M. Garcia
Feasibility of Flat Panel Detector CT in Perfusion Assessment of Brain Arteriovenous Malformations: Initial Clinical Experience
Garcia, M.; Okell, T.W.; Gloor, M.; Chappell, M.A.; Jezzard, P.; Bieri, O.; Byrne, J.V.
Authors
T.W. Okell
M. Gloor
Prof MICHAEL CHAPPELL MICHAEL.CHAPPELL@NOTTINGHAM.AC.UK
Professor of Biomedical Imaging
P. Jezzard
O. Bieri
J.V. Byrne
Abstract
The different results from flat panel detector CT in various pathologies have provoked some discussion. Our aim was to assess the role of flat panel detector CT in brain arteriovenous malformations, which has not yet been assessed. Five patients with brain arteriovenous malformations were studied with flat panel detector CT, DSC-MR imaging, and vessel-encoded pseudocontinuous arterial spin-labeling. In glomerular brain arteriovenous malformations, perfusion was highest next to the brain arteriovenous malformation with decreasing values with increasing distance from the lesion. An inverse tendency was observed in the proliferative brain arteriovenous malformation. Flat panel detector CT, originally thought to measure blood volume, correlated more closely with arterial spin-labeling-CBF and DSC-CBF than with DSC-CBV. We conclude that flat panel detector CT perfusion depends on the time point chosen for data collection, which is triggered too early in these patients (ie, when contrast agent appears in the superior sagittal sinus after rapid shunting through the brain arteriovenous malformation). This finding, in combination with high data variability, makes flat panel detector CT inappropriate for perfusion assessment in brain arteriovenous malformations.
Journal Article Type | Article |
---|---|
Acceptance Date | Dec 1, 2016 |
Online Publication Date | Feb 16, 2017 |
Publication Date | 2017-04 |
Deposit Date | Sep 28, 2020 |
Journal | American Journal of Neuroradiology |
Print ISSN | 0195-6108 |
Electronic ISSN | 1936-959X |
Publisher | American Society of Neuroradiology |
Peer Reviewed | Peer Reviewed |
Volume | 38 |
Issue | 4 |
Pages | 735-739 |
DOI | https://doi.org/10.3174/ajnr.a5091 |
Public URL | https://nottingham-repository.worktribe.com/output/4930925 |
Publisher URL | http://www.ajnr.org/content/38/4/735 |
You might also like
MRI assessment of cerebral perfusion in clinical trials
(2023)
Journal Article
Amide proton transfer imaging in stroke
(2022)
Journal Article
Downloadable Citations
About Repository@Nottingham
Administrator e-mail: discovery-access-systems@nottingham.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search