Outputs (2545)

The role of CAPG in molecular communication between the embryo and the uterine endometrium: Is its function conserved in species with different implantation strategies? (2020)
Journal Article
Tinning, H., Taylor, A., Wang, D., Constantinides, B., Sutton, R., Oikonomou, G., Velazquez, M. A., Thompson, P., Treumann, A., O'Connell, M. J., & Forde, N. (2020). The role of CAPG in molecular communication between the embryo and the uterine endometrium: Is its function conserved in species with different implantation strategies?. FASEB Journal, 34(8), 11015-11029. https://doi.org/10.1096/fj.202000882rr

© 2020. The Authors. The FASEB Journal published by Wiley Periodicals LLC on behalf of Federation of American Societies for Experimental Biology During the preimplantation period of pregnancy in eutherian mammals, transcriptional and proteomic change... Read More about The role of CAPG in molecular communication between the embryo and the uterine endometrium: Is its function conserved in species with different implantation strategies?.

Inkjet based 3D Printing of bespoke medical devices that resist bacterial biofilm formation (2020)
Preprint / Working Paper
He, Y., Begines, B., Luckett, J., Dubern, J.-F., Hook, A., Prina, E., Rose, F. R., Tuck, C., Hague, R., Irvine, D., Williams, P., Alexander, M. R., & Wildman, R. D. Inkjet based 3D Printing of bespoke medical devices that resist bacterial biofilm formation

We demonstrate the formulation of advanced functional 3D printing inks that prevent the formation of bacterial biofilms in vivo. Starting from polymer libraries, we show that a biofilm resistant object can be 3D printed with the potential for shape a... Read More about Inkjet based 3D Printing of bespoke medical devices that resist bacterial biofilm formation.

A novel allele of ASY3 is associated with greater meiotic stability in autotetraploid Arabidopsis lyrata (2020)
Journal Article
Seear, P. J., France, M. G., Gregory, C. L., Heavens, D., Schmickl, R., Yant, L., & Higgins, J. D. (2020). A novel allele of ASY3 is associated with greater meiotic stability in autotetraploid Arabidopsis lyrata. PLoS Genetics, 16(7), Article e1008900. https://doi.org/10.1371/journal.pgen.1008900

In this study we performed a genotype-phenotype association analysis of meiotic stability in 10 autotetraploid Arabidopsis lyrata and A. lyrata/A. arenosa hybrid populations collected from the Wachau region and East Austrian Forealps. The aim was to... Read More about A novel allele of ASY3 is associated with greater meiotic stability in autotetraploid Arabidopsis lyrata.

Prior exposure to long-day photoperiods alters immune responses and increases susceptibility to parasitic infection in stickleback (2020)
Journal Article
Whiting, J. R., Mahmud, M. A., Bradley, J. E., & MacColl, A. D. (2020). Prior exposure to long-day photoperiods alters immune responses and increases susceptibility to parasitic infection in stickleback. Proceedings of the Royal Society B: Biological Sciences, 287(1930), https://doi.org/10.1098/rspb.2020.1017

Seasonal disease and parasitic infection are common across organisms, including humans, and there is increasing evidence for intrinsic seasonal variation in immune systems. Changes are orchestrated through organisms' physiological clocks using cues s... Read More about Prior exposure to long-day photoperiods alters immune responses and increases susceptibility to parasitic infection in stickleback.

A next generation vaccine against human rabies based on a single dose of a chimpanzee adenovirus vector serotype C (2020)
Journal Article
Napolitano, F., Merone, R., Abbate, A., Ammendola, V., Horncastle, E., Lanzaro, F., Esposito, M., Contino, A. M., Sbrocchi, R., Sommella, A., Duncan, J. D., Hinds, J., Urbanowicz, R. A., Lahm, A., Colloca, S., Folgori, A., Ball, J. K., Nicosia, A., Wizel, B., Capone, S., & Vitelli, A. (2020). A next generation vaccine against human rabies based on a single dose of a chimpanzee adenovirus vector serotype C. PLoS Neglected Tropical Diseases, 14(7), Article e0008459. https://doi.org/10.1371/journal.pntd.0008459

Rabies, caused by RNA viruses in the Genus Lyssavirus, is the most fatal of all infectious diseases. This neglected zoonosis remains a major public health problem in developing countries, causing the death of an estimated 25,000-159,000 people each y... Read More about A next generation vaccine against human rabies based on a single dose of a chimpanzee adenovirus vector serotype C.

Monitoring Allosteric Interactions with CXCR4 Using NanoBiT Conjugated Nanobodies (2020)
Journal Article
Soave, M., Heukers, R., Kellam, B., Woolard, J., Smit, M. J., Briddon, S. J., & Hill, S. J. (2020). Monitoring Allosteric Interactions with CXCR4 Using NanoBiT Conjugated Nanobodies. Cell Chemical Biology, 27, 1-12. https://doi.org/10.1016/j.chembiol.2020.06.006

© 2020 The Authors Camelid single-domain antibody fragments (nanobodies) offer the specificity of an antibody in a single 15-kDa immunoglobulin domain. Their small size allows for easy genetic manipulation of the nanobody sequence to incorporate prot... Read More about Monitoring Allosteric Interactions with CXCR4 Using NanoBiT Conjugated Nanobodies.

Achieving Microparticles with Cell-Instructive Surface Chemistry by Using Tunable Co-Polymer Surfactants (2020)
Journal Article
Dundas, A. A., Cuzzucoli Crucitti, V., Haas, S., Dubern, J., Latif, A., Romero, M., Sanni, O., Ghaemmaghami, A. M., Williams, P., Alexander, M. R., Wildman, R., & Irvine, D. J. (2020). Achieving Microparticles with Cell-Instructive Surface Chemistry by Using Tunable Co-Polymer Surfactants. Advanced Functional Materials, 30(36), Article 2001821. https://doi.org/10.1002/adfm.202001821

© 2020 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim A flow-focusing microfluidic device is used to produce functionalized monodisperse polymer particles with surface chemistries designed to control bacterial biofilm formatio... Read More about Achieving Microparticles with Cell-Instructive Surface Chemistry by Using Tunable Co-Polymer Surfactants.

Targeted genotype analyses of GWAS-derived lean body mass and handgrip strength-associated single nucleotide polymorphisms in elite masters athletes (2020)
Journal Article
Crossland, H., Piasecki, J., McCormick, D., Phillips, B. E., Wilkinson, D. J., Smith, K., McPhee, J. S., Piasecki, M., & Atherton, P. J. (2020). Targeted genotype analyses of GWAS-derived lean body mass and handgrip strength-associated single nucleotide polymorphisms in elite masters athletes. AJP - Regulatory, Integrative and Comparative Physiology, 319(2), R184-R194. https://doi.org/10.1152/ajpregu.00110.2020

Recent large genome-wide association studies (GWAS) have independently identified a set of genetic loci associated with lean body mass (LBM) and handgrip strength (HGS). Evaluation of these candidate single nucleotide polymorphisms (SNPs) may be usef... Read More about Targeted genotype analyses of GWAS-derived lean body mass and handgrip strength-associated single nucleotide polymorphisms in elite masters athletes.

The Added Value of Longitudinal Imaging for Preclinical In Vivo Efficacy Testing of Therapeutic Compounds against Cerebral Cryptococcosis (2020)
Journal Article
Vanherp, L., Poelmans, J., Hillen, A., Janbon, G., Brock, M., Lagrou, K., Velde, G. V., & Himmelreich, U. (2020). The Added Value of Longitudinal Imaging for Preclinical In Vivo Efficacy Testing of Therapeutic Compounds against Cerebral Cryptococcosis. Antimicrobial Agents and Chemotherapy, 64(7), https://doi.org/10.1128/aac.00070-20

© 2020 American Society for Microbiology. All rights reserved. Brain infections with Cryptococcus neoformans are associated with significant morbidity and mortality. Cryptococcosis typically presents as meningoencephalitis or fungal mass lesions call... Read More about The Added Value of Longitudinal Imaging for Preclinical In Vivo Efficacy Testing of Therapeutic Compounds against Cerebral Cryptococcosis.

A divergent cyclin/cyclin-dependent kinase complex controls the atypical replication of a malaria parasite during gametogony and transmission (2020)
Journal Article
Balestra, A. C., Zeeshan, M., Rea, E., Pasquarello, C., Brusini, L., Mourier, T., Subudhi, A. K., Klages, N., Arboit, P., Pandey, R., Brady, D., Vaughan, S., Holder, A. A., Pain, A., Ferguson, D. J., Hainard, A., Tewari, R., & Brochet, M. (2020). A divergent cyclin/cyclin-dependent kinase complex controls the atypical replication of a malaria parasite during gametogony and transmission. eLife, 9, Article e56474. https://doi.org/10.7554/eLife.56474

© 2020, Balestra et al. Cell cycle transitions are generally triggered by variation in the activity of cyclin-dependent kinases (CDKs) bound to cyclins. Malaria-causing parasites have a life cycle with unique cell-division cycles, and a repertoire of... Read More about A divergent cyclin/cyclin-dependent kinase complex controls the atypical replication of a malaria parasite during gametogony and transmission.