All Outputs (663)

Isolation and characterization of oil bodies from Oryza sativa bran and studies of their physical properties (2012)
Journal Article

In this paper, we demonstrate a novel and environmentally-conscious approach to the isolation of oil bodies (OBs) from the bran arising from the milling of Oryza sativa (Basmati rice). We have used several physical techniques to determine the effect... Read More about Isolation and characterization of oil bodies from Oryza sativa bran and studies of their physical properties.

Electrospun PLGA fibre sheets incorporating fluorescent nanosensors: Self-reporting scaffolds for application in tissue engineering (2012)
Journal Article

Ratiometric analyte responsive nanosensors have been incorporated into electrospun poly(lactic-co-glycolic) acid (PLGA) fibres to create self-reporting scaffolds. It has been demonstrated that the self-reporting scaffolds could be utilised to monitor... Read More about Electrospun PLGA fibre sheets incorporating fluorescent nanosensors: Self-reporting scaffolds for application in tissue engineering.

Academic patenting: the importance of industry support (2012)
Journal Article

This paper provides evidence that university-industry collaboration is important for turning commercial opportunities into patents. The results suggest that researchers who receive a large share of research grants from industry have a higher propensi... Read More about Academic patenting: the importance of industry support.

Pathway to cryogen free production of hyperpolarized krypton-83 and xenon-129 (2012)
Journal Article

yperpolarized (hp) 129Xe and hp 83Kr for magnetic resonance imaging (MRI) are typically obtained through spin-exchange optical pumping (SEOP) in gas mixtures with dilute concentrations of the respective noble gas. The usage of dilute noble gases mix... Read More about Pathway to cryogen free production of hyperpolarized krypton-83 and xenon-129.

Genome analysis of a simultaneously predatory and prey-independent, novel Bdellovibrio bacteriovorus from the River Tiber, supports in silico predictions of both ancient and recent lateral gene transfer from diverse bacteria (2012)
Journal Article

Background: Evolution equipped Bdellovibrio bacteriovorus predatory bacteria to invade other bacteria, digesting and replicating, sealed within them thus preventing nutrient-sharing with organisms in the surrounding environment. Bdellovibrio were... Read More about Genome analysis of a simultaneously predatory and prey-independent, novel Bdellovibrio bacteriovorus from the River Tiber, supports in silico predictions of both ancient and recent lateral gene transfer from diverse bacteria.

Ethnobiology: The missing link in ecology and evolution (2012)
Journal Article

Evolutionary biologists and ecologists increasingly appreciate the value of local knowledge of human communities for research into the past, present, and future of biodiversity. However, there are often significant problems accessing and interpreting... Read More about Ethnobiology: The missing link in ecology and evolution.

Herbert Hill and the Federal Bureau of Investigation (2012)
Journal Article

This article points to previously undetected evidence demonstrating that Herbert Hill, labor director of the National Association for the Advancement of Colored People (NAACP) from the 1950s to the 1970s, informed for the Federal Bureau of Investigat... Read More about Herbert Hill and the Federal Bureau of Investigation.

Primary liver cancer incidence and survival in ethnic groups in England, 2001-2007 (2012)
Journal Article

Background: The patterns of primary liver cancer incidence and survival are not known for detailed ethnic groups within the UK. Methods: Data on patients resident in England diagnosed with primary liver cancer (ICD-10 C22) between 2001 and 2007 w... Read More about Primary liver cancer incidence and survival in ethnic groups in England, 2001-2007.

Bridging the gap: bitopic ligands of G-protein-coupled receptors (2012)
Journal Article

Although classical approaches to G-protein-coupled receptor (GPCR) drug design have targeted the orthosteric binding site, potentially all GPCRs possess druggable allosteric sites. In addition, it is clear that GPCRs can adopt multiple active states... Read More about Bridging the gap: bitopic ligands of G-protein-coupled receptors.

Clusterin regulates beta-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway (2012)
Journal Article

Although the mechanism of Abaction in the pathogenesis of Alzheimer’s disease (AD) has remained elusive, it is known to increasethe expression of the antagonist of canonical wnt signalling, Dickkopf-1 (Dkk1), whereas the silencing ofDkk1blocks Abneur... Read More about Clusterin regulates beta-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway.

Leukotriene B4 receptor locus gene characterisation and association studies in asthma (2012)
Journal Article

Background: Polymorphisms spanning genes involved in the production of leukotriene B4 (LTB4) e.g. ALOX5AP and LTA4H are associated with asthma susceptibility, suggesting a role for LTB4 in disease. The contribution of LTB4 receptor polymorphism is... Read More about Leukotriene B4 receptor locus gene characterisation and association studies in asthma.

Adaptation for protein synthesis efficiency in a naturally occurring self-regulating operon (2012)
Journal Article

The korAB operon in RK2 plasmids is a beautiful natural example of a negatively and cooperatively self-regulating operon. It has been particularly well characterized both experimentally and with mathematical models. We have carried out a detailed inv... Read More about Adaptation for protein synthesis efficiency in a naturally occurring self-regulating operon.

p63 the guardian of human reproduction (2012)
Journal Article

p63 is a transcriptional factor implicated in cancer and development. The presence in TP63 gene of alternative promoters allows expression of one isoform containing the N-terminal transactivation domain (TA isoform) and one N-terminal truncated isofo... Read More about p63 the guardian of human reproduction.

PASCal: a principal axis strain calculator for thermal expansion and compressibility determination (2012)
Journal Article

This article describes a web-based tool (PASCal; principal axis strain calculator; http://pascal.chem.ox.ac.uk) designed to simplify the determination of principal coefficients of thermal expansion and compressibilities from variable-temperature and... Read More about PASCal: a principal axis strain calculator for thermal expansion and compressibility determination.

Heart rate variability and target organ damage in hypertensive patients (2012)
Journal Article

Background We evaluated the association between linear standard Heart Rate Variability (HRV) measures and vascular, renal and cardiac target organ damage (TOD). Methods A retrospective analysis was performed including 200 patients registered in... Read More about Heart rate variability and target organ damage in hypertensive patients.

Next generation sequencing of CLU, PICALM and CR1: pitfalls and potential solutions (2012)
Journal Article

CLU, PICALM and CR1 were identified as genetic risk factors for late onset Alzheimer’s disease (AD) in two large genome wide association studies (GWAS) published in 2009, but the variants that convey this alteration in disease risk, and how the genes... Read More about Next generation sequencing of CLU, PICALM and CR1: pitfalls and potential solutions.

Calibrated BOLD using direct measurement of changes in venous oxygenation (2012)
Journal Article

Calibration of the BOLD signal is potentially of great value in providing a closer measure of the underlying changes in brain function related to neuronal activity than the BOLD signal alone, but current approaches rely on an assumed relationship bet... Read More about Calibrated BOLD using direct measurement of changes in venous oxygenation.

Contribution of large scale biases in decoding of direction-of-motion from high-resolution fMRI data in human early visual cortex (2012)
Journal Article

Previous studies have demonstrated that the perceived direction of motion of a visual stimulus can be decoded from the pattern of functional magnetic resonance imaging (fMRI) responses in occipital cortex using multivariate analysis methods (Kamitani... Read More about Contribution of large scale biases in decoding of direction-of-motion from high-resolution fMRI data in human early visual cortex.

Transient serum exposure regimes to support dual differentiation of human mesenchymal stem cells (2012)
Journal Article

Human mesenchymal stem cells (MSCs), which can generate both osteoblasts and chondrocytes, represent an ideal resource for orthopaedic repair using tissue-engineering approaches. One major difficulty for the development of osteochondral constructs us... Read More about Transient serum exposure regimes to support dual differentiation of human mesenchymal stem cells.

Implications of regional surface ozone increases on visibility degradation in southeast China (2012)
Journal Article

Long-term visibility (1968–2010) and air pollutant (1984–2010) data records in Hong Kong reveal that the occurrence of reduced visibility (RV, defined as the percentage of hours per month with visibility below 8 km in the absence of rain, fog, mist o... Read More about Implications of regional surface ozone increases on visibility degradation in southeast China.