All Outputs (86)

Development of clinical diagnostic criteria for plaque psoriasis in children: an eDelphi consensus study with the International Psoriasis Council (2019)
Journal Article

Psoriasis in children can be a challenging diagnosis: the clinical presentation is often more subtle, may occur in covered sites and can be an unexpected diagnosis as psoriasis if often thought to occur at older ages. Poor recognition and delayed dia... Read More about Development of clinical diagnostic criteria for plaque psoriasis in children: an eDelphi consensus study with the International Psoriasis Council.

Sexual dimorphism of brown adipose tissue function (2019)
Journal Article

Objective To determine whether brown adipose tissue (BAT) activity in school-age children differs between the sexes and to explore the impact of dietary intake, sedentary behavior, and picky/fussy eating. Study design Children aged 8.5-11.8 year... Read More about Sexual dimorphism of brown adipose tissue function.

The mechanisms of pharmacokinetic food-drug interactions: A perspective from the UNGAP group (2019)
Journal Article

The simultaneous intake of food and drugs can have a strong impact on drug release, absorption, distribution, metabolism and/or elimination and consequently, on the efficacy and safety of pharmacotherapy. As such, food-drug interactions are one of th... Read More about The mechanisms of pharmacokinetic food-drug interactions: A perspective from the UNGAP group.

The impact of pre‐operative intravenous iron on quality of life after colorectal cancer surgery: outcomes from the intravenous iron in colorectal cancer‐associated anaemia (IVICA) trial (2019)
Journal Article

Anaemia is associated with a reduction in quality of life, and is common in patients with colorectal cancer . Werecently reported thefindings of the intravenous iron in colorectal cancer-associated anaemia (IVICA) trialcomparing haemoglobin levels an... Read More about The impact of pre‐operative intravenous iron on quality of life after colorectal cancer surgery: outcomes from the intravenous iron in colorectal cancer‐associated anaemia (IVICA) trial.

Levothyroxine in women with thyroid peroxidase antibodies before conception (2019)
Journal Article

Background Thyroid peroxidase antibodies are associated with an increased risk of miscarriage and preterm birth, even when thyroid function is normal. Small trials indicate that the use of levothyroxine could reduce the incidence of such adverse out... Read More about Levothyroxine in women with thyroid peroxidase antibodies before conception.

Predicting fracture risk in patients with chronic obstructive pulmonary disease: a UK-based population-based cohort study (2019)
Journal Article

SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus (2019)
Journal Article

Background: Physical activity and self-monitoring are important for children with type 1 diabetes mellitus (T1DM) but it is unclear whether interventions delivered online are feasible, acceptable to patients and efficacious. The aim was to assess the... Read More about SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus.

Youth drug use in Barbados and England: correlates with online peer influences (2019)
Journal Article

This study examined the relationship between susceptibility to drug-related online peer influence on Facebook and offline alcohol, tobacco, and marijuana use among emerging adults (18-24 years) enrolled at the university level in Barbados and England... Read More about Youth drug use in Barbados and England: correlates with online peer influences.

MRI of the colon in the pharmaceutical field: the future before us (2019)
Journal Article

Oral solid drug formulation is the most common route for administration and it is vital to increase knowledge of the gastrointestinal physiological environment to understand dissolution and absorption processes and to develop reliable biorelevant in... Read More about MRI of the colon in the pharmaceutical field: the future before us.

Innovations in Practice: Avatar‐based virtual reality in CAMHS talking therapy: two exploratory case studies (2019)
Journal Article

Background Avatar‐based virtual reality therapy is an emerging digital technology that can be used to assist the treatment of common mental health problems. This may be particularly appealing to young people who are highly familiar with digital tech... Read More about Innovations in Practice: Avatar‐based virtual reality in CAMHS talking therapy: two exploratory case studies.

An antimicrobial impregnated urinary catheter that reduces mineral encrustation and prevents colonisation by multi-drug resistant organisms for up to 12  weeks (2019)
Journal Article

Two major complications of indwelling urinary catheterisation include infection and mineral encrustation of the catheter. Our antimicrobial urinary catheter (AUC) impregnated with rifampicin, triclosan, and sparfloxacin has demonstrated long-term pro... Read More about An antimicrobial impregnated urinary catheter that reduces mineral encrustation and prevents colonisation by multi-drug resistant organisms for up to 12  weeks.

Gene-based analysis of angiogenesis, mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation (2019)
Journal Article

Cocoa flavanols and fish oil omega-3 fatty acids are two bio-active nutrients that may improve muscle microvascular function, insulin sensitivity and mitochondrial function in older adults. We assessed changes in gene expression of these pathways in... Read More about Gene-based analysis of angiogenesis, mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation.

A Randomized Trial of Prophylactic Antibiotics for Miscarriage Surgery (2019)
Journal Article

© 2019 Massachusetts Medical Society. BACKGROUND Surgical intervention is needed in some cases of spontaneous abortion to remove retained products of conception. Antibiotic prophylaxis may reduce the risk of pelvic infection, which is an important co... Read More about A Randomized Trial of Prophylactic Antibiotics for Miscarriage Surgery.

Misophonia: A scoping review of research (2019)
Journal Article

Objective To scope the literature describing misophonia populations, management, and research opportunities. Method Literature searches for research studies describing patients diagnosed with misophonia, defining a patient profile, or outlining... Read More about Misophonia: A scoping review of research.

DNA damage corrects the aberrant cytoplasmic localisation of nucleophosmin in NPM1 mutated acute myeloid leukaemia (2019)
Journal Article

Targeting mu opioid receptors to modulate gastrointestinal function: what have we learnt so far from the studies in functional bowel disorders? (2019)
Journal Article

Opioids have recently received much attention because of the epidemic in their use in some countries such as the USA and the UK. Concerns have been raised about the possibility that they can increase mortality in patients when used on a long-term bas... Read More about Targeting mu opioid receptors to modulate gastrointestinal function: what have we learnt so far from the studies in functional bowel disorders?.

Toward common data elements for international research in long-term care homes: advancing person-centered care (2019)
Journal Article

To support person-centered, residential long-term care internationally, a consortium of researchers in medicine, nursing, behavioral, and social sciences from 21 geographically and economically diverse countries have launched the WE-THRIVE consortium... Read More about Toward common data elements for international research in long-term care homes: advancing person-centered care.

A systematic review and meta-analysis of decision-making in offender populations with mental disorder (2019)
Journal Article

Decision-making has many different definitions, and is measured in varied ways using neuropsychological tasks. Offenders with mental disorder habitually make disadvantageous decisions, but no study has systematically appraised the literature. This re... Read More about A systematic review and meta-analysis of decision-making in offender populations with mental disorder.

Integrated multi-assay culture model for stem cell chondrogenic differentiation (2019)
Journal Article

Recent osteochondral repair strategies highlight the promise of mesenchymal progenitors, an accessible stem cell source with osteogenic and chondrogenic potential, used in conjunction with biomaterials for tissue engineering. For this, regenerative m... Read More about Integrated multi-assay culture model for stem cell chondrogenic differentiation.

Hierarchical heterogeneity across human cortex shapes large-scale neural dynamics (2019)
Journal Article

The large-scale organization of dynamical neural activity across cortex emerges through long-range interactions among local circuits. We hypothesized that large-scale dynamics are also shaped by heterogeneity of intrinsic local properties across cort... Read More about Hierarchical heterogeneity across human cortex shapes large-scale neural dynamics.