Ivan Y. Filin
Recent Advances in Experimental Dendritic Cell Vaccines for Cancer
Filin, Ivan Y.; Kitaeva, Kristina V.; Rutland, Catrin S.; Rizvanov, Albert A.; Solovyeva, Valeriya V.
Authors
Kristina V. Kitaeva
Professor CATRIN RUTLAND CATRIN.RUTLAND@NOTTINGHAM.AC.UK
PROFESSOR OF MOLECULAR MEDICINE
Albert A. Rizvanov
Valeriya V. Solovyeva
Abstract
The development of immunotherapeutic methods for the treatment of oncological diseases have made it possible to improve the effectiveness of standard therapies. There was no breakthrough after first using of personalized therapeutic vaccines based on dendritic cells in clinical practice. A deeper study of the biology of dendritic cells, as well as the use of new approaches and agents for antigenic work, have made it possible to expand the field of application of dendritic cell (DC) vaccines and improve the indicators of cancer patients. In addition, the low toxicity of DC vaccines in clinical trials makes it possible to use promising predictions of their applicability in wider clinical practice. This review examines new approaches and recent advances of the DC vaccine in clinical trials.
Citation
Filin, I. Y., Kitaeva, K. V., Rutland, C. S., Rizvanov, A. A., & Solovyeva, V. V. (2021). Recent Advances in Experimental Dendritic Cell Vaccines for Cancer. Frontiers in Oncology, 11, 1-7. https://doi.org/10.3389/fonc.2021.730824
Journal Article Type | Review |
---|---|
Acceptance Date | Sep 7, 2021 |
Online Publication Date | Sep 23, 2021 |
Publication Date | Sep 23, 2021 |
Deposit Date | Oct 5, 2021 |
Publicly Available Date | Oct 5, 2021 |
Journal | Frontiers in Oncology |
Electronic ISSN | 2234-943X |
Publisher | Frontiers Media |
Peer Reviewed | Peer Reviewed |
Volume | 11 |
Article Number | 730824 |
Pages | 1-7 |
DOI | https://doi.org/10.3389/fonc.2021.730824 |
Keywords | Cancer Research; Oncology |
Public URL | https://nottingham-repository.worktribe.com/output/6391566 |
Publisher URL | https://www.frontiersin.org/articles/10.3389/fonc.2021.730824/full |
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Recent Advances in Experimental Dendritic Cell Vaccines for Cancer
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Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/
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