The mechanism underlying activation of factor IX by factor XIa
(2014)
Journal Article
Gailani, D., Geng, Y., Verhamme, I., Sun, M., Bajaj, S. P., Messer, A., & Emsley, J. (2014). The mechanism underlying activation of factor IX by factor XIa. Thrombosis Research, 133(Supplement 1), S48-S51. doi:10.1016/j.thromres.2014.03.020
Factor XI (fXI) is the zymogen of a plasma protease, factor XIa (fXIa), that contributes to thrombin generation during blood coagulation by proteolytic conversion of factor IX (fIX) to factor IXa? (fIXa?). There is considerable interest in fXIa as a... Read More about The mechanism underlying activation of factor IX by factor XIa.