Skip to main content

Research Repository

Advanced Search

All Outputs (17)

The long and short of it: benchmarking viromics using Illumina, Nanopore and PacBio sequencing technologies (2024)
Journal Article

Viral metagenomics has fuelled a rapid change in our understanding of global viral diversity and ecology. Long-read sequencing and hybrid assembly approaches that combine long- and short-read technologies are now being widely implemented in bacterial... Read More about The long and short of it: benchmarking viromics using Illumina, Nanopore and PacBio sequencing technologies.

Hybrid assembly of an agricultural slurry virome reveals a diverse and stable community with the potential to alter the metabolism and virulence of veterinary pathogens (2021)
Journal Article

Viruses are the most abundant biological entities on Earth, known to be crucial components of microbial ecosystems. However, there is little information on the viral community within agricultural waste. There are currently ~ 2.7 million dairy cattle... Read More about Hybrid assembly of an agricultural slurry virome reveals a diverse and stable community with the potential to alter the metabolism and virulence of veterinary pathogens.

A model of persistent Salmonella infection: Salmonella pullorum modulates the immune response of the chicken from a Th17 towards a Th2-type response (2018)
Journal Article

Salmonella enterica infection affects a wide range of animals and human and a small number of serovars cause typhoid-like infections, one characteristic of which is persistent infection in convalescents. The avian specific serovar S Pullorum produces... Read More about A model of persistent Salmonella infection: Salmonella pullorum modulates the immune response of the chicken from a Th17 towards a Th2-type response.

Novel inflammatory cell infiltration scoring system to investigate healthy and footrot affected ovine interdigital skin (2018)
Journal Article

Ovine footrot is a degenerative disease of sheep feet leading to the separation of hoofhorn from the underlying skin and lameness. This study quantitatively examined histological features of the ovine interdigital skin as well as their relationship w... Read More about Novel inflammatory cell infiltration scoring system to investigate healthy and footrot affected ovine interdigital skin.

The Uses of Medievalism in Early Modern England: Recovery, Temporality, and the “Passionating” of the Past (2018)
Journal Article

The premodern past was desired and deployed in a myriad of different ways in sixteenth-century England. The period of the English Reformations produced a generative, complex, and paradoxical range of feelings for the premodern. Many sixteenth-century... Read More about The Uses of Medievalism in Early Modern England: Recovery, Temporality, and the “Passionating” of the Past.

Erratum for Aidley et al., “Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations” (2017)
Journal Article

© 2017 Aidley et al. Volume 8, no. 2, e02311-16, 2017, https://doi.org/10.1128/mBio.02311-16. The byline and affiliation line of our article should appear as shown above. The following should also be added to the end of Acknowledgments: “M.A.J. was s... Read More about Erratum for Aidley et al., “Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations”.

Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations (2017)
Journal Article

Phase variation occurs in many pathogenic and commensal bacteria and is a major generator of genetic variability. A putative advantage of phase variation is to counter reductions in variability imposed by nonselective bottlenecks during transmission.... Read More about Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations.

High throughput method for analysis of repeat number for 28 phase variable loci of C. jejuni strain NCTC11168 (2016)
Journal Article

Mutations in simple sequence repeat tracts are a major mechanism of phase variation in several bacterial species including Campylobacter jejuni. Changes in repeat number of tracts located within the reading frame can produce a high frequency of rever... Read More about High throughput method for analysis of repeat number for 28 phase variable loci of C. jejuni strain NCTC11168.

Campylobacter jejuni PflB is required for motility and colonisation of the chicken gastrointestinal tract (2015)
Journal Article

Campylobacter jejuni is the leading cause of foodborne bacterial gastroenteritis worldwide. Although the mechanisms by which C. jejuni causes disease are not completely understood, the presence of functional flagella appears to be required for coloni... Read More about Campylobacter jejuni PflB is required for motility and colonisation of the chicken gastrointestinal tract.

CapA, an Autotransporter Protein of Campylobacter jejuni, Mediates Association with Human Epithelial Cells and Colonization of the Chicken Gut (2007)
Journal Article

Two putative autotransporter proteins, CapA and CapB, were identified in silico from the genome sequence of Campylobacter jejuni NCTC11168. The genes encoding each protein contain homopolymeric tracts, suggestive of phase variation mediated by a slip... Read More about CapA, an Autotransporter Protein of Campylobacter jejuni, Mediates Association with Human Epithelial Cells and Colonization of the Chicken Gut.