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Communication, Collaboration, and Coordination in a Co-located Shared Augmented Reality Game: Perspectives From Deaf and Hard of Hearing People (2024)
Conference Proceeding
Luna, S. M., Xu, J., Papangelis, K., Tigwell, G. W., LaLone, N., Saker, M., …Wang, Y. (2024). Communication, Collaboration, and Coordination in a Co-located Shared Augmented Reality Game: Perspectives From Deaf and Hard of Hearing People. In Proceedings of the CHI Conference on Human Factors in Computing Systems (CHI ’24), May 11–16, 2024, Honolulu, HI, USA. https://doi.org/10.1145/3613904.3642953

Co-located collaborative shared augmented reality (CS-AR) environments have gained considerable research attention, mainly focusing on design, implementation, accuracy, and usability. Yet, a gap persists in our understanding regarding the accessibili... Read More about Communication, Collaboration, and Coordination in a Co-located Shared Augmented Reality Game: Perspectives From Deaf and Hard of Hearing People.

Menace or Medicine: What to do with Nettles? (2024)
Book Chapter
Connelly, E., & Lee, C. (in press). Menace or Medicine: What to do with Nettles?. In Medicine in the Medieval North Atlantic World: Vernacular Texts and Traditions. Brepols Publishers

This paper answers Strabo’s question of 'what to do with nettles' by discussing the worth of nettles in select research outcomes from a project which examined the potential medicinal qualities of nettles (restricted to Urtica dioica) inspired by ear... Read More about Menace or Medicine: What to do with Nettles?.

Group concept mapping to facilitate participatory design of the web-based Pain-at-Work Toolkit (2024)
Conference Proceeding
Blake, H., Greaves, S., Abbott-Fleming, V., & Somerset, S. (2024). Group concept mapping to facilitate participatory design of the web-based Pain-at-Work Toolkit. . https://doi.org/10.21125/inted.2024.1530

Concept mapping is increasingly being used as an approach to enhance the development of evidence-based public health interventions. In a prior collaborative-participatory study, Agile methodology was used to co-create the web-based Pain-at-Work (PAW)... Read More about Group concept mapping to facilitate participatory design of the web-based Pain-at-Work Toolkit.

Delivering web-based workforce training interventions: the WWHIDE framework and key considerations for health research (2024)
Conference Proceeding
Blake, H., Chaplin, W., Hassard, J., & Thomson, L. (2024). Delivering web-based workforce training interventions: the WWHIDE framework and key considerations for health research. In INTED2024 Proceedings: 18th International Technology, Education and Development Conference Valencia, Spain. 4-6 March, 2024. https://doi.org/10.21125/inted.2024.1529

The workplace is an important setting for raising awareness of public health issues and delivering interventions to promote health and wellbeing of working-age adults. The role of employers in supporting the physical and mental health of their employ... Read More about Delivering web-based workforce training interventions: the WWHIDE framework and key considerations for health research.

Assessing the prevalence and potential drivers of food insecurity and the relationship with mental wellbeing in UK university students: A cross-sectional study (2024)
Journal Article
Aldubaybi, A. A., Coneyworth, L. J., & Jethwa, P. H. (2024). Assessing the prevalence and potential drivers of food insecurity and the relationship with mental wellbeing in UK university students: A cross-sectional study. Nutrition Bulletin, 49(1), 96-107. https://doi.org/10.1111/nbu.12662

Food insecurity (FI) among university students in the United States has been associated with poor mental wellbeing, but very little is known about the relationship between FI and mental wellbeing in the UK university population. Here we examined the... Read More about Assessing the prevalence and potential drivers of food insecurity and the relationship with mental wellbeing in UK university students: A cross-sectional study.

Realist Evaluation Comparison of Dementia-Friendly Communities in England and the Netherlands (2024)
Journal Article
Chadborn, N. H., Thijssen, M., Logan, P., Radford, K., & Graff, M. (2024). Realist Evaluation Comparison of Dementia-Friendly Communities in England and the Netherlands. Health and Social Care in the Community, 2024, Article 5576029. https://doi.org/10.1155/2024/5576029

Introduction. Dementia-friendly communities coordinate activities and events which offer social inclusion and participation of people with dementia. Initiatives can include memory cafés, sports, and tourist and heritage visits. This study explored ho... Read More about Realist Evaluation Comparison of Dementia-Friendly Communities in England and the Netherlands.

Disruption of Epithelial Barriers for Molecular Delivery Enhancement or Extraction of Extracellular Fluids (2024)
Patent
Webb, K., Moradi, E., & Foss, A. (2024). Disruption of Epithelial Barriers for Molecular Delivery Enhancement or Extraction of Extracellular Fluids. WO2024009101A1. UK

The invention provides a method of delivering a payload molecule across an epithelial tissue barrier, the method comprising: applying the payload molecule to the epithelial tissue barrier, and additionally applying an agent to the epithelial tissue b... Read More about Disruption of Epithelial Barriers for Molecular Delivery Enhancement or Extraction of Extracellular Fluids.

It was the best of times; it was the worst of times - Health and wellbeing in Nottingham during the 2022 heatwave (2024)
Report
Ogunbode, C., Cooper, E., Prosser, A., Kirkcaldy, H., & Hui, A. (2024). It was the best of times; it was the worst of times - Health and wellbeing in Nottingham during the 2022 heatwave. Nottingham: Nottingham City Council

Previous research provided indications of areas in Nottingham that face higher risks during hot periods based on social and geographical data, but there was little insight into lived experiences of dealing with heat among Nottingham communities. We d... Read More about It was the best of times; it was the worst of times - Health and wellbeing in Nottingham during the 2022 heatwave.

A Multimodal Linguistic Analysis of Gaze and Active Listenership in Emergency Department Team Interactions (2023)
Book Chapter
Atkins, S., & Chałupnik, M. (2023). A Multimodal Linguistic Analysis of Gaze and Active Listenership in Emergency Department Team Interactions. In K. Tsuchiya, F. Coffey, & K. Nakamura (Eds.), Multimodal Approaches to Healthcare Communication Research: Visualizing Interactions for Resilient Healthcare in the UK and Japan (47–64). London: Bloomsbury Academic. https://doi.org/10.5040/9781350298507.ch-004

Empirical Quantification of Predictive Uncertainty Due to Model Discrepancy by Training with an Ensemble of Experimental Designs: An Application to Ion Channel Kinetics (2023)
Journal Article
Shuttleworth, J. G., Lei, C. L., Whittaker, D. G., Windley, M. J., Hill, A. P., Preston, S. P., & Mirams, G. R. (2024). Empirical Quantification of Predictive Uncertainty Due to Model Discrepancy by Training with an Ensemble of Experimental Designs: An Application to Ion Channel Kinetics. Bulletin of Mathematical Biology, 86(1), Article 2. https://doi.org/10.1007/s11538-023-01224-6

When using mathematical models to make quantitative predictions for clinical or industrial use, it is important that predictions come with a reliable estimate of their accuracy (uncertainty quantification). Because models of complex biological system... Read More about Empirical Quantification of Predictive Uncertainty Due to Model Discrepancy by Training with an Ensemble of Experimental Designs: An Application to Ion Channel Kinetics.

The impact of uncertainty in hERG binding mechanism on in silico predictions of drug-induced proarrhythmic risk (2023)
Journal Article
Lei, C. L., Whittaker, D. G., & Mirams, G. R. (2024). The impact of uncertainty in hERG binding mechanism on in silico predictions of drug-induced proarrhythmic risk. British Journal of Pharmacology, 181(7), 987-1004. https://doi.org/10.1111/bph.16250

Background and Purpose Drug-induced reduction of the rapid delayed rectifier potassium current carried by the human Ether-à-go-go-Related Gene (hERG) channel is associated with increased risk of arrhythmias. Recent updates to drug safety regulatory... Read More about The impact of uncertainty in hERG binding mechanism on in silico predictions of drug-induced proarrhythmic risk.

Elevated PLAUR is observed in the airway epithelium of asthma patients and blocking improves barrier integrity (2023)
Journal Article
Portelli, M. A., Bhaker, S., Pang, V., Bates, D. O., Johnson, S. R., Mazar, A. P., …Sayers, I. (2023). Elevated PLAUR is observed in the airway epithelium of asthma patients and blocking improves barrier integrity. Clinical and Translational Allergy, 13(10), Article e12293. https://doi.org/10.1002/clt2.12293

AbstractBackgroundExpression of the urokinase plasminogen activator receptor (uPAR) is elevated in the airway epithelium in asthma; however, the contribution of uPAR to asthma pathogenesis and scope for therapeutic targeting remains unknown.Objective... Read More about Elevated PLAUR is observed in the airway epithelium of asthma patients and blocking improves barrier integrity.

Controlled release of MT-1207 using a novel gastroretentive bilayer system comprised of hydrophilic and hydrophobic polymers (2023)
Journal Article
Vrettos, N., Wang, P., Wang, Y., Roberts, C. J., Xu, J., Yao, H., & Zhu, Z. (2023). Controlled release of MT-1207 using a novel gastroretentive bilayer system comprised of hydrophilic and hydrophobic polymers. Pharmaceutical Development and Technology, 28(8), 724-742. https://doi.org/10.1080/10837450.2023.2238822

In the present study, novel gastroretentive bilayer tablets were developed that are promising for the once-a-day oral delivery of the drug candidate MT-1207. The gastroretentive layer consisted of a combination of hydrophilic and hydrophobic polymers... Read More about Controlled release of MT-1207 using a novel gastroretentive bilayer system comprised of hydrophilic and hydrophobic polymers.

Mental Health Promotion, Psychological Therapies and Young People's Mental Health (2023)
Book Chapter
Horrocks, M. (2023). Mental Health Promotion, Psychological Therapies and Young People's Mental Health. In The essential guide to public health and health promotion. (Second edition). Routledge

The mental health and well-being of young people is a key consideration for modern societies, and this chapter will focus on mental health promotion for young people. In particular, this chapter will explore the application of Cognitive Behavioural p... Read More about Mental Health Promotion, Psychological Therapies and Young People's Mental Health.

Computational Cardiac Safety Testing (2023)
Book Chapter
Mirams, G. R. (2023). Computational Cardiac Safety Testing. In F. J. Hock, M. R. Gralinski, & M. K. Pugsley (Eds.), Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays (1-33). Springer. https://doi.org/10.1007/978-3-030-73317-9_137-1

In recent years, computational cardiac electrophysiology simulations using mathematical models have begun to be used in industrial and regulatory assessment of the proarrhythmic risk of candidate drug compounds. The aim of this chapter is to equip th... Read More about Computational Cardiac Safety Testing.

The association between prescription drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a UK population-based study (2023)
Working Paper
Swiderski, M., Vinogradova, Y., Knaggs, R., Harman, K., Harwood, R., Prasad, V., …Gran, S. (0000). The association between prescription drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a UK population-based study

Introduction Bullous pemphigoid (BP) is a serious skin disease that results in large painful blisters developing over the body and occurs most commonly in older people (over 70 years). Despite several comorbidities such as stroke and a threefold inc... Read More about The association between prescription drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a UK population-based study.

Conformational analysis and interaction of the Staphylococcus aureus transmembrane peptidase AgrB with its AgrD propeptide substrate (2023)
Journal Article
Bardelang, P., Murray, E. J., Blower, I., Zandomeneghi, S., Goode, A., Hussain, R., …Bonev, B. B. (2023). Conformational analysis and interaction of the Staphylococcus aureus transmembrane peptidase AgrB with its AgrD propeptide substrate. Frontiers in Chemistry, 11, Article 1113885. https://doi.org/10.3389/fchem.2023.1113885

Virulence gene expression in the human pathogen, S. aureus is regulated by the agr (accessory gene regulator) quorum sensing (QS) system which is conserved in diverse Gram-positive bacteria. The agr QS signal molecule is an autoinducing peptide (AIP)... Read More about Conformational analysis and interaction of the Staphylococcus aureus transmembrane peptidase AgrB with its AgrD propeptide substrate.

‘We went from understanding, to disappointment, resentment and often grief all in the space of 6 months’ A qualitative study of the stories of family carers of care home residents during COVID-19 pandemic in 2020 (2023)
Working Paper
Hinsliff-Smith, K., Griffiths, S., Padley, W., De Vries, K., & Brown, J. (0000). ‘We went from understanding, to disappointment, resentment and often grief all in the space of 6 months’ A qualitative study of the stories of family carers of care home residents during COVID-19 pandemic in 2020

When the WHO announced a global pandemic in response to COVID-19, individual countries reacted in a similar way with care homes closing their doors to visits, including visits from family members. The UK was no different, initially they closed to pro... Read More about ‘We went from understanding, to disappointment, resentment and often grief all in the space of 6 months’ A qualitative study of the stories of family carers of care home residents during COVID-19 pandemic in 2020.