All Outputs (58)

Controlling equine influenza: Traditional to next generation serological assays (2016)
Journal Article

Serological assays provide an indirect route for the recognition of infectious agents via the detection of antibodies against the infectious agent of interest within serum. Serological assays for equine influenza A virus can be applied for different... Read More about Controlling equine influenza: Traditional to next generation serological assays.

Technical considerations for the generation of novel pseudotyped viruses (2016)
Journal Article

A pseudotyped virus (PV) is a virus particle with an envelope protein originating from a different virus. The ability to dictate which envelope proteins are expressed on the surface has made pseudotyping an important tool for basic virological studie... Read More about Technical considerations for the generation of novel pseudotyped viruses.

Modulation of potassium channels inhibits bunyavirus infection (2015)
Journal Article

Bunyaviruses are considered to be emerging pathogens facilitated by the segmented nature of their genome that allows reassortment between different species to generate novel viruses with altered pathogenicity. Bunyaviruses are transmitted via a diver... Read More about Modulation of potassium channels inhibits bunyavirus infection.

Diversity of group A rotavirus on a UK pig farm (2015)
Journal Article

Group A rotaviruses (GARV) are a significant cause of enteritis in young pigs. The aim of this study was to extend our understanding of the molecular epidemiology of porcine GARV in the UK by investigating the genetic diversity of GARV on a conventio... Read More about Diversity of group A rotavirus on a UK pig farm.

Seroprevalence of Schmallenberg virus in the United Kingdom and the Republic of Ireland: 2011-2013 (2015)
Journal Article

© 2015 Elsevier B.V. Since its identification in late 2011, Schmallenberg virus (SBV) spread rapidly across Europe. Using archived samples from domestic ruminants collected between October 2011 and June 2013, the seroprevalence in the United Kingdom... Read More about Seroprevalence of Schmallenberg virus in the United Kingdom and the Republic of Ireland: 2011-2013.

Identification of morphological differences between avian influenza A viruses grown in chicken and duck cells (2015)
Journal Article

Although wild ducks are considered to be the major reservoirs for most influenza A virus subtypes, they are typically resistant to the effects of the infection. In contrast, certain influenza viruses may be highly pathogenic in other avian hosts such... Read More about Identification of morphological differences between avian influenza A viruses grown in chicken and duck cells.

Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows (2015)
Journal Article

© Daly et al.; licensee BioMed Central. Background: Schmallenberg virus (SBV) is a recently emerged virus of ruminants in Europe. Enzyme-linked immunosorbent assays (ELISA) are commonly used to detect SBV-specific antibodies in bulk tank milk samples... Read More about Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows.

High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza A virus resistance (2014)
Journal Article

Respiratory epithelial cells play a key role in influenza A virus (IAV) pathogenesis and host innate response. Transformed human respiratory cell lines are widely used in the study of IAV?host interactions due to their relative convenience, and inher... Read More about High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza A virus resistance.

Pseudotypes: your flexible friends (2014)
Journal Article

Pseudotype viruses: applications and troubleshooting' (EuroSciCon 2013), a 1-day conference held at Cineworld: The O2 (London, UK) on 2 October 2013, focused on the technique of pseudotyping enveloped viruses (for a review of the technique, see [1]).... Read More about Pseudotypes: your flexible friends.

Development of a surveillance scheme for equine influenza in the UK and characterisation of viruses isolated in Europe, Dubai and the USA from 2010-2012 (2014)
Journal Article

Equine influenza viruses are a major cause of respiratory disease in horses worldwide and undergo antigenic drift. Several outbreaks of equine influenza occurred worldwide during 2010-2012, including in vaccinated animals, highlighting the importance... Read More about Development of a surveillance scheme for equine influenza in the UK and characterisation of viruses isolated in Europe, Dubai and the USA from 2010-2012.

Potential of a sequence-based antigenic distance measure to indicate equine influenza vaccine strain efficacy (2013)
Journal Article

The calculation of pepitope values, a sequence-based measure of antigenic distance between strains, was developed for human influenza. The potential to apply the pepitope value to equine influenza vaccine strain selection was assessed. There was a ne... Read More about Potential of a sequence-based antigenic distance measure to indicate equine influenza vaccine strain efficacy.

The genetics of virus particle shape in equine influenza A virus (2013)
Journal Article

Background Many human strains of influenza A virus produce highly pleomorphic virus particles that at the extremes can be approximated as either spheres of around 100 nm diameter or filaments of similar cross-section but elongated to lengths of many... Read More about The genetics of virus particle shape in equine influenza A virus.

What can mathematical models bring to the control of equine influenza? (2013)
Journal Article

Mathematical modelling of infectious disease is increasingly regarded as an important tool in the development of disease prevention and control measures. This article brings together key findings from various modelling studies conducted over the past... Read More about What can mathematical models bring to the control of equine influenza?.

Current progress with serological assays for exotic emerging / re-emerging viruses (2013)
Journal Article

Recent decades have witnessed an unprecedented rise in the outbreak occurrence of infectious and primarily zoonotic viruses. Contributing factors to this phenomenon include heightened global connectivity via air travel and international trade links,... Read More about Current progress with serological assays for exotic emerging / re-emerging viruses.

Evolution of equine influenza virus in vaccinated horses (2013)
Journal Article

Influenza A viruses are characterized by their ability to evade host immunity, even in vaccinated individuals. To determine how prior immunity shapes viral diversity in vivo, we studied the intra- and interhost evolution of equine influenza virus in... Read More about Evolution of equine influenza virus in vaccinated horses.

The challenge of Schmallenberg virus emergence in Europe (2012)
Journal Article

The large-scale outbreak of disease across Northern Europe caused by a new orthobunyavirus known as Schmallenberg virus has caused considerable disruption to lambing and calving. Although advances in technology and collaboration between veterinary... Read More about The challenge of Schmallenberg virus emergence in Europe.

Perceptions and Experiences of the University of Nottingham Pilot Asymptomatic Testing Service: A Mixed-Methods Study
Working Paper

We aimed to explore student and staff perceptions and experiences of a pilot COVID-19 asymptomatic testing service (P-ATS) in a UK university campus setting. This was a mixed-method study comprised of an online survey, and thematic analysis of qualit... Read More about Perceptions and Experiences of the University of Nottingham Pilot Asymptomatic Testing Service: A Mixed-Methods Study.

Troubleshooting methods for the generation of novel pseudotyped viruses
Journal Article

A pseudotyped virus (PV) is a virus particle with an envelope protein originating from a different virus. The ability to dictate which envelope proteins are expressed on the surface has made pseudotyping an important tool for basic virological studie... Read More about Troubleshooting methods for the generation of novel pseudotyped viruses.