All Outputs (109)

Outcomes after non-operative management of perforated diverticular disease: a population-based cohort study (2021)
Journal Article

BACKGROUND: The management of perforated diverticular disease has changed in the past 10 years with a move towards less surgical intervention. This population-based cohort study aimed to define the risk of death and readmission following non-operativ... Read More about Outcomes after non-operative management of perforated diverticular disease: a population-based cohort study.

We need stronger evidence for (or against) hepatocellular carcinoma surveillance (2021)
Journal Article

Current guidelines from EASL recommend that most patients with cirrhosis are offered surveillance for hepatocellular carcinoma (HCC), but fewer than expected patients actually receive it. The recommendation is based on observational studies and simul... Read More about We need stronger evidence for (or against) hepatocellular carcinoma surveillance.

Long term health related quality of life following colorectal cancer surgery: patient reported outcomes in a remote follow-up population (2020)
Journal Article

Background: Remote follow-up (RFU) after colorectal cancer (CRC) surgery allows delivery of surveillance tests without the need for regular outpatient clinical appointments. However, little is known about health related quality of life (HRQoL) in RFU... Read More about Long term health related quality of life following colorectal cancer surgery: patient reported outcomes in a remote follow-up population.

COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study (2020)
Journal Article

Background: A subset of patients with severe COVID-19 develop a hyperinflammatory syndrome, which might contribute to morbidity and mortality. This study explores a specific phenotype of COVID-19-associated hyperinflammation (COV-HI), and its associa... Read More about COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study.

Health related quality of life in individuals at high risk of chronic liver disease: Impact of a community diagnostic pathway (2020)
Journal Article

Objectives: There is a lack of understanding of health related quality of life (HRQoL) in chronic liver disease (CLD). With the rising prevalence of alcohol and obesity driven CLD, and the increasing ability to screen for fibrosis, it is important to... Read More about Health related quality of life in individuals at high risk of chronic liver disease: Impact of a community diagnostic pathway.

Mortality after extrahepatic gastrointestinal and abdominal wall surgery in patients with alcoholic liver disease: A systematic review and meta-analysis (2020)
Journal Article

Aims: This meta-analysis aimed to define the perioperative risk of mortality in patients with alcoholic liver disease (ALD) undergoing extrahepatic gastrointestinal surgery. Methods: Systematic searches of Embase, Medline and CENTRAL were undertak... Read More about Mortality after extrahepatic gastrointestinal and abdominal wall surgery in patients with alcoholic liver disease: A systematic review and meta-analysis.

Risk of hepatocellular carcinoma in Danish outpatients with alcohol-related cirrhosis (2020)
Journal Article

Background and aims: Accurate estimates of the risk of hepatocellular carcinoma (HCC) in patients with cirrhosis are important for clinical decisions about HCC surveillance. We described HCC risk among outpatients with alcoholic cirrhosis and contras... Read More about Risk of hepatocellular carcinoma in Danish outpatients with alcohol-related cirrhosis.

Editorial: how widespread and serious is non-alcoholic fatty liver disease in the real world? (2020)
Journal Article

Incidence, prevalence and mortality of autoimmune hepatitis in England 1997-2015. A population-based cohort study (2020)
Journal Article

© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd Background & Aims: There are few population-based studies of the incidence and mortality of autoimmune hepatitis. The burden of the disease and how it has changed over time have not... Read More about Incidence, prevalence and mortality of autoimmune hepatitis in England 1997-2015. A population-based cohort study.

Changes in the testing for and incidence of celiac disease in the UK 2005-2015: a population based cohort study (2019)
Journal Article

The diagnosis rates of coeliac disease differ substantially between countries. Intriguingly, there has been recent evidence from Olmstead County, USA and Finland that in the last 5-10 years incidence has plateaued or even declined. In most population... Read More about Changes in the testing for and incidence of celiac disease in the UK 2005-2015: a population based cohort study.

Duration and Magnitude of Postoperative Risk of Venous Thromboembolism after Cholecystectomy: A Population-Based Cohort Study (2019)
Journal Article

Background: This study aimed to identify burden and risk of VTE associated with cholecystectomy in England. Methods: An historical cohort study of cholecystectomy patients from 2001-2011 was undertaken using linked primary (Clinical Practice... Read More about Duration and Magnitude of Postoperative Risk of Venous Thromboembolism after Cholecystectomy: A Population-Based Cohort Study.

Healthcare utilisation, morbidities and alcohol use monitoring prior to alcoholic psychosis diagnosis (2018)
Journal Article

Aims: This study aimed to describe healthcare utilisation, morbidities and monitoring of alcohol use in patients prior to a diagnosis of alcoholic psychosis in order to inform the early identification of patients at risk. Method: Using linked gene... Read More about Healthcare utilisation, morbidities and alcohol use monitoring prior to alcoholic psychosis diagnosis.

Mortality in people with coeliac disease: long-term follow-up from a Scottish cohort (2018)
Journal Article

Background: Few studies have determined the very long-term mortality risks in adult and childhood-diagnosed coeliac disease. Objective: We quantified mortality risks in coeliac disease and determined whether age at diagnosis, or time following di... Read More about Mortality in people with coeliac disease: long-term follow-up from a Scottish cohort.

Reply to: “Hip fracture risk in patients with alcoholic cirrhosis: Do comorbidities and complications matter?” (2018)
Journal Article

Changing autonomy in operative experience through UK general surgery training: a national cohort study (2018)
Journal Article

Objectives:To determine the operative experience of UK general surgery trainees and assess the changing procedural supervision and acquisition of competency assessments through the course of training. Background Summary Data: Competency assessment... Read More about Changing autonomy in operative experience through UK general surgery training: a national cohort study.

Time out of general surgery specialty training in the UK: a national database study (2018)
Journal Article

Objective General surgery specialty training in the United Kingdom takes 6 years and allows trainees to take time out of training. Studies from the United States have highlighted an increasing trend for taking time out of surgical training for res... Read More about Time out of general surgery specialty training in the UK: a national database study.

Injury among children and young people with and without attention deficit-hyperactivity disorder in the community: the risk of fractures, thermal injuries and poisonings (2018)
Journal Article

Background: Injuries commonly cause morbidity and mortality in children and young people (CYP). Attention deficit-hyperactivity disorder (ADHD) is the commonest neurobehavioural disorder in CYP and is associated with increased injury risk. However, l... Read More about Injury among children and young people with and without attention deficit-hyperactivity disorder in the community: the risk of fractures, thermal injuries and poisonings.

Hip fracture risk in patients with alcoholic cirrhosis: a population-based study using English and Danish data (2018)
Journal Article

© 2018 European Association for the Study of the Liver Background & Aims: Cirrhosis, the prevalence of which is increasing, is a risk factor for osteoporosis and fractures. However, little is known of the actual risk of hip fractures in patients with... Read More about Hip fracture risk in patients with alcoholic cirrhosis: a population-based study using English and Danish data.

Attention-deficit/hyperactivity disorder: variation by socio-economic deprivation (2018)
Journal Article

Background: In England, there is a discrepancy between the prevalence of Attention-deficit/hyperactivity disorder (ADHD) ascertained from medical records and community surveys. There is also a lack of data on variation in recorded prevalence by depri... Read More about Attention-deficit/hyperactivity disorder: variation by socio-economic deprivation.

A validation study of the CirCom comorbidity score in an English cirrhosis population using the Clinical Practice Research Datalink (2018)
Journal Article

Purpose: The CirCom score has been developed from Danish data as a specific measure of comorbidity for cirrhosis to predict all-cause mortality. We compared its performance with the Charlson Comorbidity Index (CCI) in an English cirrhosis population.... Read More about A validation study of the CirCom comorbidity score in an English cirrhosis population using the Clinical Practice Research Datalink.