All Outputs (26)

Investigation of Exhaust Particles on Different TEM Grids: a Comparison between Graphene Oxide and Silicon Nitride Grids (2023)
Journal Article

Two different TEM (Transmission Electron Microscopy) grids - graphene oxide (GO) and silicon nitride (SiN) - were used to capture the particulates emitted with the exhaust of a modern 1.0 L GDI (Gasoline Direct Injection) engine. One speed-load condi... Read More about Investigation of Exhaust Particles on Different TEM Grids: a Comparison between Graphene Oxide and Silicon Nitride Grids.

The Modular μSiM: a Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro (2022)
Journal Article

Advanced in vitro tissue chip models can reduce and replace animal experimentation and may eventually support "on-chip" clinical trials. To realize this potential, however, tissue chip platforms must be both mass-produced and reconfigurable to allow... Read More about The Modular μSiM: a Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro.

Non-invasive hydrodynamic imaging in plant roots at cellular resolution (2021)
Journal Article

A key impediment to studying water-related mechanisms in plants is the inability to non-invasively image water fluxes in cells at high temporal and spatial resolution. Here, we report that Raman microspectroscopy, complemented by hydrodynamic modelli... Read More about Non-invasive hydrodynamic imaging in plant roots at cellular resolution.

Picosecond ultrasonics for elasticity-based imaging and characterization of biological cells (2020)
Journal Article

© 2020 Author(s). Characterization of the elasticity of biological cells is growing as a new way to gain insight into cell biology. Cell mechanics are related to most aspects of cellular behavior, and applications in research and medicine are broad.... Read More about Picosecond ultrasonics for elasticity-based imaging and characterization of biological cells.

Effects of Toxoplasma gondii infection on the function and integrity of human cerebrovascular endothelial cells and the influence of Verapamil treatment in vitro (2020)
Journal Article

Toxoplasma gondii can cause parasitic encephalitis, a life-threatening infection that predominately occurs in immunocompromised individuals. T. gondii has the ability to invade the brain, but the mechanisms by which this parasite crosses the blood–br... Read More about Effects of Toxoplasma gondii infection on the function and integrity of human cerebrovascular endothelial cells and the influence of Verapamil treatment in vitro.

Surface plasmon resonance imaging of excitable cells (2019)
Journal Article

Surface plasmons (SPs) are surface charge density oscillations occuring at a metal/dieletric interface and are highly sensitive to refractive index variations adjacent to the surface. This sensitivity has been exploited successfully for chemical and... Read More about Surface plasmon resonance imaging of excitable cells.

TEM tomography of pores with application to computational nanoscale flows in nanoporous silicon nitride (NPN) (2018)
Journal Article

Silicon nanomembrane technologies (NPN, pnc-Si, and others) have been used commercially as electron microscopy (EM) substrates, and as filters with nanometer-resolution size cut-offs. Combined with EM, these materials provide a platform for catching... Read More about TEM tomography of pores with application to computational nanoscale flows in nanoporous silicon nitride (NPN).

Non destructive evaluation of biological cells (2018)
Journal Article

© 2019 Author(s). Regenerative medicine promises to be the next revolution in health care. This technology, which will be the first systematic manufacturing of biological parts for human consumption, requires non destructive evaluatioin (NDE) thechni... Read More about Non destructive evaluation of biological cells.

Rapid one-step biotinylation of biological and non-biological surfaces (2018)
Journal Article

We describe a rapid one-step method to biotinylate virtually any biological or non-biological surface. Contacting a solution of biotin-spacer-lipid constructs with a surface will form a coating within seconds on non-biological surfaces or within minu... Read More about Rapid one-step biotinylation of biological and non-biological surfaces.

Dynamic functional contribution of the water channel AQP5 to the water permeability of peripheral lens fiber cells (2018)
Journal Article

Although the functionality of the lens water channels aquaporin 1 (AQP1; epithelium) and AQP0 (fiber cells) is well established, less is known about the role of AQP5 in the lens. Since in other tissues AQP5 functions as a regulated water channel with... Read More about Dynamic functional contribution of the water channel AQP5 to the water permeability of peripheral lens fiber cells.

Sensitive detection of voltage transients using differential intensity surface plasmon resonance system (2017)
Journal Article

This paper describes theoretical and experimental study of the fundamentals of using surface plasmon resonance (SPR) for label-free detection of voltage. Plasmonic voltage sensing relies on the capacitive properties of metal-electrolyte interface tha... Read More about Sensitive detection of voltage transients using differential intensity surface plasmon resonance system.

Cell imaging by phonon microscopy: sub-optical wavelength ultrasound for non-invasive imaging (2017)
Journal Article

The mechanical properties of cells play an important role in cell function and behavior. This paper presents recent developments that have enabled the use of laser-generated phonons (ultrasound) with sub-optical wavelengths to look inside living cell... Read More about Cell imaging by phonon microscopy: sub-optical wavelength ultrasound for non-invasive imaging.

High resolution 3D imaging of living cells with sub-optical wavelength phonons (2016)
Journal Article

Label-free imaging of living cells below the optical diffraction limit poses great challenges for optical microscopy. Biologically relevant structural information remains below the Rayleigh limit and beyond the reach of conventional microscopes. Supe... Read More about High resolution 3D imaging of living cells with sub-optical wavelength phonons.

Responsivity of the differential-intensity surface plasmon resonance instrument (2016)
Journal Article

Surface plasmon resonance is used for the sensitive measurement of minute concentrations of bio-analytes and probing of electrochemical processes. Typical refractive index sensitivity, for the intensity approach, is around 10−6 refractive index units... Read More about Responsivity of the differential-intensity surface plasmon resonance instrument.

Thin-film transducers for the detection and imaging of Brillouin oscillations in transmission on cultured cells (2015)
Journal Article

Mechanical imaging and characterisation of biological cells has been a subject of interest for the last twenty years. Ultrasonic imaging based on the scanning acoustic microscope (SAM) and mechanical probing have been extensively reported. Large acou... Read More about Thin-film transducers for the detection and imaging of Brillouin oscillations in transmission on cultured cells.

Thin-film optoacoustic transducers for the subcellular Brillouin oscillation imaging of individual biological cells (2015)
Journal Article

Mechanical characterisation and imaging of biological tissue has piqued interest in the applicability to cell and tissue biology. One method, based on detection of Brillouin oscillations, has already lead to demonstrations on biological cells using u... Read More about Thin-film optoacoustic transducers for the subcellular Brillouin oscillation imaging of individual biological cells.

Optically excited nanoscale ultrasonic transducers (2015)
Journal Article

© 2015 Acoustical Society of America. In order to work at higher ultrasonic frequencies, for instance, to increase the resolution, it is necessary to fabricate smaller and higher frequency transducers. This paper presents an ultrasonic transducer cap... Read More about Optically excited nanoscale ultrasonic transducers.

Sub-100 nm resolution microscopy based on proximity projection grating scheme (2015)
Journal Article

Structured illumination microscopy (SIM) has been widely used in life science imaging applications. The maximum resolution improvement of SIM, compared to conventional bright field system is a factor of 2. Here we present an approach to structured il... Read More about Sub-100 nm resolution microscopy based on proximity projection grating scheme.

Condenser-free contrast methods for transmitted-light microscopy (2014)
Journal Article

Phase contrast microscopy allows the study of highly transparent yet detail-rich specimens by producing intensity contrast from phase objects within the sample. Presented here is a generalized phase contrast illumination schema in which condenser opt... Read More about Condenser-free contrast methods for transmitted-light microscopy.

Sound of nano (2013)
Journal Article

Ultrasound is widely used for imaging, measurement and diagnostics in the MHz region and is perhaps most familiar as a medical or non-destructive imaging or measurement tool. In the MHz frequency range the wavelength is typically measured in microns... Read More about Sound of nano.