All Outputs (38)

Hippocampal disinhibition reduces contextual and elemental fear conditioning while sparing the acquisition of latent inhibition (2021)
Working Paper

Hippocampal neural disinhibition, i.e. reduced GABAergic inhibition, is a key feature of schizophrenia pathophysiology. The hippocampus is an important part of the neural circuitry that controls fear conditioning and can also modulate prefrontal and... Read More about Hippocampal disinhibition reduces contextual and elemental fear conditioning while sparing the acquisition of latent inhibition.

DNA methylation changes during long-term in vitro cell culture are caused by epigenetic drift (2021)
Journal Article

Culture expansion of primary cells evokes highly reproducible DNA methylation (DNAm) changes. We have identified CG dinucleotides (CpGs) that become continuously hyper- or hypomethylated during long-term culture of mesenchymal stem cells (MSCs) and o... Read More about DNA methylation changes during long-term in vitro cell culture are caused by epigenetic drift.

Mechanisms of umami taste perception: From molecular level to brain imaging (2021)
Journal Article

Due to unique characteristics, umami substances have gained much attention in the food industry during the past decade as potential replacers to sodium or fat to increase food palatability. Umami is not only known to increase appetite, but also to in... Read More about Mechanisms of umami taste perception: From molecular level to brain imaging.

Application of sodium selenate to cowpea (Vigna unguiculata L.) increases shoot and grain Se partitioning with strong genotypic interactions (2021)
Journal Article

Backgorund: Cowpea is a crop widely used in developing countries due its rusticity. Besides its rich genotypic variability, most breeding programs do not explore its potential to improve elements uptake. Selenium (Se) is a scarce element in most soil... Read More about Application of sodium selenate to cowpea (Vigna unguiculata L.) increases shoot and grain Se partitioning with strong genotypic interactions.

Environmental and human iodine and selenium status: lessons from Gilgit-Baltistan, North-East Pakistan (2021)
Journal Article

Iodine and selenium deficiencies are common worldwide. We assessed the iodine and selenium status of Gilgit-Baltistan, Pakistan. We determined the elemental composition (ICP-MS) of locally grown crops (n = 281), drinking water (n = 82), urine (n = 45... Read More about Environmental and human iodine and selenium status: lessons from Gilgit-Baltistan, North-East Pakistan.

Reply to: Timing of puberty — body size or reproductive optimization? (2021)
Journal Article

Magnesium and calcium overaccumulate in the leaves of a schengen3 mutant of Brassica rapa (2021)
Journal Article

Magnesium (Mg) and calcium (Ca) are essential mineral nutrients poorly supplied in many human food systems. In grazing livestock, Mg and Ca deficiencies are costly welfare issues. Here, we report a Brassica rapa loss-of-function schengen3 (sgn3) muta... Read More about Magnesium and calcium overaccumulate in the leaves of a schengen3 mutant of Brassica rapa.

Terpene polyacrylate TPA5 shows favorable molecular hydrodynamic properties as a potential bioinspired archaeological wood consolidant (2021)
Journal Article

There is currently a pressing need for the development of novel bioinspired consolidants for waterlogged, archaeological wood. Bioinspired materials possess many advantages, such as biocompatibility and sustainability, which makes them ideal to use i... Read More about Terpene polyacrylate TPA5 shows favorable molecular hydrodynamic properties as a potential bioinspired archaeological wood consolidant.

On the contribution of malt quality and the malting process to the formation of beer staling aldehydes: a review (2021)
Journal Article

Despite decades of extensive research, beer flavour instability remains a challenge for both brewing and malting industries. Malt impacts the brewing process as well as the quality of the final beer. It also affects the stability of beer flavour, as... Read More about On the contribution of malt quality and the malting process to the formation of beer staling aldehydes: a review.

Male seminal parameters are not associated with Leydig cell functional capacity in men (2021)
Journal Article

Background: Insulin-like peptide 3 (INSL3) is a constitutive, secreted peptide produced in the male uniquely by the Leydig cells of the testes. It is a biomarker for Leydig cell functional capacity, which is a measure of the numbers and differentiati... Read More about Male seminal parameters are not associated with Leydig cell functional capacity in men.

Energy-restricted interventions are effective for the remission of newly diagnosed type 2 diabetes: A systematic review of the evidence base (2021)
Journal Article

Background: Type 2 diabetes (T2DM) is a chronic, progressive disease. Caloric restriction and subsequent weight loss have been associated with both improvements and, in some cases, remission of T2DM. Aim: To systematically review the safety and ef... Read More about Energy-restricted interventions are effective for the remission of newly diagnosed type 2 diabetes: A systematic review of the evidence base.

Impact of mixed feedstock of wheat straw, willow and Miscanthus on enzymatic hydrolysis and inhibitor production after microwave hydrothermal pre-treatment in Europe (2021)
Journal Article

Lignocellulosic feedstocks for biorefinery are likely to be seasonal and the supply of feedstock to cellulosic biorefineries remains a challenge. One way to overcome this is by utilizing a mixed feedstock which facilitates the maintenance of a year-r... Read More about Impact of mixed feedstock of wheat straw, willow and Miscanthus on enzymatic hydrolysis and inhibitor production after microwave hydrothermal pre-treatment in Europe.

Arabidopsis thaliana zinc accumulation in leaf trichomes is correlated with zinc concentration in leaves (2021)
Journal Article

Zinc (Zn) is a key micronutrient for plants and animals, and understanding Zn homeostasis in plants can improve both agriculture and human health. While root Zn transporters in plant model species have been characterized in detail, comparatively litt... Read More about Arabidopsis thaliana zinc accumulation in leaf trichomes is correlated with zinc concentration in leaves.

Acetate and auto-inducing peptide are independent triggers of quorum sensing in Lactobacillus plantarum (2021)
Journal Article

The synthesis of plantaricin in Lactobacillus plantarum is regulated by quorum sensing. However, the nature of the extra-cytoplasmic (EC) sensing domain of the histidine kinase (PlnB1) and the ability to recognize the auto-inducing peptide PlnA1 is n... Read More about Acetate and auto-inducing peptide are independent triggers of quorum sensing in Lactobacillus plantarum.

Function of the pseudo phosphotransfer proteins has diverged between rice and Arabidopsis (2021)
Journal Article

© 2021 The Authors. The Plant Journal published by Society for Experimental Biology and John Wiley & Sons Ltd. The phytohormone cytokinin plays a significant role in nearly all aspects of plant growth and development. Cytokinin signaling has primar... Read More about Function of the pseudo phosphotransfer proteins has diverged between rice and Arabidopsis.

1,135 ionomes reveals the global pattern of leaf and seed mineral nutrient and trace element diversity in Arabidopsis thaliana (2021)
Journal Article

Soil is a heterogenous reservoir of essential elements needed for plant growth and development. Plants have evolved mechanisms to balance their nutritional needs based on availability of nutrients. This has led to genetically‐based variation in the e... Read More about 1,135 ionomes reveals the global pattern of leaf and seed mineral nutrient and trace element diversity in Arabidopsis thaliana.

A Novel Signaling Pathway Required for Arabidopsis Endodermal Root Organization Shapes the Rhizosphere Microbiome (2021)
Journal Article

Plant roots sense soil compaction through restricted ethylene diffusion (2021)
Journal Article

© 2021 The Authors, some rights reserved. Soil compaction represents a major challenge for modern agriculture. Compaction is intuitively thought to reduce root growth by limiting the ability of roots to penetrate harder soils. We report that root gro... Read More about Plant roots sense soil compaction through restricted ethylene diffusion.