland, Catrin

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Authors

Valentina Kubale

Keshia Merry

Georgia Miller

Maria Ruiz Diaz



Contributors

Xiaojun Liu
Editor

Abstract

Cardiovascular disease is common in avian species and increasing commercial economic losses and demand for healthcare in the household/smallholding veterinary sector has resulted in increased research into these disorders. This in turn has highlighted the importance of breeding, genetic testing and possibilities for future prognostic and diagnostic testing. Research into avian cardiovascular genetics has rapidly accelerated. Previously much work was undertaken in mammals with information extrapolated and transferred to birds. Birds have also been used to model cardiovascular disease and therefore knowledge has become enriched due to this endeavour. Increasingly, the avian genome is being analysed in its own right. This work is assisted by the growing number of avian genomes being published. In 2015, Nature published news on the ‘Bird 10K’ project, which aims to sequence 10,500 extant bird species. By 2018, the Avian Genomes Consortium had published the sequences of 45 species/34 orders. This review investigates a range of avian cardiovascular disorders in order to highlight their pathologies, epidemiology and genetics in addition to avian models of heart disease. With the availability of more reference genomes, increases in the number and magnitude of avian studies and more advanced technologies, the genetics behind avian cardiovascular disorders is being unravelled.

Citation

Kubale, V., Merry, K., Miller, G., Ruiz Diaz, M., & Rutland, C. (2018). Avian Cardiovascular Disease Characteristics, Causes and Genomics. In X. Liu (Ed.), Application of genetics and genomics in poultry science (141-162). London: InTech. https://doi.org/10.5772/intechopen.78005

Acceptance Date Apr 27, 2018
Online Publication Date Sep 5, 2018
Publication Date Sep 5, 2018
Deposit Date Sep 6, 2018
Publicly Available Date Mar 29, 2024
Publisher InTech
Pages 141-162
Book Title Application of genetics and genomics in poultry science
Chapter Number 9
ISBN 9781789236316
DOI https://doi.org/10.5772/intechopen.78005
Public URL https://nottingham-repository.worktribe.com/output/1062802
Publisher URL https://www.intechopen.com/books/application-of-genetics-and-genomics-in-poultry-science/avian-cardiovascular-disease-characteristics-causes-and-genomics

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