Electronic communication of cells with a surface mediated by boronic acid saccharide interactions

Stephenson-Brown, Alex; Yong, Sue; Mansor, Muhammad H.; Hussein, Zarrar; Yip, Nga-Chi; Mendes, Paula M.; Fossey, John S.; Rawson, Frankie J.

Abstract

The fabrication of a molecularly tailored surface functionalised with a saccharide binding motif, a phenyl boronic acid derivative is reported.The functionalised surface facilitated the transfer of electrons, via unique electronic interactions mediated by the presence of the boronic acid, from a macrophage cell line. This is the first example of eukaryotic cellular-electrical communication mediated by the binding of cells via their cell–surface saccharide units.

Citation

Stephenson-Brown, A., Yong, S., Mansor, M. H., Hussein, Z., Yip, N.-C., Mendes, P. M., Fossey, J. S., & Rawson, F. J. (2015). Electronic communication of cells with a surface mediated by boronic acid saccharide interactions. Chemical Communications, 51(97), https://doi.org/10.1039/C5CC04311E

• Journal Article Type: Article
• Acceptance Date: Sep 10, 2015
• Online Publication Date: Sep 15, 2015
• Publication Date: Dec 18, 2015
• Deposit Date: Sep 29, 2015
• Publicly Available Date: Sep 29, 2015
• Journal: Chemical Communications
• Print ISSN: 1359-7345
• Electronic ISSN: 1364-548X
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 51
• Issue: 97
• DOI: https://doi.org/10.1039/C5CC04311E
• Keywords: bioelectrochemistry, boronic acid, cell electrochemistry,
• Public URL: https://nottingham-repository.worktribe.com/output/768998
• Publisher URL: http://pubs.rsc.org/en/Content/ArticleLanding/2015/CC/C5CC04311E#!divAbstract
• Contract Date: Sep 29, 2015