All Outputs (144)

Experiences of receiving a diagnosis of multiple sclerosis: a meta-synthesis of qualitative studies (2022)
Journal Article

Purpose: This meta-synthesis aimed to synthesise qualitative evidence on experiences of people with Multiple Sclerosis (MS) in receiving a diagnosis, to derive a conceptual understanding of adjustment to MS diagnosis. Methods: Five electronic databas... Read More about Experiences of receiving a diagnosis of multiple sclerosis: a meta-synthesis of qualitative studies.

Acceptability of a nurse-led non-pharmacological complex intervention for knee pain: Nurse and patient views and experiences (2022)
Journal Article

Objectives The overall purpose of this research programme is to develop and test the feasibility of a complex intervention for knee pain delivered by a nurse, and comprising both non-pharmacological and pharmacological interventions. In this first ph... Read More about Acceptability of a nurse-led non-pharmacological complex intervention for knee pain: Nurse and patient views and experiences.

Memory rehabilitation for people with multiple sclerosis (2021)
Journal Article

Background Problems with cognition, particularly memory, are common in people with multiple sclerosis (MS) and can affect their ability to complete daily activities and can negatively affect quality of life. Over the last few years, there has been c... Read More about Memory rehabilitation for people with multiple sclerosis.

COVID-19 in Multiple Sclerosis: Clinically reported outcomes from the UK Multiple Sclerosis Register (2021)
Journal Article

Background: In March 2020, the United Kingdom Multiple Sclerosis Register (UKMSR) established an electronic case return form, designed collaboratively by MS neurologists, to record data about COVID-19 infections in people with MS (pwMS). Objectives:... Read More about COVID-19 in Multiple Sclerosis: Clinically reported outcomes from the UK Multiple Sclerosis Register.

Improving smoking cessation support for people with multiple sclerosis: A qualitative analysis of clinicians’ views and current practice (2021)
Journal Article

Introduction Smoking is a key modifiable risk factor in multiple sclerosis (MS). MS healthcare providers have a central role informing people of the deleterious effects of smoking on MS progression and promote smoking cessation, yet there is limited... Read More about Improving smoking cessation support for people with multiple sclerosis: A qualitative analysis of clinicians’ views and current practice.

Managing post-stroke fatigue: A qualitative study to explore multifaceted clinical perspectives (2021)
Journal Article

Introduction: Post-stroke fatigue (PSF) is common and debilitating. However, while its effective management is a priority for clinicians and stroke survivors, there remains little evidence to provide guidance or underpin practice. Our aim, therefore,... Read More about Managing post-stroke fatigue: A qualitative study to explore multifaceted clinical perspectives.

A single-case experimental evaluation of a new group-based intervention to enhance adjustment to life with acquired brain injury: VaLiANT (valued living after neurological trauma) (2021)
Journal Article

Adjustment to life with acquired brain injury (ABI) requires self-identity and behaviour to be updated, incorporating injury-related changes. Identifying and enabling new values-consistent behaviours could facilitate this process. We evaluated the fe... Read More about A single-case experimental evaluation of a new group-based intervention to enhance adjustment to life with acquired brain injury: VaLiANT (valued living after neurological trauma).

Fidelity assessment of nurse-led non-pharmacological package of care for knee pain in the package development phase of a feasibility randomised controlled trial based in secondary care: A mixed methods study (2021)
Journal Article

Objectives To evaluate fidelity of delivery of a nurse-led non-pharmacological complex intervention for knee pain. Setting Secondary care. Single-centre study. Study design Mixed methods study. Participants Eighteen adults with chronic knee pain. Inc... Read More about Fidelity assessment of nurse-led non-pharmacological package of care for knee pain in the package development phase of a feasibility randomised controlled trial based in secondary care: A mixed methods study.

Acceptance-based telephone support around the time of transition to secondary progressive multiple sclerosis: A feasibility randomised controlled trial (2021)
Journal Article

Introduction Transitioning to secondary progressive multiple sclerosis (SPMS) is a difficult time for people, fraught with psychological uncertainty and an increase in physical disability. In parallel, healthcare appointments become less frequent, m... Read More about Acceptance-based telephone support around the time of transition to secondary progressive multiple sclerosis: A feasibility randomised controlled trial.

Barriers and motivators for tobacco smoking cessation in people with multiple sclerosis (2021)
Journal Article

Introduction Smoking is a key modifiable risk factor for health outcomes of people with multiple sclerosis (MS). Little evidence exists on whether the information and support needs of people with MS who smoke are met. This study aimed to explore kno... Read More about Barriers and motivators for tobacco smoking cessation in people with multiple sclerosis.

Cognitive measures used in adults with multiple sclerosis: A systematic review (2021)
Journal Article

Cognitive problems are common in people with Multiple Sclerosis (MS), and researchers and clinicians have used a vast array of measures to assess cognition. Our aim was to systematically identify cognitive measures routinely used in MS research, and... Read More about Cognitive measures used in adults with multiple sclerosis: A systematic review.

Mental health of people with multiple sclerosis during the COVID-19 outbreak: A prospective cohort and cross-sectional case–control study of the UK MS Register (2021)
Journal Article

Background: People with MS (pwMS) have had higher rates of anxiety and depression than the general population before the COVID-19 pandemic, placing them at higher risk of experiencing poor psychological wellbeing during the pandemic. Objective: To as... Read More about Mental health of people with multiple sclerosis during the COVID-19 outbreak: A prospective cohort and cross-sectional case–control study of the UK MS Register.

Magnetoencephalography abnormalities in adult mild traumatic brain injury: a systematic review (2021)
Journal Article

COVID-19 is associated with new symptoms of multiple sclerosis that are prevented by disease modifying therapies (2021)
Journal Article

Background Infections can trigger exacerbations of multiple sclerosis (MS). The effects of the coronavirus disease 2019 (COVID-19) on MS are not known. The aim of this study was to understand the impact of COVID-19 on new and pre-existing symptoms... Read More about COVID-19 is associated with new symptoms of multiple sclerosis that are prevented by disease modifying therapies.

Cognitive assessment in multiple sclerosis clinical care: A qualitative evaluation of stakeholder perceptions and preferences (2021)
Journal Article

There is a growing consensus that cognitive assessments should form part of routine clinical care in Multiple Sclerosis (MS). However, what remains unclear is which assessments are preferred by “stakeholders” (including people with MS, family members... Read More about Cognitive assessment in multiple sclerosis clinical care: A qualitative evaluation of stakeholder perceptions and preferences.

The Central Aspects of Pain in the Knee (CAP-Knee) questionnaire; a mixed-methods study of a self-report instrument for assessing central mechanisms in people with knee pain (2021)
Journal Article

OBJECTIVES: Pain is the prevailing symptom of knee osteoarthritis. Central sensitisation creates discordance between pain and joint pathology. We previously reported a central pain mechanisms trait derived from 8 discrete characteristics: neuropathic... Read More about The Central Aspects of Pain in the Knee (CAP-Knee) questionnaire; a mixed-methods study of a self-report instrument for assessing central mechanisms in people with knee pain.

Vocational rehabilitation to enhance return to work after trauma (ROWTATE): protocol for a non-randomised single-arm mixed-methods feasibility study (2021)
Journal Article

Background Traumatic injuries are common amongst working age adults. Survivors often experience physical and psychological problems, reduced quality of life and difficulty returning to work. Vocational rehabilitation improves work outcomes for a ran... Read More about Vocational rehabilitation to enhance return to work after trauma (ROWTATE): protocol for a non-randomised single-arm mixed-methods feasibility study.

The evidence for cognitive behavioural therapy in any condition, population or context: a meta-review of systematic reviews and panoramic meta-analysis (2021)
Journal Article

The majority of psychological treatment research is dedicated to investigating the effectiveness of cognitive behavioural therapy (CBT) across different conditions, population and contexts. We aimed to summarise the current systematic review evidence... Read More about The evidence for cognitive behavioural therapy in any condition, population or context: a meta-review of systematic reviews and panoramic meta-analysis.

Dorsolateral prefrontal circuit effective connectivity mediates the relationship between white matter structure and PASAT‐3 performance in multiple sclerosis (2020)
Journal Article

Three decades ago a series of parallel circuits were described involving the frontal cortex and deep grey matter structures, with putative roles in control of motor and oculomotor function, cognition, behaviour and emotion. The circuit comprising the... Read More about Dorsolateral prefrontal circuit effective connectivity mediates the relationship between white matter structure and PASAT‐3 performance in multiple sclerosis.

Developing a clinical pathway to identify and manage cognitive problems in Multiple Sclerosis: Qualitative findings from patients, family members, charity volunteers, clinicians and healthcare commissioners (2020)
Journal Article

Background: Cognitive problems are a common and debilitating symptom of multiple sclerosis (MS). Screening and treatment for cognitive problems are recommended, however these are not routinely delivered in UK clinics. We collected and synthesised... Read More about Developing a clinical pathway to identify and manage cognitive problems in Multiple Sclerosis: Qualitative findings from patients, family members, charity volunteers, clinicians and healthcare commissioners.