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Heart rate variability and target organ damage in hypertensive patients

Melillo, Paolo; Izzo, Raffaele; De Luca, Nicola; Pecchia, Leandro

Authors

Paolo Melillo paolo.melillo@unina.it

Raffaele Izzo

Nicola De Luca

Leandro Pecchia Leandro.Pecchia@nottingham.ac.uk

Abstract

Background
We evaluated the association between linear standard Heart Rate Variability (HRV) measures and vascular, renal and cardiac target organ damage (TOD).

Methods
A retrospective analysis was performed including 200 patients registered in the Regione Campania network (aged 62.4 ± 12, male 64%). HRV analysis was performed by 24-h holter ECG. Renal damage was assessed by estimated glomerular filtration rate (eGFR), vascular damage by carotid intima-media thickness (IMT), and cardiac damage by left ventricular mass index.

Results
Significantly lower values of the ratio of low to high frequency power (LF/HF) were found in the patients with moderate or severe eGFR (p-value 

Journal Article Type Article
Publication Date Nov 15, 2012
Journal BMC Cardiovascular Disorders
Electronic ISSN 1471-2261
Publisher Humana Press
Peer Reviewed Peer Reviewed
Volume 12
Issue Novemb
Article Number 11
Institution Citation Melillo, P., Izzo, R., De Luca, N., & Pecchia, L. (2012). Heart rate variability and target organ damage in hypertensive patients. BMC Cardiovascular Disorders, 12(Novemb), doi:10.1186/1471-2261-12-105
DOI https://doi.org/10.1186/1471-2261-12-105
Publisher URL http://www.biomedcentral.com/1471-2261/12/105
Copyright Statement Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0




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