All Outputs (90)

Skeleton Growth in Guinea Pigs and Humans (2021)
Journal Article

Every animal has a skeleton made up of many different bones. Bones are vital. Without bones we would not be able to move, protect our internal organs, store important minerals, or even make some cell types! When we are young, in addition to growing,... Read More about Skeleton Growth in Guinea Pigs and Humans.

The treatment of articular cartilage injuries with mesenchymal stem cells in different animal species (2021)
Journal Article

Current Trends in Cancer Immunotherapy (2020)
Journal Article

The search for an effective drug to treat oncological diseases, which have become the main scourge of mankind, has generated a lot of methods for studying this affliction. It has also become a serious challenge for scientists and clinicians who have... Read More about Current Trends in Cancer Immunotherapy.

The Importance of Anatomy (2020)
Journal Article

Anatomy is the knowledge about the structure of the bodies of animals and people. This includes information about blood vessels, organs, the skeleton, and nerves. But have you ever wondered where the anatomical information in science books and websit... Read More about The Importance of Anatomy.

Methods for studying endocytotic pathways of herpesvirus encoded g protein-coupled receptors (2020)
Journal Article

Endocytosis is a fundamental process involved in trafficking of various extracellular and transmembrane molecules from the cell surface to its interior. This enables cells to communicate and respond to external environments, maintain cellular homeost... Read More about Methods for studying endocytotic pathways of herpesvirus encoded g protein-coupled receptors.

Extracellular Vesicles: New Perspectives of Regenerative and Reproductive Veterinary Medicine (2020)
Journal Article

Extracellular vesicles are released by all cell types including stem cells. Stem cell-released extracellular vesicles have therapeutic effects similar to those of their parent cells and have regenerative effects in tissues. They also have an immunomo... Read More about Extracellular Vesicles: New Perspectives of Regenerative and Reproductive Veterinary Medicine.

Critical Impact of Different Conserved Endoplasmic Retention Motifs and Dopamine Receptor Interacting Proteins (DRIPs) on Intracellular Localization and Trafficking of the D2 Dopamine Receptor (D2-R) Isoforms (2020)
Journal Article

The type 2 dopamine receptor D2 (D2-R), member of the G protein-coupled receptor (GPCR) superfamily, exists in two isoforms, short (D2S-R) and long (D2L-R). They differ by an additional 29 amino acids (AA) in the third cytoplasmic loop (ICL3) of the... Read More about Critical Impact of Different Conserved Endoplasmic Retention Motifs and Dopamine Receptor Interacting Proteins (DRIPs) on Intracellular Localization and Trafficking of the D2 Dopamine Receptor (D2-R) Isoforms.

Promising Applications of Tumor Spheroids and Organoids for Personalized Medicine (2020)
Journal Article

One of the promising directions in personalized medicine is the use of three-dimensional (3D) tumor models such as spheroids and organoids. Spheroids and organoids are three-dimensional cultures of tumor cells that can be obtained from patient tissue... Read More about Promising Applications of Tumor Spheroids and Organoids for Personalized Medicine.

Molecular characterisation of canine osteosarcoma in high risk breeds (2020)
Journal Article

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Dogs develop osteosarcoma (OSA) and the disease process closely resembles that of human OSA. OSA has a poor prognosis in both species and disease-free intervals and cure rates have not improve... Read More about Molecular characterisation of canine osteosarcoma in high risk breeds.

Application of gene therapy in the treatment of superficial digital flexor tendon injury in horses (2020)
Journal Article

Can Toothache Cause Heartbreak? (2020)
Journal Article

Poor mouth care and heart disease are two major health concerns worldwide. Both conditions occur in humans and in many mammals, including our pets. “Periodontal” is the word used to refer to structures surrounding the teeth, including the gums and bo... Read More about Can Toothache Cause Heartbreak?.

Discovery of os cordis in the cardiac skeleton of chimpanzees (Pan troglodytes) (2020)
Journal Article

© 2020, The Author(s). Cardiovascular diseases, especially idiopathic myocardial fibrosis, is one of the most significant causes of morbidity and mortality in captive great apes. This study compared the structure and morphology of 16 hearts from chim... Read More about Discovery of os cordis in the cardiac skeleton of chimpanzees (Pan troglodytes).

Mouse Tumor Models for Advanced Cancer Immunotherapy (2020)
Journal Article

Recent advances in the development of new methods of cancer immunotherapy require the production of complex cancer animal models that reliably reflect the complexity of the tumor and its microenvironment. Mice are good animals to create tumor models... Read More about Mouse Tumor Models for Advanced Cancer Immunotherapy.

Epidemiology and risk factors of osteosarcoma (2020)
Journal Article

Osteosarcoma is a rare tumor diagnosed at any age; however younger age is a common risk factor. In addition, multiple factors are believed to contribute to higher rates of osteosarcoma, particularly race and gender. Although diagnosed worldwide, oste... Read More about Epidemiology and risk factors of osteosarcoma.

Cell Culture Based in vitro Test Systems for Anticancer Drug Screening (2020)
Journal Article

The development of new high-tech systems for screening anticancer drugs is one of the main problems of preclinical screening. Poor correlation between preclinical in vitro and in vivo data with clinical trials remains a major concern. The choice of t... Read More about Cell Culture Based in vitro Test Systems for Anticancer Drug Screening.

Blood Vessels Under the Microscope (2020)
Journal Article

This paper looks at blood vessels. All humans and animals have blood vessels, including your pet rabbit or dog, a whale or a giraffe! We need blood vessels to stay alive. This paper answers many questions, including what blood vessels are used for an... Read More about Blood Vessels Under the Microscope.

Morphological and imaging evaluation of the metacarpophalangeal and metatarsophalangeal joints in healthy and lame donkeys (2019)
Journal Article

The donkey is of socio-economic value yet imaging techniques in both healthy and abnormal limbs are a limiting factor in research and medicine. The objective was to determine anatomical features of both healthy and clinically abnormal donkey metacarp... Read More about Morphological and imaging evaluation of the metacarpophalangeal and metatarsophalangeal joints in healthy and lame donkeys.

Production and Application of Multicistronic Constructs for Various Human Disease Therapies (2019)
Journal Article

The development of multicistronic vectors has opened up new opportunities to address the fundamental issues of molecular and cellular biology related to the need for the simultaneous delivery and joint expression of several genes. To date, the exampl... Read More about Production and Application of Multicistronic Constructs for Various Human Disease Therapies.

Mechanistic investigations into the encapsulation and release of small molecules and proteins from a supramolecular nucleoside gel in vitro and in vivo (2019)
Journal Article

Supramolecular gels have recently emerged as promising biomaterials for the delivery of a wide range of bioactive molecules, from small hydrophobic drugs to large biomolecules such as proteins. Although it has been demonstrated that each encapsulated... Read More about Mechanistic investigations into the encapsulation and release of small molecules and proteins from a supramolecular nucleoside gel in vitro and in vivo.

Potential therapeutic application of mesenchymal stem cells in ophthalmology (2019)
Journal Article

At present a wide variety of methods have been proposed to treat eye disorders, drug therapies are most commonly used. It should be noted that effective treatment modalities especially for degeneration of the retina and optic nerve are lacking. In th... Read More about Potential therapeutic application of mesenchymal stem cells in ophthalmology.