Morphology, adipocyte size, and fatty acid analysis of dairy cattle digital cushions, and the effect of body condition score and age

Newsome, R. F.; Mostyn, A.; Wilson, J. P.; Alibhai, A.; Bollard, N.; Randall, L.; Chagunda, M. G. G.; Sturrock, C. J.; Keane, M.; Green, M.; Huxley, J. N.; Rutland, C. S.

doi:10.3168/jds.2020-19388

Anatomy, histology, development and functions of Ossa cordis: A review (2022)
Journal Article
Best, A., Egerbacher, M., Swaine, S., Pérez, W., Alibhai, A., Rutland, P., …Rutland, C. S. (2022). Anatomy, histology, development and functions of Ossa cordis: A review. Anatomia, Histologia, Embryologia, 51(6), 683-695. https://doi.org/10.1111/ahe.12861

This systematic review highlights the similarities and variations in Ossa cordis prevalence, histology and anatomical location between differing veterinary species and in humans. In addition, it also identifies associated factors such as aging and ca... Read More about Anatomy, histology, development and functions of Ossa cordis: A review.

Artificial microvesicles: new perspective on healing tendon wounds (2022)
Journal Article
Zakirova, E., Aimaletdinov, A., Mansurova, M., Titova, A., Kurilov, I., Rutland, C. S., …Rizvanov, A. (2022). Artificial microvesicles: new perspective on healing tendon wounds. Cells Tissues Organs, https://doi.org/10.1159/000526845

Tendons have a limited capacity to repair both naturally and following clinical interventions. Damaged tissue often presents with structural and functional differences, adversely affecting animal performance, mobility, health and welfare. Advances in... Read More about Artificial microvesicles: new perspective on healing tendon wounds.

Salivary Gland Adaptation to Dietary Inclusion of Hydrolysable Tannins in Boars (2022)
Journal Article
Mavri, M., Čandek-Potokar, M., Fazarinc, G., Škrlep, M., Rutland, C. S., Potočnik, B., …Kubale, V. (2022). Salivary Gland Adaptation to Dietary Inclusion of Hydrolysable Tannins in Boars. Animals, 12(17), Article 2171. https://doi.org/10.3390/ani12172171

The ingestion of hydrolysable tannins as a potential nutrient to reduce boar odor in entire males results in the significant enlargement of parotid glands (parotidomegaly). The objective of this study was to characterize the effects of different leve... Read More about Salivary Gland Adaptation to Dietary Inclusion of Hydrolysable Tannins in Boars.

Isolation, culturing and 3D bioprinting of equine myoblasts (2022)
Journal Article
Aimaletdinov, A., Abyzova, M., Kurilov, I., Yuferova, A., Rutland, C., Rizvanov, A., & Zakirova, E. (2022). Isolation, culturing and 3D bioprinting of equine myoblasts. Biological Communications, 67(3), 152-159. https://doi.org/10.21638/spbu03.2022.302

Isolating and culturing myoblasts is essential for techniques such as tissue regeneration and in vitro meat production. This research describes a protocol to isolate primary myoblasts from skeletal muscle of an adult horse. The equine primary myoblas... Read More about Isolation, culturing and 3D bioprinting of equine myoblasts.

Impact of COVID-19 on student attainment and pedagogical needs when undertaking independent scientific research (2022)
Journal Article
Jeyapalan, J. N., James, V., Gardner, D. S., Lothion-Roy, J. H., Mongan, N. P., & Rutland, C. S. (2022). Impact of COVID-19 on student attainment and pedagogical needs when undertaking independent scientific research. Anatomia, Histologia, Embryologia, https://doi.org/10.1111/ahe.12842

Research is often an essential component of completing a veterinary medicine degree, with universities worldwide aiming to teach students a variety of techniques and general research comprehension and skills. As universities worldwide navigated the C... Read More about Impact of COVID-19 on student attainment and pedagogical needs when undertaking independent scientific research.

Effects of routine treatment with nonsteroidal anti-inflammatory drugs at calving and when lame on the future probability of lameness and culling in dairy cows: A randomized controlled trial (2022)
Journal Article
Wilson, J., Green, M., Randall, L., Rutland, C., Bell, N., Hemingway-Arnold, H., …Huxley, J. (2022). Effects of routine treatment with nonsteroidal anti-inflammatory drugs at calving and when lame on the future probability of lameness and culling in dairy cows: A randomized controlled trial. Journal of Dairy Science, 105(7), 6041-6054. https://doi.org/10.3168/jds.2021-21329

Claw horn lesions (CHL) are reported as the most common cause of lameness in intensive dairy systems. Despite their prevalence, the underlying pathological mechanisms and preventive strategies for CHL remain poorly understood. Recent advances have po... Read More about Effects of routine treatment with nonsteroidal anti-inflammatory drugs at calving and when lame on the future probability of lameness and culling in dairy cows: A randomized controlled trial.

Genetic Therapy in Veterinary Medicine (2022)
Journal Article
Zakirova, E. Y., Malanyeva, A. G., Rutland, C. S., & Aimaletdinov, A. M. (2022). Genetic Therapy in Veterinary Medicine. BioNanoScience, https://doi.org/10.1007/s12668-022-00986-y

Gene therapy focuses on the genetic modification of cells, to produce a therapeutic effect or for the treatment of disease, by repairing or reconstructing defective genetic material. The development of genetic engineering and biotechnology makes it p... Read More about Genetic Therapy in Veterinary Medicine.

Viral Vector Vaccines Against ASF: Problems and Prospectives (2022)
Journal Article
Ravilov, R. K., Rizvanov, A. A., Mingaleev, D. N., Galeeva, A. G., Zakirova, E. Y., Shuralev, E. A., …Efimova, M. A. (2022). Viral Vector Vaccines Against ASF: Problems and Prospectives. Frontiers in Veterinary Science, 9, Article 830244. https://doi.org/10.3389/fvets.2022.830244

African swine fever (ASF) is a highly contagious viral disease affecting pigs, with mortality rates a primary focus as they can reach up to 100%. The widespread and colossal economic losses from ASF have impacts on the development of animal husbandry... Read More about Viral Vector Vaccines Against ASF: Problems and Prospectives.

Health care providers’ awareness on medical management of children with autism spectrum disorder: cross-sectional study in Russia (2022)
Journal Article
Mukhamedshina, Y. O., Fayzullina, R. A., Nigmatullina, I. A., Rutland, C. S., & Vasina, V. V. (2022). Health care providers’ awareness on medical management of children with autism spectrum disorder: cross-sectional study in Russia. BMC Medical Education, 22, Article 29. https://doi.org/10.1186/s12909-021-03095-8

Background: Autism spectrum disorder (ASD) is a complex developmental range of conditions that involves difficulties with social interaction and restricted/repetitive behaviors. Unfortunately, health care providers often experience difficulties in di... Read More about Health care providers’ awareness on medical management of children with autism spectrum disorder: cross-sectional study in Russia.

Discovery Of A Bone In Chimpanzee Hearts (2022)
Journal Article
Sturrock, C. J., Stanford, K., Moittie, S., Baiker, K., Redrobe, S., & Rutland, C. S. (2022). Discovery Of A Bone In Chimpanzee Hearts. Frontiers for Young Minds, 9, Article 592105. https://doi.org/10.3389/frym.2021.592105

The os cordis (heart bone) is a rare bone found only in a few animals in the world. We discovered an os cordis in some chimpanzees. The os cordis was found in males and females, and in young and old animals. It was not present in chimps with healthy... Read More about Discovery Of A Bone In Chimpanzee Hearts.

Why Do We Need Maths in Medicine? (2021)
Journal Article
Cockcroft, J., Saigar, M., Dawkins, A., & Rutland, C. S. (2021). Why Do We Need Maths in Medicine?. Frontiers for Young Minds, 9, Article 678802. https://doi.org/10.3389/frym.2021.678802

Maths is a crucial part of medicine. All the graphs, equations, statistics, and general maths we learn at school help us to understand important aspects of human and veterinary medicine, biology, and science in general. People always think that biolo... Read More about Why Do We Need Maths in Medicine?.

Comparative pathology of dog and human prostate cancer (2021)
Journal Article
Ryman-Tubb, T., Lothion-Roy, J. H., Metzler, V. M., Harris, A. E., Robinson, B. D., Rizvanov, A. A., …de Brot, S. (2022). Comparative pathology of dog and human prostate cancer. Veterinary Medicine and Science, 8(1), 110-120. https://doi.org/10.1002/vms3.642

Though relatively rare in dogs, prostate cancer (PCa) is the most common non-cutaneous cancer in men. Human and canine prostate glands share many functional, anatomical and physiological features. Due to these similarities, canine PCa has been propos... Read More about Comparative pathology of dog and human prostate cancer.

Recent Advances in Experimental Dendritic Cell Vaccines for Cancer (2021)
Journal Article
Filin, I. Y., Kitaeva, K. V., Rutland, C. S., Rizvanov, A. A., & Solovyeva, V. V. (2021). Recent Advances in Experimental Dendritic Cell Vaccines for Cancer. Frontiers in Oncology, 11, 1-7. https://doi.org/10.3389/fonc.2021.730824

The development of immunotherapeutic methods for the treatment of oncological diseases have made it possible to improve the effectiveness of standard therapies. There was no breakthrough after first using of personalized therapeutic vaccines based on... Read More about Recent Advances in Experimental Dendritic Cell Vaccines for Cancer.

Morphological investigation of canine epigastric organs and adjacent structures via computed tomography, ultrasound and anatomical prosection (2021)
Journal Article
Alsafy, M. A., Hanafy, B. G., Rutland, C. S., Karkoura, A. A., Enany, E., & El-gendy, S. A. (2022). Morphological investigation of canine epigastric organs and adjacent structures via computed tomography, ultrasound and anatomical prosection. Morphologie, 106(355), 271-286. https://doi.org/10.1016/j.morpho.2021.08.001

The canine epigastric organs, their locations and visualization of these components are essential for veterinary practice and anatomical research. Despite their importance, conflicts and discrepancies in the published material, to date, still exist,... Read More about Morphological investigation of canine epigastric organs and adjacent structures via computed tomography, ultrasound and anatomical prosection.

Immunohistochemical Characterisation of GLUT1, MMP3 and NRF2 in Osteosarcoma (2021)
Journal Article
Rutland, C. S., Cockcroft, J. M., Lothion-Roy, J., Harris, A. E., Jeyapalan, J. N., Simpson, S., …Mongan, N. P. (2021). Immunohistochemical Characterisation of GLUT1, MMP3 and NRF2 in Osteosarcoma. Frontiers in Veterinary Science, 8, Article 704598. https://doi.org/10.3389/fvets.2021.704598

Osteosarcoma (OSA) is an aggressive bone malignancy. Unlike many other malignancies, OSA outcomes have not improved in recent decades. One challenge to the development of better diagnostic and therapeutic methods for OSA has been the lack of well cha... Read More about Immunohistochemical Characterisation of GLUT1, MMP3 and NRF2 in Osteosarcoma.

A Trifecta of New Insights into Ovine Footrot for Infection Drivers, Immune Response, and Host-Pathogen Interactions (2021)
Journal Article
Blanchard, A. M., Staley, C. E., Shaw, L., Wattegedera, S. R., Baumbach, C., Michler, J. K., …Tötemeyer, S. (2021). A Trifecta of New Insights into Ovine Footrot for Infection Drivers, Immune Response, and Host-Pathogen Interactions. Infection and Immunity, 89(10), Article e00270-21. https://doi.org/10.1128/iai.00270-21

Footrot is a polymicrobial infectious disease in sheep causing severe lameness, leading to one of the industry’s largest welfare problems. The complex etiology of footrot makes in situ or in vitro investigations difficult. Computational methods offer... Read More about A Trifecta of New Insights into Ovine Footrot for Infection Drivers, Immune Response, and Host-Pathogen Interactions.

Proangiogenic Effect of 2A-Peptide Based Multicistronic Recombinant Constructs Encoding VEGF and FGF2 Growth Factors (2021)
Journal Article
Gatina, D. Z., Garanina, E. E., Zhuravleva, M. N., Synbulatova, G. E., Mullakhmetova, A. F., Solovyeva, V. V., …Salafutdinov, I. I. (2021). Proangiogenic Effect of 2A-Peptide Based Multicistronic Recombinant Constructs Encoding VEGF and FGF2 Growth Factors. International Journal of Molecular Sciences, 22(11), Article 5922. https://doi.org/10.3390/ijms22115922

Coronary artery disease remains one of the primary healthcare problems due to the high cost of treatment, increased number of patients, poor clinical outcomes, and lack of effective therapy. Though pharmacological and surgical treatments positively a... Read More about Proangiogenic Effect of 2A-Peptide Based Multicistronic Recombinant Constructs Encoding VEGF and FGF2 Growth Factors.

A history of lameness and low body condition score is associated with reduced digital cushion volume, measured by magnetic resonance imaging, in dairy cattle (2021)
Journal Article
Wilson, J., Randall, L., Green, M., Rutland, C., Bradley, C., Ferguson, H., …Huxley, J. (2021). A history of lameness and low body condition score is associated with reduced digital cushion volume, measured by magnetic resonance imaging, in dairy cattle. Journal of Dairy Science, https://doi.org/10.3168/jds.2020-19843

Morphology, adipocyte size, and fatty acid analysis of dairy cattle digital cushions, and the effect of body condition score and age (2021)
Journal Article
Newsome, R. F., Mostyn, A., Wilson, J. P., Alibhai, A., Bollard, N., Randall, L., …Rutland, C. S. (2021). Morphology, adipocyte size, and fatty acid analysis of dairy cattle digital cushions, and the effect of body condition score and age. Journal of Dairy Science, 104(5), https://doi.org/10.3168/jds.2020-19388

The digital cushion is an essential part of maintaining a healthy foot, working to dissipate foot strike and body weight forces and lameness from claw horn disruption lesions. Despite the importance of the digital cushion, little is known about the b... Read More about Morphology, adipocyte size, and fatty acid analysis of dairy cattle digital cushions, and the effect of body condition score and age.

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