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Recent Advances in Experimental Dendritic Cell Vaccines for Cancer

Filin, Ivan Y.; Kitaeva, Kristina V.; Rutland, Catrin S.; Rizvanov, Albert A.; Solovyeva, Valeriya V.

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Authors

Ivan Y. Filin

Kristina V. Kitaeva

Albert A. Rizvanov

Valeriya V. Solovyeva



Abstract

The development of immunotherapeutic methods for the treatment of oncological diseases have made it possible to improve the effectiveness of standard therapies. There was no breakthrough after first using of personalized therapeutic vaccines based on dendritic cells in clinical practice. A deeper study of the biology of dendritic cells, as well as the use of new approaches and agents for antigenic work, have made it possible to expand the field of application of dendritic cell (DC) vaccines and improve the indicators of cancer patients. In addition, the low toxicity of DC vaccines in clinical trials makes it possible to use promising predictions of their applicability in wider clinical practice. This review examines new approaches and recent advances of the DC vaccine in clinical trials.

Citation

Filin, I. Y., Kitaeva, K. V., Rutland, C. S., Rizvanov, A. A., & Solovyeva, V. V. (2021). Recent Advances in Experimental Dendritic Cell Vaccines for Cancer. Frontiers in Oncology, 11, 1-7. https://doi.org/10.3389/fonc.2021.730824

Journal Article Type Review
Acceptance Date Sep 7, 2021
Online Publication Date Sep 23, 2021
Publication Date Sep 23, 2021
Deposit Date Oct 5, 2021
Publicly Available Date Oct 5, 2021
Journal Frontiers in Oncology
Electronic ISSN 2234-943X
Publisher Frontiers Media
Peer Reviewed Peer Reviewed
Volume 11
Article Number 730824
Pages 1-7
DOI https://doi.org/10.3389/fonc.2021.730824
Keywords Cancer Research; Oncology
Public URL https://nottingham-repository.worktribe.com/output/6391566
Publisher URL https://www.frontiersin.org/articles/10.3389/fonc.2021.730824/full

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