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All Outputs (39)

Identifying key components for a psychological intervention for people with vitiligo: a quantitative and qualitative study in the United Kingdom using web-based questionnaires of people with vitiligo and healthcare professionals (2018)
Journal Article

Background: Psychological interventions are recommended as part of routine management of vitiligo. However, the development and effectiveness of such interventions have been rarely addressed. This study aimed to identify key components for a psycholo... Read More about Identifying key components for a psychological intervention for people with vitiligo: a quantitative and qualitative study in the United Kingdom using web-based questionnaires of people with vitiligo and healthcare professionals.

Risk of bleeding with direct oral anticoagulants versus warfarin: cohort studies using primary care datasets (2018)
Journal Article

Background: There is limited evidence on the safety of direct oral anticoagulants (DOACs) in real world settings. Aim: To investigate risks of bleeding and all-cause mortality in DOACs compared to warfarin. Method: Prospective cohorts of incide... Read More about Risk of bleeding with direct oral anticoagulants versus warfarin: cohort studies using primary care datasets.

Panoptic overview of triple-negative breast cancer in Nigeria: current challenges and promising global initiatives (2018)
Journal Article

Purpose Triple-negative breast cancer (TNBC) is the most deadly form of breast cancer (BC) today. TNBC treatment is fraught with challenges because of the extensive interpatient heterogeneity in clinical behavior and scarcity of stratifying biomar... Read More about Panoptic overview of triple-negative breast cancer in Nigeria: current challenges and promising global initiatives.

Characterizing Microstructural Tissue Properties in Multiple Sclerosis with Diffusion MRI at 7?T and 3?T: The Impact of the Experimental Design (2018)
Journal Article

© 2018 The Author(s) The recent introduction of advanced magnetic resonance (MR) imaging techniques to characterize focal and global degeneration in multiple sclerosis (MS), like the Composite Hindered and Restricted Model of Diffusion, or CHARMED, d... Read More about Characterizing Microstructural Tissue Properties in Multiple Sclerosis with Diffusion MRI at 7?T and 3?T: The Impact of the Experimental Design.

The Developing Human Connectome Project: a minimal processing pipeline for neonatal cortical surface reconstruction (2018)
Journal Article

The Developing Human Connectome Project (dHCP) seeks to create the first 4-dimensional connectome of early life. Understanding this connectome in detail may provide insights into normal as well as abnormal patterns of brain development. Following est... Read More about The Developing Human Connectome Project: a minimal processing pipeline for neonatal cortical surface reconstruction.

The challenges of training, support and assessment of healthcare support workers: a qualitative study of experiences in three English acute hospitals (2017)
Journal Article

Background Ever-growing demands on care systems have increased reliance on healthcare support workers. In the UK, their training has been variable, but organisation-wide failures in care have prompted questions about how this crucial section of the... Read More about The challenges of training, support and assessment of healthcare support workers: a qualitative study of experiences in three English acute hospitals.

Towards a comprehensive framework for movement and distortion correction of diffusion MR images: within volume movement (2017)
Journal Article

Most motion correction methods work by aligning a set of volumes together, or to a volume that represents a reference location. These are based on an implicit assumption that the subject remains motionless during the several seconds it takes to acqui... Read More about Towards a comprehensive framework for movement and distortion correction of diffusion MR images: within volume movement.

CK2 abrogates the inhibitory effects of PRH/HHEX on prostate cancer cell migration and invasion and acts through PRH to control cell proliferation (2017)
Journal Article

PRH/HHEX (Proline Rich Homeodomain protein/Haematopoietically-Expressed Homeobox protein) is a transcription factor that controls cell proliferation, cell differentiation and cell migration. Our previous work has shown that in haematopoietic cells Pr... Read More about CK2 abrogates the inhibitory effects of PRH/HHEX on prostate cancer cell migration and invasion and acts through PRH to control cell proliferation.

Automatic segmentation of human cortical layer-complexes and architectural areas using ex vivo diffusion MRI and its validation (2016)
Journal Article

Recently, several magnetic resonance imaging contrast mechanisms have been shown to distinguish cortical substructure corresponding to selected cortical layers. Here, we investigate cortical layer and area differentiation by automatized unsupervised... Read More about Automatic segmentation of human cortical layer-complexes and architectural areas using ex vivo diffusion MRI and its validation.

Cost-effectiveness of donepezil and memantine in moderate to severe Alzheimer's disease (the DOMINO-AD trial) (2016)
Journal Article

© 2016 The Authors. International Journal of Geriatric Psychiatry published by John Wiley & Sons Ltd. Objective: Most investigations of pharmacotherapy for treating Alzheimer's disease focus on patients with mild-to-moderate symptoms, with little e... Read More about Cost-effectiveness of donepezil and memantine in moderate to severe Alzheimer's disease (the DOMINO-AD trial).