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Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study (2015)
Journal Article
Jenkins, R. G., Simpson, J. K., Saini, G., Bentley, J. H., Russell, A., Braybrooke, R., …Maher, T. M. (2015). Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study. Lancet Respiratory Medicine, 3(6), https://doi.org/10.1016/s2213-2600%2815%2900048-x

BACKGROUND: Idiopathic pulmonary fibrosis, a progressive and inevitably fatal disorder, has a highly variable clinical course. Biomarkers that reflect disease activity are urgently needed to inform patient management and for use as biomarkers of ther... Read More about Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study.

?v?6 integrin may be a potential prognostic biomarker in interstitial lung disease (2015)
Journal Article
Saini, G., Porte, J., Weinreb, P. H., Violette, S. M., Wallace, W. A., McKeever, T. M., & Jenkins, G. (2015). ?v?6 integrin may be a potential prognostic biomarker in interstitial lung disease. European Respiratory Journal, 46(2), 486-494. https://doi.org/10.1183/09031936.00210414

Idiopathic pulmonary fibrosis (IPF) and fibrotic nonspecific interstitial pneumonitis are progressive interstitial lung diseases (ILDs) with limited treatment options and poor survival. However, the rate of disease progression is variable, implying t... Read More about ?v?6 integrin may be a potential prognostic biomarker in interstitial lung disease.

Diverging trends in smoking behaviours according to mental health status (2015)
Journal Article
Szatkowski, L., & McNeill, A. (2015). Diverging trends in smoking behaviours according to mental health status. Nicotine and Tobacco Research, 17(3), https://doi.org/10.1093/ntr/ntu173

Introduction: People with mental health disorders are much more likely to smoke compared to those who do not. This study investigates recent trends in smoking behaviors among both these populations in England. Methods: We used survey responses fro... Read More about Diverging trends in smoking behaviours according to mental health status.

Is there an association between the coverage of immunisation boosters by the age of 5 and deprivation? An ecological study (2015)
Journal Article
Sandford, H., Tata, L. J., Browne, I., & Pritchard, C. (2015). Is there an association between the coverage of immunisation boosters by the age of 5 and deprivation? An ecological study. Vaccine, 33(9), 1218-1222. https://doi.org/10.1016/j.vaccine.2014.12.006

Objective: To determine whether there was an association between the coverage of booster immunisation of Diphtheria, Tetanus, acellular Pertussis and Polio (DTaP/IPV) and second Measles, Mumps and Rubella (MMR) dose by age 5 in accordance with the En... Read More about Is there an association between the coverage of immunisation boosters by the age of 5 and deprivation? An ecological study.

Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial 'in hibernation', ready for rapid activation (2015)
Journal Article
Lim, W. S., Brittain, C., Duley, L., Edwards, S., Gordon, S., Montgomery, A., …Wootton, D. (2015). Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial 'in hibernation', ready for rapid activation. Health Technology Assessment, 19(16), https://doi.org/10.3310/hta19160

Background: There are no completed randomised trials of the use of corticosteroids in patients with severe influenza infection. Corticosteroid use in influenza is widespread, non-systematic and marked by controversy. A recent meta-analysis of observa... Read More about Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial 'in hibernation', ready for rapid activation.

Male involvement and maternal health outcomes: systematic review and meta-analysis (2015)
Journal Article
Yargawa, J., & Leonardi-Bee, J. (2015). Male involvement and maternal health outcomes: systematic review and meta-analysis. Journal of Epidemiology and Community Health, 69(6), 604-612. https://doi.org/10.1136/jech-2014-204784

Background: The developing world accounts for 99% of global maternal deaths. Men in developing countries are the chief decision-makers, determining women's access to maternal health services and influencing their health outcomes. At present, it is un... Read More about Male involvement and maternal health outcomes: systematic review and meta-analysis.

Incidence and distribution of coeliac disease in Campania (Italy): 2011–2013 (2015)
Journal Article
Zingone, F., West, J., Auricchio, R., Maria Bevilacqua, R., Bile, G., Borgheresi, P., …Ciacci, C. (2015). Incidence and distribution of coeliac disease in Campania (Italy): 2011–2013. United European Gastroenterology Journal, 3(2), https://doi.org/10.1177/2050640615571021

BACKGROUND: There exists a wide variation in the reported incidence of coeliac disease in recent decades. We aimed to evaluate the incidence rate of coeliac diagnoses performed in an Italian region, Campania, between 2011 and 2013 and its variation t... Read More about Incidence and distribution of coeliac disease in Campania (Italy): 2011–2013.

Association between psychological distress and liver disease mortality: a meta-analysis of individual study participants (2015)
Journal Article
Russ, T. C., Kivimäki, M., Morling, J. R., Starr, J. M., Stamatakis, E., & Batty, G. D. (in press). Association between psychological distress and liver disease mortality: a meta-analysis of individual study participants. Gastroenterology, 148(5), Article 958-966.e4. https://doi.org/10.1053/j.gastro.2015.02.004

Background & Aims: Risk factors for cardiovascular disease, such as obesity and hypertension, have been associated with non-alcoholic fatty liver disease. Psychological distress (symptoms of anxiety and depression) is a risk factor for cardiovascular... Read More about Association between psychological distress and liver disease mortality: a meta-analysis of individual study participants.

Accuracy of methods for diagnosing atrial fibrillation using 12-lead ECG: a systematic review and meta-analysis (2015)
Journal Article
Taggar, J. S., Coleman, T., Lewis, S., Heneghan, C., & Jones, M. (2015). Accuracy of methods for diagnosing atrial fibrillation using 12-lead ECG: a systematic review and meta-analysis. International Journal of Cardiology, 184, 175-183. https://doi.org/10.1016/j.ijcard.2015.02.014

Background: Screening for atrial fibrillation (AF) using 12-lead-electrocardiograms (ECGs) has been recommended; however, the best method for interpreting ECGs to diagnose AF is not known. We compared accuracy of methods for diagnosing AF from ECGs.... Read More about Accuracy of methods for diagnosing atrial fibrillation using 12-lead ECG: a systematic review and meta-analysis.

Risk of acute appendicitis in and around pregnancy: a population-based cohort study from England (2015)
Journal Article
Zingone, F., Sultan, A. A., Humes, D., & West, J. (2015). Risk of acute appendicitis in and around pregnancy: a population-based cohort study from England. Annals of Surgery, 261(2), https://doi.org/10.1097/sla.0000000000000780

Objective: To determine the absolute and relative risk of acute appendicitis during the antepartum and postpartum periods compared with the time outside pregnancy among women of childbearing age. Background: Acute appendicitis is the most common... Read More about Risk of acute appendicitis in and around pregnancy: a population-based cohort study from England.

Association of socioeconomic status with sex ratio at live birth in individuals living in the slums of Sholapur city, India (2015)
Journal Article
Ahankari, A. S., & Fogarty, A. W. (2015). Association of socioeconomic status with sex ratio at live birth in individuals living in the slums of Sholapur city, India. International journal of medical science and public health, 4(1), https://doi.org/10.5455/ijmsph.2015.1109201428

Background: The existence of female feticide in India is well known. However, limited data are available on the association of socioeconomic status (SES) on sex ratio at live birth in disadvantaged populations, despite the fact that 33% of the popula... Read More about Association of socioeconomic status with sex ratio at live birth in individuals living in the slums of Sholapur city, India.

Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial. (2015)
Journal Article
John, M., Cockcroft, J. R., McKeever, T. M., Coward, W. R., Shale, D. J., Johnson, S. R., …Bolton, C. E. (2015). Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial. International Journal of Chronic Obstructive Pulmonary Disease, 10(1), https://doi.org/10.2147/COPD.S76061

BACKGROUND: There is excess cardiovascular mortality in patients with chronic obstructive pulmonary disease. Aortic stiffness, an independent predictor of cardiovascular risk, and systemic and airway inflammation are increased in patients with the... Read More about Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial..

Adolescents' exposure to tobacco and alcohol content in YouTube music videos (2015)
Journal Article
Cranwell, J., Murray, R., Lewis, S., Leonardi-Bee, J., Dockrell, M., & Britton, J. (in press). Adolescents' exposure to tobacco and alcohol content in YouTube music videos. Addiction, 110(4), https://doi.org/10.1111/add.12835

AIMS: To quantify tobacco and alcohol content, including branding, in popular contemporary YouTube music videos; and measure adolescent exposure to such content. DESIGN: Ten-second interval content analysis of alcohol, tobacco or electronic cigarette... Read More about Adolescents' exposure to tobacco and alcohol content in YouTube music videos.

Pilot study to evaluate a tailored text message intervention for pregnant smokers (MiQuit): study protocol for a randomised controlled trial (2015)
Journal Article
Cooper, S., Foster, K., Naughton, F., Leonardi-Bee, J., Sutton, S., Ussher, M., …Coleman, T. (2015). Pilot study to evaluate a tailored text message intervention for pregnant smokers (MiQuit): study protocol for a randomised controlled trial. Trials, 16, Article 29. https://doi.org/10.1186/S13063-014-0546-4

Background Smoking in pregnancy is a public health problem. Self-help smoking cessation support can help pregnant women to stop smoking, but the effects of delivering this kind of support via SMS text message are not known. A previous randomised... Read More about Pilot study to evaluate a tailored text message intervention for pregnant smokers (MiQuit): study protocol for a randomised controlled trial.

Epidemiology and management of gout in Taiwan: a nationwide population study (2015)
Journal Article
Kuo, C., Grainge, M. J., See, L., Yu, K., Luo, S., Zhang, W., & Doherty, M. (in press). Epidemiology and management of gout in Taiwan: a nationwide population study. Arthritis Research and Therapy, 17(1), https://doi.org/10.1186/s13075-015-0522-8

INTRODUCTION: Gout is the most common inflammatory arthritis worldwide and is the only type of chronic arthritis that potentially can be ‘cured’. However, data on gout incidence, prevalence and management, assessed at multiple time points in the same... Read More about Epidemiology and management of gout in Taiwan: a nationwide population study.

Impact of infection control interventions on rates of Staphylococcus aureus bacteraemia in National Health Service acute hospitals, East Midlands, UK, using interrupted time-series analysis (2015)
Journal Article
Newitt, S., Myles, P. R., Birkin, J., Maskell, V., Slack, R., Nguyen-Van-Tam, J., & Szatkowski, L. (in press). Impact of infection control interventions on rates of Staphylococcus aureus bacteraemia in National Health Service acute hospitals, East Midlands, UK, using interrupted time-series analysis. Journal of Hospital Infection, 90(1), https://doi.org/10.1016/j.jhin.2014.12.016

Background: Reducing healthcare-associated infection (HCAI) is a UK national priority. Multiple national and regional interventions aimed at reduction have been implemented in National Health Service acute hospitals, but assessment of their effective... Read More about Impact of infection control interventions on rates of Staphylococcus aureus bacteraemia in National Health Service acute hospitals, East Midlands, UK, using interrupted time-series analysis.

Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection (2015)
Journal Article
Darch, S. E., McNally, A., Harrison, F., Corander, J., Barr, H. L., Paszkiewicz, K., …Diggle, S. P. (2015). Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection. Scientific Reports, 5, Article 7649. https://doi.org/10.1038/srep07649

The Cystic Fibrosis (CF) lung harbors a complex, polymicrobial ecosystem, in which Pseudomonas aeruginosa is capable of sustaining chronic infections, which are highly resistant to multiple antibiotics. Here, we investigate the phenotypic and genotyp... Read More about Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection.

Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis (2015)
Journal Article
Barr, H. L., Halliday, N., Cámara, M., Barrett, D. A., Williams, P., Forrester, D. L., …Fogarty, A. W. (2015). Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis. European Respiratory Journal, 46(4), 1046-1054. https://doi.org/10.1183/09031936.00225214

Copyright © ERS 2015. Pseudomonas aeruginosa produces quorum sensing signal molecules that are potential biomarkers for infection. A prospective study of 60 cystic fibrosis patients with chronic P. aeruginosa, who required intravenous antibiotics for... Read More about Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis.

Changes in student learning styles over the course of postgraduate taught programmes and the impact of learning styles on achievement in various assessment modes (2015)
Conference Proceeding
Phalkey, R., Pritchard, C., & Myles, P. (2015). Changes in student learning styles over the course of postgraduate taught programmes and the impact of learning styles on achievement in various assessment modes.

Background: The impact of students preferred learning styles on their performance has been investigated in medical and nursing education but little has been done for students enrolling on postgraduate taught programmes in Public Health and Epidemiolo... Read More about Changes in student learning styles over the course of postgraduate taught programmes and the impact of learning styles on achievement in various assessment modes.