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Professor STEVE MORGAN's Outputs (72)

Carboxyl-fentanyl detection using optical fibre grating-based sensors functionalised with molecularly imprinted nanoparticles (2021)
Journal Article
Liu, L. L., Grillo, F., Canfarotta, F., Whitcombe, M., Morgan, S. P., Piletsky, S., Correia, R., He, C. Y., Norris, A., & Korposh, S. (2021). Carboxyl-fentanyl detection using optical fibre grating-based sensors functionalised with molecularly imprinted nanoparticles. Biosensors and Bioelectronics, 177, Article 113002. https://doi.org/10.1016/j.bios.2021.113002

Butyrylfentanyl is a new designer drug reported with growing use and related deaths. Routine toxicological analyses of this novel synthetic opioid drug have not been established yet. This work reports a fibre optic sensor that measures carboxyl-fenta... Read More about Carboxyl-fentanyl detection using optical fibre grating-based sensors functionalised with molecularly imprinted nanoparticles.

Development and validation of a novel fibre-optic respiratory rate sensor (FiRRS) integrated in oxygen delivery devices (2021)
Journal Article
Sinha, R., Hernandez, F., He, C., Korposh, S., Correia, R. N. G., Norris, A., Liu, C., Hayes-Gill, B. R., & Morgan, S. P. (2021). Development and validation of a novel fibre-optic respiratory rate sensor (FiRRS) integrated in oxygen delivery devices. Journal of Physics D: Applied Physics, 54(12), Article 124002. https://doi.org/10.1088/1361-6463/abd061

© 2021 The Author(s). Respiratory rate (RR) monitoring provides crucial information on the overall health condition of patients and a reliable, low cost RR monitor for normal hospital inpatient or home use would be of significant benefit. The propose... Read More about Development and validation of a novel fibre-optic respiratory rate sensor (FiRRS) integrated in oxygen delivery devices.

A Textile Sleeve for Monitoring Oxygen Saturation Using Multichannel Optical Fibre Photoplethysmography (2020)
Journal Article
Ballaji, H. K., Correia, R., Korposh, S., Hayes-Gill, B. R., Hernandez, F. U., Salisbury, B., & Morgan, S. P. (2020). A Textile Sleeve for Monitoring Oxygen Saturation Using Multichannel Optical Fibre Photoplethysmography. Sensors, 20(22), Article 6568. https://doi.org/10.3390/s20226568

Textile-based systems are an attractive prospect for wearable technology as they can provide monitoring of key physiological parameters in a comfortable and unobtrusive form. A novel system based on multichannel optical fibre sensor probes integrated... Read More about A Textile Sleeve for Monitoring Oxygen Saturation Using Multichannel Optical Fibre Photoplethysmography.

A U-Shape Fibre-Optic pH Sensor Based on Hydrogen Bonding of Ethyl Cellulose with a Sol-Gel Matrix (2020)
Journal Article
Tang, Z., Gomez, D., He, C., Korposh, S., Morgan, S. P., Correia, R., Hayes-Gill, B., Setchfield, K., & Liu, L. (2021). A U-Shape Fibre-Optic pH Sensor Based on Hydrogen Bonding of Ethyl Cellulose with a Sol-Gel Matrix. Journal of Lightwave Technology, 39(5), 1557-1564. https://doi.org/10.1109/JLT.2020.3034563

© 1983-2012 IEEE. Development of a biocompatible pH sensor is of importance in biomedical applications, particularly for in vivo measurement, providing necessary information for clinical diagnosis and treatment such as chronic wounds and foetal acido... Read More about A U-Shape Fibre-Optic pH Sensor Based on Hydrogen Bonding of Ethyl Cellulose with a Sol-Gel Matrix.

Surface polymer imprinted optical fibre sensor for dose detection of dabrafenib (2020)
Journal Article
He, C., Ledezma, U. H., Gurnani, P., Albelha, T., Thurecht, K. J., Correia, R., Morgan, S. P., Patel, P., Alexander, C., & Korposh, S. (2020). Surface polymer imprinted optical fibre sensor for dose detection of dabrafenib. Analyst, 145(13), 4504-4511. https://doi.org/10.1039/d0an00434k

© 2020 The Royal Society of Chemistry. Dabrafenib is one of the most widely used of the new generation of targeted anti-cancer drugs. However, its therapeutic window varies for different patients and so there is an unmet need for methods to monitor t... Read More about Surface polymer imprinted optical fibre sensor for dose detection of dabrafenib.

Accurate neonatal heart rate monitoring using a new wireless, cap mounted device (2020)
Journal Article
Henry, C., Shipley, L., Ward, C., Mirahmadi, S., Liu, C., Morgan, S., Crowe, J., Carpenter, J., Hayes-Gill, B., & Sharkey, D. (2020). Accurate neonatal heart rate monitoring using a new wireless, cap mounted device. Acta Paediatrica, 110(1), 72-78. https://doi.org/10.1111/apa.15303

© 2020 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica Aim: A device for newborn heart rate (HR) monitoring at birth that is compatible with delayed cord clamping and minimises hypothermia r... Read More about Accurate neonatal heart rate monitoring using a new wireless, cap mounted device.

Real-Time Humidity Measurement during Sports Activity using Optical Fibre Sensing (2020)
Journal Article
He, C., Korposh, S., Hernandez, F. U., Liu, L., Correia, R., Hayes-Gill, B. R., & Morgan, S. P. (2020). Real-Time Humidity Measurement during Sports Activity using Optical Fibre Sensing. Sensors, 20(7), Article 1904. https://doi.org/10.3390/s20071904

An optical fibre sensor for monitoring relative humidity (RH) changes during exercise is demonstrated. The humidity sensor comprises a tip coating of poly (allylamine hydrochloride) (PAH)/silica nanoparticles (SiO2 NPs) deposited using the layer-by-l... Read More about Real-Time Humidity Measurement during Sports Activity using Optical Fibre Sensing.

Optical fibre sensor for simultaneous measurement of capillary refill time and contact pressure (2020)
Journal Article
Liu, C., Correia, R., Ballaji, H., Korposh, S., Hayes‐gill, B., & Morgan, S. (2020). Optical fibre sensor for simultaneous measurement of capillary refill time and contact pressure. Sensors, 20(5), Article 1388. https://doi.org/10.3390/s20051388

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. The widely applied capillary refill time (CRT) measurement is currently performed by manually applying pressure and using a stopwatch to record the time taken for the skin to recover its norma... Read More about Optical fibre sensor for simultaneous measurement of capillary refill time and contact pressure.

Real time monitoring of biofilm formation on coated medical devices for the reduction and interception of bacterial infections (2020)
Journal Article
Kurmoo, Y., Hook, A. L., Harvey, D., Dubern, J.-F., Williams, P., Morgan, S. P., Korposh, S., & Alexander, M. R. (2020). Real time monitoring of biofilm formation on coated medical devices for the reduction and interception of bacterial infections. Biomaterials Science, 8(5), 1464-1477. https://doi.org/10.1039/c9bm00875f

Real time monitoring of bacterial attachment to medical devices provides opportunities to detect early biofilm formation and instigate appropriate interventions before infection develops. This study utilises long period grating (LPG) optical fibre se... Read More about Real time monitoring of biofilm formation on coated medical devices for the reduction and interception of bacterial infections.

Multi-parameter optical fibre sensing of gaseous ammonia and carbon dioxide (2019)
Journal Article
Liu, L., Morgan, S. P., Correia, R., Lee, S.-W., & Korposh, S. (2020). Multi-parameter optical fibre sensing of gaseous ammonia and carbon dioxide. Journal of Lightwave Technology, 38(7), 2037-2045. https://doi.org/10.1109/jlt.2019.2953271

Ammonia (NH3) and carbon dioxide (CO2) are important breath biomarkers for diagnosis of renal and respiratory diseases. Simultaneous sensing of the two gases is useful for assessment of Helicobacter Pylori infection. This study introduces a multi-par... Read More about Multi-parameter optical fibre sensing of gaseous ammonia and carbon dioxide.

Numerical Simulation of a Scanning Illumination System for Deep Tissue Fluorescence Imaging (2019)
Journal Article
Zhang, Q., Grabowska, A. M., Clarke, P. A., & Morgan, S. P. (2019). Numerical Simulation of a Scanning Illumination System for Deep Tissue Fluorescence Imaging. Journal of Imaging, 5(11), Article 83. https://doi.org/10.3390/jimaging5110083

he spatial resolution and light detected in fluorescence imaging for small animals are limited by light scattering, absorption and autofluorescence. To address this, novel near-infrared fluorescent contrast agents and imaging configurations have been... Read More about Numerical Simulation of a Scanning Illumination System for Deep Tissue Fluorescence Imaging.

Simultaneous in situ temperature and relative humidity monitoring in mechanical ventilators using an array of functionalised optical fibre long period grating sensors (2019)
Journal Article
Hromadka, J., Hazlan, N. N. M., Hernandez, F. U., Correia, R., Norris, A., Morgan, S. P., & Korposh, S. (2019). Simultaneous in situ temperature and relative humidity monitoring in mechanical ventilators using an array of functionalised optical fibre long period grating sensors. Sensors and Actuators B: Chemical, 286, 306 - 314. https://doi.org/10.1016/j.snb.2019.01.124

An array of optical fibre long period gratings (LPGs) has been demonstrated for biomedical application to monitor temperature and relative humidity (RH) changes in the air delivered by a mechanical ventilator operating in different modes. The LPG arr... Read More about Simultaneous in situ temperature and relative humidity monitoring in mechanical ventilators using an array of functionalised optical fibre long period grating sensors.

A reflection-mode fibre-optic sensor for breath carbon dioxide measurement in healthcare (2018)
Journal Article
Liu, L., Hao, F., Morgan, S. P., Correia, R., Norris, A., & Korposh, S. (2019). A reflection-mode fibre-optic sensor for breath carbon dioxide measurement in healthcare. Sensing and Bio-Sensing Research, 22, Article 100254. https://doi.org/10.1016/j.sbsr.2018.100254

A reflection-mode carbon dioxide (CO2) fibre optic sensor (FOS) is developed based on the colorimetric change of pH indicator dye thymol blue. The CO2 sensing film comprises thymol blue and tetramethylammonium hydroxide in the form of an ion pair dop... Read More about A reflection-mode fibre-optic sensor for breath carbon dioxide measurement in healthcare.

Investigation of the performance of hyperspectral imaging by principal component analysis in the prediction of healing of diabetic foot ulcers (2018)
Journal Article
Yang, Q., Sun, S., Jeffcoate, W., Clark, D., Musgove, A., Game, F., & Morgan, S. (2018). Investigation of the performance of hyperspectral imaging by principal component analysis in the prediction of healing of diabetic foot ulcers. Journal of Imaging, 4(12), Article 144. https://doi.org/10.3390/jimaging4120144

Diabetic foot ulcers are a major complication of diabetes and present a considerable burden for both patients and health care providers. As healing often takes many months, a method of determining which ulcers would be most likely to heal would be of... Read More about Investigation of the performance of hyperspectral imaging by principal component analysis in the prediction of healing of diabetic foot ulcers.

Blood pressure estimation from photoplethysmogram and electrocardiogram signals using machine learning (2018)
Presentation / Conference Contribution
Yang, S., Zaki, W., Morgan, S., Cho, S.-Y., Correia, R., Wen, L., & Zhang, Y. (2018, November). Blood pressure estimation from photoplethysmogram and electrocardiogram signals using machine learning. Presented at IET Doctoral Forum on Biomedical Engineering, Healthcare, Robotics and Artificial Intelligence 2018 (BRAIN 2018), Ningbo, China

Blood pressure measurement is a significant part of preventive healthcare and has been widely used in clinical risk and disease management. However, conventional measurement does not provide continuous monitoring and sometimes is inconvenient with a... Read More about Blood pressure estimation from photoplethysmogram and electrocardiogram signals using machine learning.

Mucosal injury following short term tracheal intubation: a novel animal model and composite injury score (2018)
Journal Article
Sinha, R., Correia, R., Gardner, D., Grau-Roma, L., de Brot, S., Hardman, J., Morgan, S., & Norris, A. (2018). Mucosal injury following short term tracheal intubation: a novel animal model and composite injury score. Laryngoscope Investigative Otolaryngology, 3(4), 257-262. https://doi.org/10.1002/lio2.168

Objectives: Postintubation laryngotracheal injury is common. Assessment of histopathological changes currently requires animal models. We set about developing a viable, resource effective animal model to study these effects and to develop a detailed... Read More about Mucosal injury following short term tracheal intubation: a novel animal model and composite injury score.

Biomedical application of optical fibre sensors (2018)
Journal Article
Correia, R., James, S., Lee, S.-W., Morgan, S., & Korposh, S. (2018). Biomedical application of optical fibre sensors. Journal of Optics, 20(7), Article 073003. https://doi.org/10.1088/2040-8986/aac68d

Optical fibre sensors(OFS), as a result of their unique properties such as small size, no interference with electromagnetic radiation, high sensitivity and the ability to design multiplexed or distributed sensing systems, have found applications rang... Read More about Biomedical application of optical fibre sensors.

Highly sensitive label-free antibody detection using a long period fibre grating sensor (2018)
Journal Article
Liu, L., Marques, L., Correia, R., Morgan, S. P., Lee, S.-W., Tighe, P. J., Fairclough, L., & Korposh, S. (2018). Highly sensitive label-free antibody detection using a long period fibre grating sensor. Sensors and Actuators B: Chemical, 271, 24-32. https://doi.org/10.1016/j.snb.2018.05.109

An optical fibre long period grating (LPG) biosensor is appealing in the detection of biomolecules because of the high sensitivity, label-free and real-time measurement. The miniaturized size, ability of remote sensing and immunity to electromagnetic... Read More about Highly sensitive label-free antibody detection using a long period fibre grating sensor.

Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media (2018)
Journal Article
Ahmad, J., Jayet, B., Hill, P. J., Mather, M. L., Dehghani, H., & Morgan, S. P. (in press). Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media. Biomedical Optics Express, 9(4), https://doi.org/10.1364/BOE.9.001664

In vivo imaging of self-illuminating bio-and chemiluminescent reporters is used to observe the physiology of small animals. However, strong light scattering by biological tissues results in poor spatial resolution of the optical imaging, which also d... Read More about Ultrasound-mediation of self-illuminating reporters improves imaging resolution in optically scattering media.