All Outputs (40)

Simultaneous whole-head electrophysiological recordings using EEG and OPM-MEG (2024)
Journal Article

Electroencephalography (EEG) and magnetoencephalography (MEG) non-invasively measure human brain electrophysiology. They differ in nature; MEG offers better performance whilst EEG (a wearable platform) is more practical. They are also complementary,... Read More about Simultaneous whole-head electrophysiological recordings using EEG and OPM-MEG.

Neurovascular coupling methods in healthy individuals using transcranial Doppler ultrasonography: A systematic review and consensus agreement (2024)
Journal Article

Post‐task responses following working memory and movement are driven by transient spectral bursts with similar characteristics (2024)
Journal Article

The post-movement beta rebound has been studied extensively using magnetoencephalography (MEG) and is reliably modulated by various task parameters as well as illness. Our recent study showed that rebounds, which we generalise as “post-task responses... Read More about Post‐task responses following working memory and movement are driven by transient spectral bursts with similar characteristics.

Measurement of Frontal Midline Theta Oscillations using OPM-MEG (2023)
Journal Article

Optically pumped magnetometers (OPMs) are an emerging lightweight and compact sensor that can measure magnetic fields generated by the human brain. OPMs enable construction of wearable magnetoencephalography (MEG) systems, which offer advantages over... Read More about Measurement of Frontal Midline Theta Oscillations using OPM-MEG.

Beyond the Beta Rebound: Post-Task Responses in Oscillatory Activity follow Cessation of Working Memory Processes (2022)
Journal Article

Post-task responses (PTRs) are transitionary responses occurring for several seconds between the end of a stimulus/task and a period of rest. The most well-studied of these are beta band (13 – 30 Hz) PTRs in motor networks following movement, often c... Read More about Beyond the Beta Rebound: Post-Task Responses in Oscillatory Activity follow Cessation of Working Memory Processes.

Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study (2022)
Journal Article

Epilepsy is a highly heterogeneous neurological disorder with variable etiology, manifestation, and response to treatment. It is imperative that new models of epileptiform brain activity account for this variability, to identify individual needs and... Read More about Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study.

Across the adult lifespan the ipsilateral sensorimotor cortex negative BOLD response exhibits decreases in magnitude and spatial extent suggesting declining inhibitory control (2022)
Journal Article

Ipsilateral sensorimotor (iSM1) cortex negative BOLD responses (NBR) are observed to unilateral tasks and are thought to reflect a functionally relevant component of sensorimotor inhibition. Evidence suggests that sensorimotor inhibitory mechanisms d... Read More about Across the adult lifespan the ipsilateral sensorimotor cortex negative BOLD response exhibits decreases in magnitude and spatial extent suggesting declining inhibitory control.

Imaging Cerebral Blood Flow for Brain Health Measurement (2021)
Book Chapter

Cerebral blood flow (CBF) measures are used in clinical settings to diagnose conditions (e.g., vasospasms, sickle cell disease, stroke, dementia, confirmation of brain death), as well as in research, emerging as potential early biomarkers of declinin... Read More about Imaging Cerebral Blood Flow for Brain Health Measurement.

Beta-frequency electrophysiological bursts: BOLD correlates and relationships with psychotic illness (2021)
Journal Article

Measuring resting cerebral haemodynamics using MRI arterial spin labelling and transcranial Doppler ultrasound: comparison in younger and older adults (2021)
Journal Article

Introduction: Resting cerebral blood flow (CBF) and perfusion measures have been used to determine brain health. Studies showing variation in resting CBF with age and fitness level using different imaging approaches have produced mixed findings. We a... Read More about Measuring resting cerebral haemodynamics using MRI arterial spin labelling and transcranial Doppler ultrasound: comparison in younger and older adults.

Contrasting Measures of Cerebrovascular Reactivity Between MRI and Doppler: A Cross-Sectional Study of Younger and Older Healthy Individuals (2021)
Journal Article

Cerebrovascular reactivity (CVR) is used as an outcome measure of brain health. Traditionally, lower CVR is associated with ageing, poor fitness and brain-related conditions (e.g. stroke, dementia). Indeed, CVR is suggested as a biomarker for disease... Read More about Contrasting Measures of Cerebrovascular Reactivity Between MRI and Doppler: A Cross-Sectional Study of Younger and Older Healthy Individuals.

Regional Brain Correlates of Beta Bursts in Health and Psychosis: A Concurrent Electroencephalography and Functional Magnetic Resonance Imaging Study (2020)
Journal Article

Background: There is emerging evidence for abnormal beta oscillations in psychosis. Beta oscillations are likely to play a key role in the coordination of sensorimotor information that is crucial to healthy mental function. Growing evidence suggests... Read More about Regional Brain Correlates of Beta Bursts in Health and Psychosis: A Concurrent Electroencephalography and Functional Magnetic Resonance Imaging Study.

The CO2?stimulus duration and steady?state time?point used for data extraction alters the cerebrovascular reactivity outcome measure (2020)
Journal Article

Cerebrovascular reactivity to carbon dioxide (CVR) is a common functional test to assess brain vascular health, though conflicting age and fitness effects have been reported. Studies have used different CO2 -stimulus durations to induce CVR and extra... Read More about The CO2?stimulus duration and steady?state time?point used for data extraction alters the cerebrovascular reactivity outcome measure.

The role of transient spectral ‘bursts’ in functional connectivity: A magnetoencephalography study (2020)
Journal Article

Alpha/beta power decreases track the fidelity of stimulus-specific information (2019)
Journal Article

© 2019, Griffiths et al. Massed synchronised neuronal firing is detrimental to information processing. When networks of task-irrelevant neurons fire in unison, they mask the signal generated by task-critical neurons. On a macroscopic level, such sync... Read More about Alpha/beta power decreases track the fidelity of stimulus-specific information.

Post-stimulus beta responses are modulated by task duration (2019)
Journal Article

Modulation of beta-band neural oscillations during and following movement is a robust marker of brain function. In particular, the post-movement beta rebound (PMBR), which occurs on movement cessation, has been related to inhibition and connectivity... Read More about Post-stimulus beta responses are modulated by task duration.

Wearable neuroimaging: Combining and contrasting magnetoencephalography and electroencephalography (2019)
Journal Article

Two spatially distinct posterior alpha sources fulfill different functional roles in attention (2019)
Journal Article

Directing attention helps extracting relevant information and suppressing distracters. Alpha brain oscillations (8-12Hz) are crucial for this process, with power decreases facilitating processing of important information and power increases inhibitin... Read More about Two spatially distinct posterior alpha sources fulfill different functional roles in attention.

The relationship between negative BOLD responses and ERS and ERD of alpha/beta oscillations in visual and motor cortex (2019)
Journal Article

Previous work has investigated the electrophysiological origins of the intra-modal (within the stimulated sensory cortex) negative BOLD fMRI response (NBR, decrease from baseline) but little attention has been paid to the origin of cross-modal NBRs,... Read More about The relationship between negative BOLD responses and ERS and ERD of alpha/beta oscillations in visual and motor cortex.

Addressing challenges of high spatial resolution UHF fMRI for group analysis of higher?order cognitive tasks: An inter?sensory task directing attention between visual and somatosensory domains (2018)
Journal Article

Functional MRI at ultra-high field (UHF, ?7T) provides significant increases in BOLD contrast-to-noise ratio (CNR) compared with conventional field strength (3T), and has been exploited for reduced field-of-view, high spatial resolution mapping of pr... Read More about Addressing challenges of high spatial resolution UHF fMRI for group analysis of higher?order cognitive tasks: An inter?sensory task directing attention between visual and somatosensory domains.