All Outputs (1405)

HABIT: Horse Automated Behaviour Identification Tool: a position paper (2015)
Conference Proceeding

HABIT (Horse Automated Behaviour Identification Tool) is an Animal Computer Interaction (ACI) project, on the interdisciplinary boundary between equitation science and computer science. HABIT will automate the analysis and recognition of horse-to-hor... Read More about HABIT: Horse Automated Behaviour Identification Tool: a position paper.

An investigation of the dynamics of intramammary infections acquired during the dry period on European dairy farms (2015)
Journal Article

The dry period is acknowledged as playing a key role in mastitis epidemiology and yet surprisingly few studies have explored dry period infection dynamics in detail. The aim of this study was to investigate the dynamics of intramammary infection acro... Read More about An investigation of the dynamics of intramammary infections acquired during the dry period on European dairy farms.

Genetics of human and canine dilated cardiomyopathy (2015)
Journal Article

Cardiovascular disease is a leading cause of death in both humans and dogs. Dilated cardiomyopathy (DCM) accounts for a large number of these cases, reported to be the third most common form of cardiac disease in humans and the second most common in... Read More about Genetics of human and canine dilated cardiomyopathy.

The effect of Lameness before and during the breeding season on fertility in 10 pasture-based Irish dairy herds (2015)
Journal Article

Background: The effects of lameness on fertility have been documented frequently but few data are available from seasonally breeding, pasture-based herds (such as those used in Ireland) where cows are housed during the winter months but managed at pa... Read More about The effect of Lameness before and during the breeding season on fertility in 10 pasture-based Irish dairy herds.

Applications and limitations of measuring environmental DNA as indicators of the presence of aquatic animals (2015)
Journal Article

1. In Rees et al. (2014b), we reviewed the current status of environmental DNA (eDN A) tomonitor aquatic populations. Our aim was to focus on discus sion of methodologies used,application of eDNA analysis as a survey tool in ecology, and to include s... Read More about Applications and limitations of measuring environmental DNA as indicators of the presence of aquatic animals.

Use of stochastic simulation to evaluate the reduction in methane emissions and improvement in reproductive efficiency from routine hormonal interventions in dairy herds (2015)
Journal Article

This study predicts the magnitude and between herd variation in changes of methane emissions and production efficiency associated with interventions to improve reproductive efficiency in dairy cows. Data for 10,000 herds of 200 cows were simulated. P... Read More about Use of stochastic simulation to evaluate the reduction in methane emissions and improvement in reproductive efficiency from routine hormonal interventions in dairy herds.

Neuroblastoma arginase activity creates an immunosuppressive microenvironment that impairs autologous and engineered immunity (2015)
Journal Article

Neuroblastoma is the most common extra cranial solid tumour of childhood, and survival remains poor for patients with advanced disease. Novel immune therapies are currently in development, but clinical outcomes have not matched preclinical results. H... Read More about Neuroblastoma arginase activity creates an immunosuppressive microenvironment that impairs autologous and engineered immunity.

Does the Presence of Scrapie Affect the Ability of Current Statutory Discriminatory Tests To Detect the Presence of Bovine Spongiform Encephalopathy? (2015)
Journal Article

Current European Commission (EC) surveillance regulations require discriminatory testing of all transmissible spongiform encephalopathy (TSE)-positive small ruminant (SR) samples in order to classify them as bovine spongiform encephalopathy (BSE) or... Read More about Does the Presence of Scrapie Affect the Ability of Current Statutory Discriminatory Tests To Detect the Presence of Bovine Spongiform Encephalopathy?.

DNA methylation profiling of synovial fluid FLS in rheumatoid arthritis reveals changes common with tissue-derived FLS (2015)
Journal Article

Aims: Alterations in DNA methylation contribute to the abnormal phenotype of fibroblast-like synoviocytes (FLS) from patients with rheumatoid arthritis (RA). Herein, we performed genome-wide DNA methylation profiling of RA FLS derived from synovial f... Read More about DNA methylation profiling of synovial fluid FLS in rheumatoid arthritis reveals changes common with tissue-derived FLS.

Regulation of vascular endothelial growth factor in prostate cancer (2015)
Journal Article

Prostate cancer (PCa) is the most common malignancy affecting men in the western world. Although radical prostatectomy and radiation therapy can successfully treat PCa in the majority of patients, up to ?30% will experience local recurrence or metast... Read More about Regulation of vascular endothelial growth factor in prostate cancer.

Cattle veterinarians' awareness and understanding of biosecurity (2015)
Journal Article

PREVENTIVE biosecurity measures, such as isolation of purchased animals, are well documented in the literature (Duncan 1990, Maunsell and Donovan 2008, Noremark and others 2009) and biosecurity has been highlighted as a key intervention for many of t... Read More about Cattle veterinarians' awareness and understanding of biosecurity.

Semen quality, testicular B-mode and Doppler ultrasound, and serum testosterone concentrations in dogs with established infertility (2015)
Journal Article

Retrospective examination of breeding records enabled the identification of 10 dogs of normal fertility and 10 dogs with established infertility of at least 12 months of duration. Comparisons of testicular palpation, semen evaluation, testicular ultr... Read More about Semen quality, testicular B-mode and Doppler ultrasound, and serum testosterone concentrations in dogs with established infertility.

Opening up animal research and science-society relations?: a thematic analysis of transparency discourses in the United Kingdom (2015)
Journal Article

The use of animals in scientific research represents an interesting case to consider in the context of the contemporary preoccupation with transparency and openness in science and governance. In the United Kingdom, organisations critical of animal re... Read More about Opening up animal research and science-society relations?: a thematic analysis of transparency discourses in the United Kingdom.

Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation (2015)
Journal Article

Acute myeloid leukemia (AML) is characterized by the accumulation of immature blood cell precursors in the bone marrow. Pharmacologically overcoming the differentiation block in this condition is an attractive therapeutic avenue, which has achieved s... Read More about Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation.

Evaluation of treatments for claw horn lesions in dairy cows in a randomized controlled trial (2015)
Journal Article

Lameness is one of the most significant endemic disease problems facing the dairy industry. Claw horn lesions (principally sole hemorrhage, sole ulcer, and white line disease) are some of the most prevalent conditions. Despite the fact that thousands... Read More about Evaluation of treatments for claw horn lesions in dairy cows in a randomized controlled trial.

Circulating microRNAs for the prediction of metastasis in breast cancer patients diagnosed with early stage disease (2015)
Journal Article

Breast cancer is the second most common malignancy diagnosed in women worldwide. The greatest cause of breast cancer mortality is development of metastasis. For many women metastasis is an early event in breast cancer which goes undetected until its... Read More about Circulating microRNAs for the prediction of metastasis in breast cancer patients diagnosed with early stage disease.

Incubation of ovine scrapie with environmental matrix results in biological and biochemical changes of PrPSc over time (2015)
Journal Article

Ovine scrapie can be transmitted via environmental reservoirs. A pool of ovine scrapie isolates were incubated on soil for one day or thirteen months and eluted prion was used to challenge tg338 mice transgenic for ovine PrP. After one-day incubation... Read More about Incubation of ovine scrapie with environmental matrix results in biological and biochemical changes of PrPSc over time.

Sensitive recovery of recombinant antibody clones after their in silico identification within NGS datasets (2015)
Journal Article

Recently the analytical power of the latest high throughput next generation DNA sequencing platforms has been used to analyse phage that have been selected from the panning of large combinatorial libraries displaying either peptide or antibody ligand... Read More about Sensitive recovery of recombinant antibody clones after their in silico identification within NGS datasets.

Poor functional antibody responses are present in nearly all patients with chronic lymphocytic leukaemia, irrespective of total IgG concentration, and are associated with increased risk of infection (2015)
Journal Article

Gestational dietary protein is associated with sex specific decrease in blood flow, fetal heart growth and post-natal blood pressure of progeny (2015)
Journal Article

The incidence of adverse pregnancy outcomes is higher in pregnancies where the fetus is male. Sex specific differences in feto-placental perfusion indices identified by Doppler assessment have recently been associated with placental insufficiency and... Read More about Gestational dietary protein is associated with sex specific decrease in blood flow, fetal heart growth and post-natal blood pressure of progeny.