Is there an association between the coverage of immunisation boosters by the age of 5 and deprivation? An ecological study

Sandford, Helena; Tata, Laila J.; Browne, Ivan; Pritchard, Catherine

Abstract

Objective: To determine whether there was an association between the coverage of booster immunisation of Diphtheria, Tetanus, acellular Pertussis and Polio (DTaP/IPV) and second Measles, Mumps and Rubella (MMR) dose by age 5 in accordance with the English national immunisation schedule by area-level socioeconomic deprivation and whether this changed between 2007/08 and 2010/11. Design: Ecological study. Data: Routinely collected national Cover of Vaccination Evaluated Rapidly data on immunisation coverage for DTaP/IPV booster and second MMR dose by age 5 and the Index of Multiple Deprivation (IMD). Setting: Primary Care Trust (PCT) areas in England between 2007/08 and 2010/11. Outcome Measures: Population coverage (%) of DTaP/IPV booster and second MMR immunisation by age 5. Results: Over the 4 years among the 9,457,600 children there was an increase in the mean proportion of children being immunised for DTaP/IPV booster and second MMR across England, increasing from 79% (standard deviation (SD12%)) to 86% (SD8%) for DTaP/IPV and 75% (SD10%) to 84% (SD6%) for second MMR between 2007/08 and 2010/11. In 2007/08 the area with lowest DTaP/IPV booster coverage was 31% compared to 54.4% in 2010/11 and for the second MMR in 2007/08 was 39% compared to 64.8% in 2010/11. A weak negative correlation was observed between average IMD score and immunisation coverage for the DTaP/IPV booster which reduced but remained statistically significant over the study period (r = ?0.298, p

Citation

Sandford, H., Tata, L. J., Browne, I., & Pritchard, C. (2015). Is there an association between the coverage of immunisation boosters by the age of 5 and deprivation? An ecological study. Vaccine, 33(9), 1218-1222. https://doi.org/10.1016/j.vaccine.2014.12.006

• Journal Article Type: Article
• Acceptance Date: Dec 7, 2014
• Publication Date: 2015-02
• Deposit Date: Feb 16, 2016
• Publicly Available Date: Feb 16, 2016
• Journal: Vaccine
• Print ISSN: 0264-410X
• Electronic ISSN: 0264-410X
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 33
• Issue: 9
• Pages: 1218-1222
• DOI: https://doi.org/10.1016/j.vaccine.2014.12.006
• Keywords: Immunisation; England; Index of multiple deprivation; Ecological study; Children
• Public URL: https://nottingham-repository.worktribe.com/output/744465
• Publisher URL: http://www.sciencedirect.com/science/article/pii/S0264410X14016338
• Additional Information: This article is maintained by: Elsevier; Article Title: Is there an association between the coverage of immunisation boosters by the age of 5 and deprivation? An ecological study; Journal Title: Vaccine; CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/j.vaccine.2014.12.006; Content Type: article; Copyright: Copyright © 2014 Elsevier Ltd. All rights reserved.