Remotely controlled in situ growth of silver microwires forming bioelectronic interfaces

Sanjuan-Alberte, Paola; Saleh, Ehab; Shaw, Andie J.; Lacalendola, Nicola; Willmott, Geoff; Vaithilingam, Jayasheelan; Alexander, Morgan R.; Hague, Richard J. M.; Rawson, Frankie J.

Abstract

There is a pressing need to advance our ability to construct three-dimensional (3D) functional bioelectronic interfaces. Additionally, to ease the transition to building cellular electronic systems, a remote approach to merge electrical components with biology is desirable. By combining 3D digital inkjet printing with bipolar electrochemistry, we remotely control and fabricate conductive wires, forming a first of its kind contactless bionic manufacturing procedure. It enables controlled fabrication of conductive wires in a three-dimensional configuration. Moreover, we demonstrate that this technology could be used to grow and interface conductive conduits in situ with mammalian cells, offering a new strategy to engineering bioelectronic interfaces. This represents a step change in the production of functional complex circuitry and considerably increases the manufacturing capabilities of merging cells with electronics. This approach provides a platform to construct bioelectronics in situ offering a potential paradigm shift in the methods for building bioelectronics with potential applications in biosensing and bioelectronic medicine.

Citation

Sanjuan-Alberte, P., Saleh, E., Shaw, A. J., Lacalendola, N., Willmott, G., Vaithilingam, J., Alexander, M. R., Hague, R. J. M., & Rawson, F. J. (2019). Remotely controlled in situ growth of silver microwires forming bioelectronic interfaces. ACS Applied Materials and Interfaces, 11(9), 8928-8936. https://doi.org/10.1021/acsami.8b22075

• Journal Article Type: Article
• Acceptance Date: Feb 8, 2019
• Online Publication Date: Feb 8, 2019
• Publication Date: Feb 8, 2019
• Deposit Date: Mar 1, 2019
• Publicly Available Date: Apr 3, 2019
• Journal: ACS Applied Materials & Interfaces
• Print ISSN: 1944-8244
• Electronic ISSN: 1944-8252
• Publisher: American Chemical Society
• Peer Reviewed: Peer Reviewed
• Volume: 11
• Issue: 9
• Pages: 8928-8936
• DOI: https://doi.org/10.1021/acsami.8b22075
• Keywords: bioelectronic interfaces, microwire growth, bipolar electrochemistry, inkjet printing, bionic manufacturing
• Public URL: https://nottingham-repository.worktribe.com/output/1595940
• Publisher URL: https://pubs.acs.org/doi/10.1021/acsami.8b22075
• Contract Date: Mar 1, 2019