Non destructive evaluation of biological cells

P�rez-Cota, Fernando; Smith, Richard J.; Moradi, Emilia; Webb, Kevin F.; Clark, Matt

Abstract

© 2019 Author(s). Regenerative medicine promises to be the next revolution in health care. This technology, which will be the first systematic manufacturing of biological parts for human consumption, requires non destructive evaluatioin (NDE) thechniques for the inspection and quality assurance of products such as tissue and organs. Ultrasound is the technology of choice due to its low invasiveness however state of the art is limited in resolution and not able to inspect single cells. In this paper we present a novel NDE technique applicable for single cells that uses sound, offers contrast provided by mechanical properties, does not require toxic chemical labels and can achieve optical or higher resolution. This will be required for tissue manufacturing as the current technologies used for research on the life-sciences heavily depends on toxic chemicals and radiation. This will stablish ultrasound as a single platform for the inspection of biological products at all scales.

Citation

Pérez-Cota, F., Smith, R. J., Moradi, E., Webb, K. F., & Clark, M. (2019). Non destructive evaluation of biological cells. AIP Conference Proceedings, 2102, https://doi.org/10.1063/1.5099737

• Journal Article Type: Conference Paper
• Acceptance Date: May 8, 2019
• Online Publication Date: May 8, 2018
• Publication Date: May 8, 2019
• Deposit Date: Feb 1, 2022
• Publicly Available Date: Feb 2, 2022
• Journal: AIP Conference Proceedings
• Print ISSN: 0094-243X
• Electronic ISSN: 1551-7616
• Publisher: AIP Publishing
• Peer Reviewed: Peer Reviewed
• Volume: 2102
• DOI: https://doi.org/10.1063/1.5099737
• Public URL: https://nottingham-repository.worktribe.com/output/3156688
• Publisher URL: https://aip.scitation.org/doi/pdf/10.1063/1.5099737
• Additional Information: This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Fernando Pérez-Cota, Richard J. Smith, Emilia Moradi, Kevin F. Webb, and Matt Clark , "Non destructive evaluation of biological cells", AIP Conference Proceedings 2102, 020033 (2019) and may be found at https://aip.scitation.org/doi/abs/10.1063/1.5099737