All Outputs (16)

Ink-jet 3D printing as a strategy for developing bespoke non-eluting biofilm resistant medical devices (2021)
Journal Article
He, Y., Luckett, J., Begines, B., Dubern, J. F., Hook, A. L., Prina, E., …Wildman, R. D. (2022). Ink-jet 3D printing as a strategy for developing bespoke non-eluting biofilm resistant medical devices. Biomaterials, 281, Article 121350. https://doi.org/10.1016/j.biomaterials.2021.121350

Chronic infection as a result of bacterial biofilm formation on implanted medical devices is a major global healthcare problem requiring new biocompatible, biofilm-resistant materials. Here we demonstrate how bespoke devices can be manufactured throu... Read More about Ink-jet 3D printing as a strategy for developing bespoke non-eluting biofilm resistant medical devices.

The influence of printing parameters on multi-material two-photon polymerisation based micro additive manufacturing (2021)
Journal Article
Hu, Q., Rance, G. A., Trindade, G. F., Pervan, D., Jiang, L., Foerster, A., …Wildman, R. D. (2022). The influence of printing parameters on multi-material two-photon polymerisation based micro additive manufacturing. Additive Manufacturing, 51, Article 102575. https://doi.org/10.1016/j.addma.2021.102575

Two-photon polymerisation (2PP) based additive manufacturing has emerged as a powerful technology to fabricate complex three-dimensional micro- and nanoscale architectures. However, a comprehensive understanding of the effect of printing parameters o... Read More about The influence of printing parameters on multi-material two-photon polymerisation based micro additive manufacturing.

Application of microfluidic systems in modelling impacts of environmental structure on stress-sensing by individual microbial cells (2021)
Journal Article
Harvey, H. J., Chubynsky, M. V., Sprittles, J. E., Shor, L. M., Mooney, S. J., Wildman, R. D., & Avery, S. V. (2022). Application of microfluidic systems in modelling impacts of environmental structure on stress-sensing by individual microbial cells. Computational and Structural Biotechnology Journal, 20, 128-138. https://doi.org/10.1016/j.csbj.2021.11.039

Environmental structure describes physical structure that can determine heterogenous spatial distribution of biotic and abiotic (nutrients, stressors etc.) components of a microorganism's microenvironment. This study investigated the impact of microm... Read More about Application of microfluidic systems in modelling impacts of environmental structure on stress-sensing by individual microbial cells.

Exploiting the fundamentals of biological organization for the advancement of biofabrication (2021)
Journal Article
Hill, J., Wildman, R., & Mata, A. (2022). Exploiting the fundamentals of biological organization for the advancement of biofabrication. Current Opinion in Biotechnology, 74, 42-54. https://doi.org/10.1016/j.copbio.2021.10.016

The field of biofabrication continues to progress, offering higher levels of spatial control, reproducibility, and functionality. However, we remain far from recapitulating what nature has achieved. Biological systems such as tissues and organs are a... Read More about Exploiting the fundamentals of biological organization for the advancement of biofabrication.

Customisable Tablet Printing: The Development of Multimaterial Hot Melt Inkjet 3D Printing to Produce Complex and Personalised Dosage Forms (2021)
Journal Article
Lion, A., Wildman, R. D., Alexander, M. R., & Roberts, C. J. (2021). Customisable Tablet Printing: The Development of Multimaterial Hot Melt Inkjet 3D Printing to Produce Complex and Personalised Dosage Forms. Pharmaceutics, 13(10), Article 1679. https://doi.org/10.3390/pharmaceutics13101679

One of the most striking characteristics of 3D printing is its capability to produce multi-material objects with complex geometry. In pharmaceutics this translates to the possibility of dosage forms with multi-drug loading, tailored dosing and releas... Read More about Customisable Tablet Printing: The Development of Multimaterial Hot Melt Inkjet 3D Printing to Produce Complex and Personalised Dosage Forms.

A new particle mounting method for surface analysis (2021)
Journal Article
Dundas, A. A., Kern, S., Cuzzucoli Crucitti, V., Scurr, D. J., Wildman, R., Irvine, D. J., & Alexander, M. R. (2022). A new particle mounting method for surface analysis. Surface and Interface Analysis, 54(4), 374-380. https://doi.org/10.1002/sia.7010

The chemical analysis of microparticles is challenging due to the need to mount the particles on a substrate for analysis; double-sided adhesive tape is often used (sometimes conductive), however that is usually coated with poly (dimethyl siloxane) (... Read More about A new particle mounting method for surface analysis.

Generation and Characterization of a Library of Novel Biologically Active Functional Surfactants (Surfmers) Using Combined High-Throughput Methods (2021)
Journal Article
Cuzzucoli Crucitti, V., Contreas, L., Taresco, V., Howard, S. C., Dundas, A. A., Limo, M. J., …Irvine, D. J. (2021). Generation and Characterization of a Library of Novel Biologically Active Functional Surfactants (Surfmers) Using Combined High-Throughput Methods. ACS Applied Materials and Interfaces, 13(36), 43290-43300. https://doi.org/10.1021/acsami.1c08662

We report the first successful combination of three distinct high-throughput techniques to deliver the accelerated design, synthesis, and property screening of a library of novel, bio-instructive, polymeric, comb-graft surfactants. These three-dimens... Read More about Generation and Characterization of a Library of Novel Biologically Active Functional Surfactants (Surfmers) Using Combined High-Throughput Methods.

Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers (2021)
Journal Article
Ruiz-Cantu, L., Trindade, G. F., Taresco, V., Zhou, Z., He, Y., Burroughs, L., …Wildman, R. D. (2021). Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers. ACS Applied Materials and Interfaces, 13(33), 38969-38978. https://doi.org/10.1021/acsami.1c07850

Controlling the microstructure of materials by means of phase separation is a versatile tool for optimizing material properties. Phase separation has been exploited to fabricate intricate microstructures in many fields including cell biology, tissue... Read More about Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers.

Evaluation of photoanode materials used in biophotovoltaic systems for renewable energy generation (2021)
Journal Article
Anam, M., Gomes, H. I., Rivers, G., Gomes, R. L., & Wildman, R. (2021). Evaluation of photoanode materials used in biophotovoltaic systems for renewable energy generation. Sustainable Energy and Fuels, 5(17), 4209-4232. https://doi.org/10.1039/d1se00396h

Biological photovoltaic (BPV) cells are living solar panels capable of producing clean energy by extracting electrons from sunlight (in daytime) and stored carbon in microbial cells (during the night or on cloudy days), irrespective of the organic su... Read More about Evaluation of photoanode materials used in biophotovoltaic systems for renewable energy generation.

Microbial Metal Resistance within Structured Environments Is Inversely Related to Environmental Pore Size (2021)
Journal Article
Harvey, H. J., Mitzakoff, A. M., Wildman, R. D., Mooney, S. J., & Avery, S. V. (2021). Microbial Metal Resistance within Structured Environments Is Inversely Related to Environmental Pore Size. Applied and Environmental Microbiology, 87(20), Article e01005-21. https://doi.org/10.1128/AEM.01005-21

The physical environments in which microorganisms naturally reside rarely have homogeneous structure, and changes in their porous architecture may have effects on microbial activities that are not typically captured in conventional laboratory studies... Read More about Microbial Metal Resistance within Structured Environments Is Inversely Related to Environmental Pore Size.

Poly (glycerol adipate) (PGA) backbone modifications with a library of functional diols: Chemical and physical effects (2021)
Journal Article
Jacob, P. L., Ruiz Cantu, L. A., Pearce, A. K., He, Y., Lentz, J. C., Moore, J. C., …Taresco, V. (2021). Poly (glycerol adipate) (PGA) backbone modifications with a library of functional diols: Chemical and physical effects. Polymer, 228, Article 123912. https://doi.org/10.1016/j.polymer.2021.123912

Enzymatically synthesised poly(glycerol adipate) (PGA) has shown a palette of key desirable properties required for a biomaterial to be considered a ‘versatile polymeric tool’ in the field of drug delivery. PGA and its variations can self-assemble in... Read More about Poly (glycerol adipate) (PGA) backbone modifications with a library of functional diols: Chemical and physical effects.

Droplet Microfluidic Optimisation Using Micropipette Characterisation of Bio-Instructive Polymeric Surfactants (2021)
Journal Article
Henshaw, C. A., Dundas, A. A., Cuzzucoli Crucitti, V., Alexander, M. R., Wildman, R., Rose, F. R. A. J., …Williams, P. M. (2021). Droplet Microfluidic Optimisation Using Micropipette Characterisation of Bio-Instructive Polymeric Surfactants. Molecules, 26(11), Article 3302. https://doi.org/10.3390/molecules26113302

Droplet microfluidics can produce highly tailored microparticles whilst retaining monodispersity. However, these systems often require lengthy optimisation, commonly based on a trial-and-error approach, particularly when using bio-instructive, polyme... Read More about Droplet Microfluidic Optimisation Using Micropipette Characterisation of Bio-Instructive Polymeric Surfactants.

Residual polymer stabiliser causes anisotropic electrical conductivity during inkjet printing of metal nanoparticles (2021)
Journal Article
Trindade, G. F., Wang, F., Im, J., He, Y., Balogh, A., Scurr, D., …Roberts, C. J. (2021). Residual polymer stabiliser causes anisotropic electrical conductivity during inkjet printing of metal nanoparticles. Communications Materials, 2(1), Article 47. https://doi.org/10.1038/s43246-021-00151-0

Inkjet printing of metal nanoparticles allows for design flexibility, rapid processing and enables the 3D printing of functional electronic devices through co-deposition of multiple materials. However, the performance of printed devices, especially t... Read More about Residual polymer stabiliser causes anisotropic electrical conductivity during inkjet printing of metal nanoparticles.

Inkjet 3D Printing of Polymers Resistant to Fungal Attachment (2021)
Journal Article
He, Y., Vallières, C., Alexander, M. R., Wildman, R. D., & Avery, S. V. (2021). Inkjet 3D Printing of Polymers Resistant to Fungal Attachment. Bio-protocol, 11(9), Article e4016. https://doi.org/10.21769/BioProtoc.4016

Inkjet 3D printing is an additive manufacturing method that allows the user to produce a small batch of customized devices for comparative study versus commercial products. Here, we describe the use of a commercial 2D ink development system (Dimatix... Read More about Inkjet 3D Printing of Polymers Resistant to Fungal Attachment.

UV-curable silicone materials with tuneable mechanical properties for 3D Printing (2021)
Journal Article
Foerster, A., Annarasa, V., Terry, A., Wildman, R., Hague, R., Irvine, D., …Tuck, C. (2021). UV-curable silicone materials with tuneable mechanical properties for 3D Printing. Materials and Design, Article 109681. https://doi.org/10.1016/j.matdes.2021.109681

In this paper, we present the development of a family of novel, UV-curable, highly flexible, 3D printable silicone-based materials, the mechanical properties of which can be tuned simply by varying the ratio of the polymerisable reagents within the f... Read More about UV-curable silicone materials with tuneable mechanical properties for 3D Printing.

3D printed polymeric drug-eluting implants (2021)
Journal Article
Liaskoni, A., Wildman, R. D., & Roberts, C. J. (2021). 3D printed polymeric drug-eluting implants. International Journal of Pharmaceutics, 597, Article 120330. https://doi.org/10.1016/j.ijpharm.2021.120330

An extrusion-based 3D printer has been used for the manufacturing of sustained drug release poly(ε-caprolactone) (PCL) implants. Such implants can address issues of reduced patient compliance due to the necessary frequent administration of convention... Read More about 3D printed polymeric drug-eluting implants.