All Outputs (19)

The endocrine disruptors dibutyl phthalate (DBP) and diethylstilbestrol (DES) influence Leydig cell regeneration following ethane dimethane sulphonate treatment of adult male rats (2011)
Journal Article

The manner by which endocrine-disrupting xenobiotics, such as phthalates, can induce changes in the development of the male reproductive system still remains largely unknown. Herein, we have explored the application of ethane dimethane sulphonate (ED... Read More about The endocrine disruptors dibutyl phthalate (DBP) and diethylstilbestrol (DES) influence Leydig cell regeneration following ethane dimethane sulphonate treatment of adult male rats.

Soybean (Glycine max) Oil Bodies and Their Associated Phytochemicals (2011)
Journal Article

Abstract:? Soybean oil bodies were isolated from 3 cultivars (Ustie, K98, and Elena) and the occurrence of 2 classes of phytochemicals (tocopherol isoforms and isoflavones) and strength of their association with isolated oil bodies was evaluated. Toc... Read More about Soybean (Glycine max) Oil Bodies and Their Associated Phytochemicals.

Myosin heavy chain mRNA isoforms are expressed in two distinct cohorts during C2C12 myogenesis (2011)
Journal Article

The regulation of muscle fibre transitions has mainly been studied in vivo using conventional histological or immunohistochemical techniques. In order to investigate the molecular regulation of myosin heavy chain (MyHC) isoform expression in cell cul... Read More about Myosin heavy chain mRNA isoforms are expressed in two distinct cohorts during C2C12 myogenesis.

Regional variation in angiotensin converting enzyme activity in the human placenta (2011)
Journal Article

Sensitivity of chorionic plate arteries to angiotensin II (AngII) is greatest at the placental periphery. Angiotensin converting enzyme (ACE) is central to the synthesis of AngII and is present in the placental vasculature. We measured vascular ACE a... Read More about Regional variation in angiotensin converting enzyme activity in the human placenta.

Rapid analysis of formic acid, acetic acid, and furfural in pretreated wheat straw hydrolysates and ethanol in a bioethanol fermentation using atmospheric pressure chemical ionisation mass spectrometry (2011)
Journal Article

Atmospheric pressure chemical ionisation mass spectrometry (APCI-MS) offers advantages as a rapid analytical technique for the quantification of three biomass degradation products (acetic acid, formic acid and furfural) within pretreated wheat straw... Read More about Rapid analysis of formic acid, acetic acid, and furfural in pretreated wheat straw hydrolysates and ethanol in a bioethanol fermentation using atmospheric pressure chemical ionisation mass spectrometry.

Application of a bacteriophage cocktail to reduce Salmonella Typhimurium U288 contamination on pig skin (2011)
Journal Article

Multidrug-resistant Salmonella Typhimurium U288 is a significant pathogen of pigs, accounting for over half of all outbreaks on UK pig production premises. The potential of this serovar, and other salmonellae, to enter the food chain during the slaug... Read More about Application of a bacteriophage cocktail to reduce Salmonella Typhimurium U288 contamination on pig skin.

Biological role and clinical significance of insulin-like peptide 3 (2011)
Journal Article

Purpose of Review: Insulin-like peptide 3 (INSL3) is the subject of a fast expanding literature reflecting increasing clinical application, particularly as a diagnostic parameter. This review summarizes the recent INSL3 literature published within th... Read More about Biological role and clinical significance of insulin-like peptide 3.

Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes (2011)
Journal Article

Affymetrix GeneChip microarrays are a powerful tool to study global gene expression profiles and have been used on many species. However, no sheep-specific Affymetrix GeneChip is currently available and the bovine array is fairly limited in its cover... Read More about Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes.

The special systems biology of the sperm (2011)
Journal Article

Spermatozoa represent a highly specialized cell type, with a minimalist structure designed to fulfil a single principal function: the transport of an intact single-copy haploid genome to the site of fertilization in the oviduct, and consequent zygote... Read More about The special systems biology of the sperm.

INSL3 in the ruminant: A powerful indicator of gender- and genetic-specific feto-maternal dialogue (2011)
Journal Article

The hormone Insulin-like peptide 3 (INSL3) is a major secretory product of the Leydig cells from both fetal and adult testes. Consequently, it is a major gender-specific circulating hormone in the male fetus, where it is responsible for the first pha... Read More about INSL3 in the ruminant: A powerful indicator of gender- and genetic-specific feto-maternal dialogue.

Calpastatin is associated with lymphovascular invasion in breast cancer (2011)
Journal Article

Metastasis of breast cancer is a major contributor to mortality. Histological assessment of vascular invasion (VI) provides important prognostic information and demonstrates that VI occurs predominantly via lymphatics in breast cancer. We sought to e... Read More about Calpastatin is associated with lymphovascular invasion in breast cancer.

The interactions of CO2, ethanol, hop acids and sweetener on flavour perception in a model beer (2011)
Journal Article

Beer is a complex beverage. Beer flavour is a multisensory experience in which, in addition to aroma volatiles, CO2, ethanol, bitterness (hop acids) and sweetness all contribute. To investigate the interactions between these fundamental components, a... Read More about The interactions of CO2, ethanol, hop acids and sweetener on flavour perception in a model beer.

Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. I. Regulation of myogenesis and environmental impact (2011)
Journal Article

Skeletal muscle development in vertebrates - also termed myogenesis - is a highly integrated process. Evidence to date indicates that the processes are very similar across mammals, poultry and fish, although the timings of the various steps differ co... Read More about Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. I. Regulation of myogenesis and environmental impact.

The calpain system and cancer (2011)
Journal Article

The calpains are a conserved family of cysteine proteinases that catalyse the controlled proteolysis of many specific substrates. Calpain activity is implicated in several fundamental physiological processes, including cytoskeletal remodelling, cellu... Read More about The calpain system and cancer.

Aroma encapsulation and aroma delivery by oil body suspensions derived from sunflower seeds (Helianthus annus) (2011)
Journal Article

Oil bodies are small discrete cell organelles that can be found within oilseeds. Oil bodies have been investigated previously as a potential technology platform for use within the food industry, offering stable, antioxidant-enriched lipid-delivery... Read More about Aroma encapsulation and aroma delivery by oil body suspensions derived from sunflower seeds (Helianthus annus).

Histaminergic regulation of seasonal metabolic rhythms in Siberian hamsters (2011)
Journal Article

We investigated whether histaminergic tone contributes to the seasonal catabolic state in Siberian hamsters by determining the effect of ablation of histaminergic neurons on food intake, metabolic rate and body weight. A ribosomal toxin (saporin) con... Read More about Histaminergic regulation of seasonal metabolic rhythms in Siberian hamsters.

Hydrogen sulfide and cell signaling (2011)
Journal Article

Hydrogen sulfide (H2S) is a gaseous mediator synthesized from cysteine by cystathionine λ lyase (CSE) and other naturally occurring enzymes. Pharmacological experiments usingH2S donors and genetic experiments using CSE knockout mice suggest important... Read More about Hydrogen sulfide and cell signaling.

Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. II - Genetic factors related to animal performance and advances in methodology (2011)
Journal Article

Selective breeding is an effective tool to improve livestock. Several selection experiments have been conducted to study direct selection responses as well as correlated responses in traits of skeletal muscle growth and function. Moreover, comparison... Read More about Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. II - Genetic factors related to animal performance and advances in methodology.

Effects of Ethanol, Carbonation and Hop Acids on Volatile Delivery in a Model Beer System (2011)
Journal Article

A model beer was created to investigate the effects of ethanol, carbonation and hop acids on volatile release (ethyl acetate, isoamyl alcohol and phenethyl alcohol) using both headspace analysis and in?nose measurement during consumption. None of the... Read More about Effects of Ethanol, Carbonation and Hop Acids on Volatile Delivery in a Model Beer System.