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Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment

Hook, Andrew L.; Chang, Chien?Yi; Scurr, David J.; Langer, Robert; Anderson, Daniel G.; Williams, Paul; Davies, Martyn C.; Alexander, Morgan R.

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Authors

ANDREW HOOK ANDREW.HOOK@NOTTINGHAM.AC.UK
Assistant Professor

Chien?Yi Chang

DAVID SCURR DAVID.SCURR@NOTTINGHAM.AC.UK
Principal Research Fellow

Robert Langer

Daniel G. Anderson

PAUL WILLIAMS PAUL.WILLIAMS@NOTTINGHAM.AC.UK
Professor of Molecular Microbiology

Martyn C. Davies

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MORGAN ALEXANDER MORGAN.ALEXANDER@NOTTINGHAM.AC.UK
Professor of Biomedical Surfaces



Abstract

The thermally triggered release of up to 96% of attached uropathogenic E. coli is achieved on two polymers with opposite changes in surface wettability upon reduction in temperature. This demonstrates that the bacterial attachment to a surface cannot be explained in terms of water contact angle alone; rather, the surface composition of the polymer plays the key role.

Citation

Hook, A. L., Chang, C., Scurr, D. J., Langer, R., Anderson, D. G., Williams, P., …Alexander, M. R. (2014). Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment. Advanced Healthcare Materials, 3(7), 1020-1025. https://doi.org/10.1002/adhm.201300518

Journal Article Type Article
Acceptance Date Feb 4, 2014
Online Publication Date Feb 4, 2014
Publication Date 2014-07
Deposit Date Jun 21, 2018
Publicly Available Date Mar 28, 2024
Journal Advanced Healthcare Materials
Print ISSN 2192-2640
Electronic ISSN 2192-2659
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 3
Issue 7
Pages 1020-1025
DOI https://doi.org/10.1002/adhm.201300518
Keywords switchable polymers; thermal responsiveness; ToF?SIMS; Escherichia coli
Public URL https://nottingham-repository.worktribe.com/output/1102081
Publisher URL https://onlinelibrary.wiley.com/doi/full/10.1002/adhm.201300518
PMID 24497458

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