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Inkjet 3D Printing of Polymers Resistant to Fungal Attachment

He, Yinfeng; Valli�res, Cindy; Alexander, Morgan R.; Wildman, Ricky D.; Avery, Simon V.

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Authors

YINFENG HE Yinfeng.He@nottingham.ac.uk
Transitional Assistant Professor

Cindy Valli�res

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MORGAN ALEXANDER MORGAN.ALEXANDER@NOTTINGHAM.AC.UK
Professor of Biomedical Surfaces

RICKY WILDMAN RICKY.WILDMAN@NOTTINGHAM.AC.UK
Professor of Multiphase Flow and Mechanics

SIMON AVERY SIMON.AVERY@NOTTINGHAM.AC.UK
Professor of Eukaryotic Microbiology



Abstract

Inkjet 3D printing is an additive manufacturing method that allows the user to produce a small batch of customized devices for comparative study versus commercial products. Here, we describe the use of a commercial 2D ink development system (Dimatix material printing) to manufacture small batches of 3D medical or other devices using a recentlycharacterized fungal anti-attachment material. Such printed devices may resist problems that beset commercial medical products due to colonization by the fungal pathogen Candida albicans. By sequentially introducing the cross-section bitmapsof the product's CAD model and elevating the print head height usingthe auto-clicking script, we were able to createcomplex self-support geometries with the 2D ink development system. The use of this protocol allows researchers to produce a small batch of specimens for characterization fromonly a few grams of raw material. Additionally, wedescribe the testing of manufactured specimens for fungal anti-attachment. In comparisonwith most commercial AM systems, which require at least a few hundred grams ofink for printing trials, our protocol is well suited for smaller-scale production in material studies.

Citation

He, Y., Vallières, C., Alexander, M. R., Wildman, R. D., & Avery, S. V. (2021). Inkjet 3D Printing of Polymers Resistant to Fungal Attachment. Bio-protocol, 11(9), Article e4016. https://doi.org/10.21769/BioProtoc.4016

Journal Article Type Article
Acceptance Date Mar 24, 2021
Online Publication Date May 5, 2021
Publication Date May 5, 2021
Deposit Date Mar 24, 2021
Publicly Available Date May 18, 2021
Journal Bio-protocol
Electronic ISSN 2331-8325
Publisher Bio-Protocol
Peer Reviewed Peer Reviewed
Volume 11
Issue 9
Article Number e4016
DOI https://doi.org/10.21769/BioProtoc.4016
Public URL https://nottingham-repository.worktribe.com/output/5413298
Publisher URL https://bio-protocol.org/e4016

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