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All Outputs (36)

Multifunctional Bioinstructive 3D Architectures to Modulate Cellular Behavior (2019)
Journal Article
Vaithilingam, J., Sanjuan‐Alberte, P., Campora, S., Rance, G. A., Jiang, L., Thorpe, J., …Rawson, F. J. (2019). Multifunctional Bioinstructive 3D Architectures to Modulate Cellular Behavior. Advanced Functional Materials, 29(38), Article 1902016. https://doi.org/10.1002/adfm.201902016

Biological structures control cell behavior via physical, chemical, electrical, and mechanical cues. Approaches that allow us to build devices that mimic these cues in a combinatorial way are lacking due to there being no suitable instructive materia... Read More about Multifunctional Bioinstructive 3D Architectures to Modulate Cellular Behavior.

Mechanistic insight into heterogeneity of trans-plasma membrane electron transport in cancer cell types (2019)
Journal Article
Sherman, H. G., Jovanovic, C., Abuawad, A., Kim, D., Collins, H., Dixon, J. E., …Rawson, F. J. (2019). Mechanistic insight into heterogeneity of trans-plasma membrane electron transport in cancer cell types. BBA - Bioenergetics, 1860(8), 628-639. https://doi.org/10.1016/j.bbabio.2019.06.012

Trans-plasma membrane electron transfer (tMPET) is a process by which reducing equivalents, either electrons or reductants like ascorbic acid, are exported to the extracellular environment by the cell. TPMET is involved in a number of physiological p... Read More about Mechanistic insight into heterogeneity of trans-plasma membrane electron transport in cancer cell types.

Remotely controlled in situ growth of silver microwires forming bioelectronic interfaces (2019)
Journal Article
Sanjuan-Alberte, P., Saleh, E., Shaw, A. J., Lacalendola, N., Willmott, G., Vaithilingam, J., …Rawson, F. J. (2019). Remotely controlled in situ growth of silver microwires forming bioelectronic interfaces. ACS Applied Materials and Interfaces, 11(9), 8928-8936. https://doi.org/10.1021/acsami.8b22075

There is a pressing need to advance our ability to construct three-dimensional (3D) functional bioelectronic interfaces. Additionally, to ease the transition to building cellular electronic systems, a remote approach to merge electrical components wi... Read More about Remotely controlled in situ growth of silver microwires forming bioelectronic interfaces.

Reversible, High-Affinity Surface Capturing of Proteins Directed by Supramolecular Assembly (2019)
Journal Article
Di Palma, G., Kotowska, A. M., Hart, L. R., Scurr, D. J., Rawson, F. J., Tommasone, S., & Mendes, P. M. (2019). Reversible, High-Affinity Surface Capturing of Proteins Directed by Supramolecular Assembly. ACS Applied Materials and Interfaces, 11(9), 8937-8944. https://doi.org/10.1021/acsami.9b00927

The ability to design surfaces with reversible, high-affinity protein binding sites represents a significant step forward in the advancement of analytical methods for diverse biochemical and biomedical applications. Herein, we report a dynamic supram... Read More about Reversible, High-Affinity Surface Capturing of Proteins Directed by Supramolecular Assembly.

Mammalian cell-driven polymerisation of pyrrole (2018)
Journal Article
Sherman, H. G., Jain, A., Stolnik, S., Alexander, C., Rawson, F. J., & Hicks, J. (2018). Mammalian cell-driven polymerisation of pyrrole. ChemBioChem, 20(8), 1008-1013. https://doi.org/10.1002/cbic.201800630

A model cancer cell line was used to initiate polymerisation of pyrrole to form the conducting material polypyrrole. The polymerisation was shown to occur via cytosolic exudates rather than via membrane redox sites which normally control the oxidatio... Read More about Mammalian cell-driven polymerisation of pyrrole.

New perspectives on iron uptake in eukaryotes (2018)
Journal Article
Sherman, H. G., Jovanovic, C., Stolnik, S., Baronian, K., Downard, A. J., & Rawson, F. J. (2018). New perspectives on iron uptake in eukaryotes. Frontiers in Molecular Biosciences, 5(NOV), Article 97. https://doi.org/10.3389/fmolb.2018.00097

All eukaryotic organisms require iron to function. Malfunctions within iron homeostasis have a range of physiological consequences, and can lead to the development of pathological conditions that can result in an excess of non-transferrin bound iron... Read More about New perspectives on iron uptake in eukaryotes.

Electrochemically stimulating developments in bioelectronic medicine (2018)
Journal Article
Sanjuan-Alberte, P., Alexander, M. R., Hague, R. J., & Rawson, F. J. (2018). Electrochemically stimulating developments in bioelectronic medicine. Bioelectronic Medicine, 4(1), https://doi.org/10.1186/s42234-018-0001-z

Cellular homeostasis is in part controlled by biological generated electrical activity. By interfacing biology with electronic devices this electrical activity can be modulated to actuate cellular behaviour. There are current limitations in merging e... Read More about Electrochemically stimulating developments in bioelectronic medicine.

An electrochemical system for the study of trans-plasma membrane electron transport in whole eukaryotic cells (2018)
Journal Article
Sherman, H. G., Jovanovic, C., Stolnik, S., & Rawson, F. J. (in press). An electrochemical system for the study of trans-plasma membrane electron transport in whole eukaryotic cells. Analytical Chemistry, 90(4), https://doi.org/10.1021/acs.analchem.7b04853

The development of new assays to study trans-plasma membrane electron transport (tPMET) in eukaryotic systems is paramount for a number reasons, which include the further understanding of the underlying biology which can then potentially be applied t... Read More about An electrochemical system for the study of trans-plasma membrane electron transport in whole eukaryotic cells.

Tailoring the electrochemical properties of carbon nanotube modified indium tin oxide via in situ grafting of aryl diazonium (2017)
Journal Article
Wong, Z. Y., Scurr, D. J., Silman, N., Jackson, S. K., Mendes, P. M., Aylott, J. W., …Hicks, J. (2017). Tailoring the electrochemical properties of carbon nanotube modified indium tin oxide via in situ grafting of aryl diazonium. Langmuir, 33(20), 4924-4933. https://doi.org/10.1021/acs.langmuir.7b00494

Our ability to tailor the electronic properties of surfaces by nanomodification is paramount for various applications, including development of sensing, fuel cell, and solar technologies. Moreover, in order to improve the rational design of conductin... Read More about Tailoring the electrochemical properties of carbon nanotube modified indium tin oxide via in situ grafting of aryl diazonium.

Electrochemical communication with the inside of cells using micro-patterned vertical carbon nanofibre electrodes (2016)
Journal Article
Rawson, F. J., Cole, M., Aylott, J. W., Milne, W., Collins, C., Jackson, S. K., …Hicks, J. (in press). Electrochemical communication with the inside of cells using micro-patterned vertical carbon nanofibre electrodes. Scientific Reports, 6(37672), https://doi.org/10.1038/srep37672

With the rapidly increasing demands for ultrasensitive biodetection, the design and applications of new nano-scale materials for development of sensors based on optical and electrochemical transducers have attracted substantial interest. In particula... Read More about Electrochemical communication with the inside of cells using micro-patterned vertical carbon nanofibre electrodes.

Fast, ultrasensitive detection of reactive oxygen species using a carbon nanotube based-electrocatalytic intracellular sensor (2015)
Journal Article
Rawson, F. J., Dodd, N., Abate, W., Garrett, D. J., Yip, N.-C., Fejer, G., …Hicks, J. (2015). Fast, ultrasensitive detection of reactive oxygen species using a carbon nanotube based-electrocatalytic intracellular sensor. ACS Applied Materials and Interfaces, 7(42), https://doi.org/10.1021/acsami.5b06493

Herein, we report a highly sensitive electrocatalytic sensor-cell construct that can electrochemically communicate with the internal environment of immune cells (e.g., macrophages) via the selective monitoring of a particular reactive oxygen species... Read More about Fast, ultrasensitive detection of reactive oxygen species using a carbon nanotube based-electrocatalytic intracellular sensor.

Electronic communication of cells with a surface mediated by boronic acid saccharide interactions (2015)
Journal Article
Stephenson-Brown, A., Yong, S., Mansor, M. H., Hussein, Z., Yip, N.-C., Mendes, P. M., …Rawson, F. J. (2015). Electronic communication of cells with a surface mediated by boronic acid saccharide interactions. Chemical Communications, 51(97), https://doi.org/10.1039/C5CC04311E

The fabrication of a molecularly tailored surface functionalised with a saccharide binding motif, a phenyl boronic acid derivative is reported.The functionalised surface facilitated the transfer of electrons, via unique electronic interactions mediat... Read More about Electronic communication of cells with a surface mediated by boronic acid saccharide interactions.

New insights into electrocatalysis based on plasmon resonance for the real-time monitoring of catalytic events on single gold nanorods (2014)
Journal Article

Gold nanoparticles (GNPs) have been widely applied in industrial catalysis and electrocatalysis. Owing to their wide variety of shapes, sizes, and compositions, a range of different catalytic properties is possible. Thus, it is important to monitor c... Read More about New insights into electrocatalysis based on plasmon resonance for the real-time monitoring of catalytic events on single gold nanorods.