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Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1 (2024)
Journal Article
Coleman, D. J., Keane, P., Chin, P. S., Ames, L., Kellaway, S., Blair, H., …Bonifer, C. (2024). Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1. iScience, 27(4), Article 109576. https://doi.org/10.1016/j.isci.2024.109576

AML is characterized by mutations in genes associated with growth regulation such as internal tandem duplications (ITD) in the receptor kinase FLT3. Inhibitors targeting FLT3 (FLT3i) are being used to treat patients with FLT3-ITD+ but most relapse an... Read More about Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1.

Motherhood, Human Trafficking, and Asylum Seeking: The Experiences and Needs of Survivor Mothers in Birthing and Postnatal Care (2024)
Journal Article
Bosatta, L., Crespi De Valldaura, M., Bales, K., Spiby, H., & Bhriain, L. N. (2024). Motherhood, Human Trafficking, and Asylum Seeking: The Experiences and Needs of Survivor Mothers in Birthing and Postnatal Care. Societies, 14(5), Article 69. https://doi.org/10.3390/soc14050069

This article aims to illuminate the little-studied phenomenon of asylum-seeking child-bearing women in the UK, survivors of violence and human trafficking. This is a significant issue in terms of the proportion of women affected and the paucity of ca... Read More about Motherhood, Human Trafficking, and Asylum Seeking: The Experiences and Needs of Survivor Mothers in Birthing and Postnatal Care.

Performance improvement of the automotive thermoelectric generator by extending the hot side area of the heat exchanger through heat pipes (2024)
Journal Article
Luo, D., Yang, S., Yan, Y., Cao, J., & Cao, B. (2024). Performance improvement of the automotive thermoelectric generator by extending the hot side area of the heat exchanger through heat pipes. Energy Conversion and Management, 310, Article 118472. https://doi.org/10.1016/j.enconman.2024.118472

In pursuit of enhancing the utilization of exhaust heat in the automotive thermoelectric generator (ATEG), this study introduces a novel heat exchanger with integrated heat pipes to extend the effective hot-side surface area. Meanwhile, a numerical m... Read More about Performance improvement of the automotive thermoelectric generator by extending the hot side area of the heat exchanger through heat pipes.

Ambient air quality monitoring for healthcare settings (2023)
Report
Baldo, C., Cowell, N., Rooney, D. J., Bloss, W. J., & Bartington, S. (2023). Ambient air quality monitoring for healthcare settings. WM-AIR

The WM-Air team has released a new guidance document, Ambient air quality monitoring for healthcare settings¸ with the aim of supporting the development and understanding of air quality monitoring within healthcare settings. Building on research expe... Read More about Ambient air quality monitoring for healthcare settings.

Exploring the dynamic characteristics of thermoelectric generator under fluctuations of exhaust heat (2024)
Journal Article
Luo, D., Yan, Y., Chen, W. H., & Cao, B. (2024). Exploring the dynamic characteristics of thermoelectric generator under fluctuations of exhaust heat. International Journal of Heat and Mass Transfer, 222, Article 125151. https://doi.org/10.1016/j.ijheatmasstransfer.2023.125151

The thermoelectric generator is a potential candidate to recover waste heat from exhaust gas. Regarding the fluctuations of exhaust heat in practical situations, this paper adopts a transient fluid-thermal-electric multiphysics model to investigate t... Read More about Exploring the dynamic characteristics of thermoelectric generator under fluctuations of exhaust heat.