Afagh Garjani
Mental health of people with multiple sclerosis during the COVID-19 outbreak: A prospective cohort and cross-sectional case–control study of the UK MS Register
Garjani, Afagh; Hunter, Rachael; Law, Graham R; Middleton, Rodden M; Tuite-Dalton, Katherine A; Dobson, Ruth; Ford, David V; Hughes, Stella; Pearson, Owen R; Rog, David; Tallantyre, Emma C; Nicholas, Richard; Morriss, Richard; Evangelou, Nikos; das Nair, Roshan
Authors
Rachael Hunter
Graham R Law
Rodden M Middleton
Katherine A Tuite-Dalton
Ruth Dobson
David V Ford
Stella Hughes
Owen R Pearson
David Rog
Emma C Tallantyre
Richard Nicholas
RICHARD MORRISS richard.morriss@nottingham.ac.uk
Professor of Psychiatry and Community Mental Health
NIKOS EVANGELOU Nikos.Evangelou@nottingham.ac.uk
Clinical Professor
ROSHAN NAIR Roshan.dasnair@nottingham.ac.uk
Professor of Clinical Psychology and Neuropsychology
Abstract
Background: People with MS (pwMS) have had higher rates of anxiety and depression than the general population before the COVID-19 pandemic, placing them at higher risk of experiencing poor psychological wellbeing during the pandemic. Objective: To assess mental health and its social/lifestyle determinants in pwMS during the first wave of the outbreak in the United Kingdom. Methods: This is a community-based, prospective longitudinal cohort and cross-sectional case–control online questionnaire study. It includes 2010 pwMS from the UK MS Register and 380 people without MS. Results: The Hospital Anxiety and Depression Scale scores of pwMS for anxiety and depression during the outbreak did not change from the previous year. PwMS were more likely to have anxiety (using General Anxiety Disorder-7) and/or depression (using Patient Health Questionnaire-9) than controls during the outbreak (OR: 2.14, 95% CI: 1.58–2.91). PwMS felt lonelier (OR: 1.37, 95% CI: 1.04–1.80) reported worse social support (OR: 1.90, 95% CI: 1.18–3.07) and reported worsened exercise habits (OR: 1.65, 95% CI: 1.18–2.32) during the outbreak than controls. Conclusion: Early in the pandemic, pwMS remained at higher risk of experiencing anxiety and depression than the general population. It is important that multidisciplinary teams improve their support for the wellbeing of pwMS, who are vulnerable to the negative effects of the pandemic on their lifestyle and social support.
Citation
Garjani, A., Hunter, R., Law, G. R., Middleton, R. M., Tuite-Dalton, K. A., Dobson, R., …das Nair, R. (2022). Mental health of people with multiple sclerosis during the COVID-19 outbreak: A prospective cohort and cross-sectional case–control study of the UK MS Register. Multiple Sclerosis Journal, 28(7), 1060-1071. https://doi.org/10.1177/13524585211020435
Journal Article Type | Article |
---|---|
Acceptance Date | May 7, 2021 |
Online Publication Date | Jun 3, 2021 |
Publication Date | 2022-06 |
Deposit Date | May 25, 2021 |
Publicly Available Date | Jun 3, 2021 |
Journal | Multiple Sclerosis Journal |
Print ISSN | 1352-4585 |
Electronic ISSN | 1477-0970 |
Peer Reviewed | Peer Reviewed |
Volume | 28 |
Issue | 7 |
Pages | 1060-1071 |
DOI | https://doi.org/10.1177/13524585211020435 |
Keywords | Neurology; Clinical Neurology |
Public URL | https://nottingham-repository.worktribe.com/output/5570987 |
Publisher URL | https://journals.sagepub.com/doi/10.1177/13524585211020435 |
Additional Information | Reuse is restricted to non-commercial and no derivative uses. |
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