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Knowns and unknowns of TiLV-associated neuronal disease (2024)
Journal Article
Kembou-Ringert, J. E., Hotio, F. N., Steinhagen, D., Thompson, K. D., Surachetpong, W., Rakus, K., …Adamek, M. (in press). Knowns and unknowns of TiLV-associated neuronal disease. Virulence, 15(1), Article 2329568. https://doi.org/10.1080/21505594.2024.2329568

Tilapia Lake Virus (TiLV) is associated with pathological changes in the brain of infected fish, but the mechanisms driving the virus's neuropathogenesis remain poorly characterized. TiLV establishes a persistent infection in the brain of infected fi... Read More about Knowns and unknowns of TiLV-associated neuronal disease.

Development of Virus-like Particle Plant-Based Vaccines against Avian H5 and H9 Influenza A Viruses (2024)
Journal Article
Elbohy, O. A., Iqbal, M., Daly, J. M., & Dunham, S. P. (2024). Development of Virus-like Particle Plant-Based Vaccines against Avian H5 and H9 Influenza A Viruses. Veterinary Sciences, 11(2), Article 93. https://doi.org/10.3390/vetsci11020093

Avian influenza A virus (AIV) is a significant cause of mortality in poultry, causing substantial economic loss, particularly in developing countries, and has zoonotic potential. For example, highly pathogenic avian influenza (HPAI) viruses of the H5... Read More about Development of Virus-like Particle Plant-Based Vaccines against Avian H5 and H9 Influenza A Viruses.

Combined biolistic and cell penetrating peptide delivery for the development of scalable intradermal DNA vaccines (2024)
Journal Article
So, R. B., Li, G., Brentville, V., Daly, J. M., & Dixon, J. E. (2024). Combined biolistic and cell penetrating peptide delivery for the development of scalable intradermal DNA vaccines. Journal of Controlled Release, 367, 209-222. https://doi.org/10.1016/j.jconrel.2024.01.031

Physical-based gene delivery via biolistic methods (such as the Helios gene gun) involve precipitation of nucleic acids onto microparticles and direct transfection through cell membranes of exposed tissue (e.g. skin) by high velocity acceleration. Th... Read More about Combined biolistic and cell penetrating peptide delivery for the development of scalable intradermal DNA vaccines.

Systematic Review of Equine Influenza A Virus Vaccine Studies and Meta-Analysis of Vaccine Efficacy (2023)
Journal Article
Elliott, S., Olufemi, O. T., & Daly, J. M. (2023). Systematic Review of Equine Influenza A Virus Vaccine Studies and Meta-Analysis of Vaccine Efficacy. Viruses, 15(12), Article 2337. https://doi.org/10.3390/v15122337

Vaccines against equine influenza have been available since the late 1960s, but outbreaks continue to occur periodically, affecting both vaccinated and unvaccinated animals. The aim of this study was to systematically evaluate the efficacy of vaccine... Read More about Systematic Review of Equine Influenza A Virus Vaccine Studies and Meta-Analysis of Vaccine Efficacy.

Mapping Polyclonal Antibody Responses to Infection Using Next-Generation Phage Display (2023)
Book Chapter
Tsoumpeli, M. T., Varghese, A., Owen, J. P., Maddison, B. C., Daly, J. M., & Gough, K. C. (2023). Mapping Polyclonal Antibody Responses to Infection Using Next-Generation Phage Display. In M. Hust, & T. S. Lim (Eds.), Phage Display (467-487). Springer US. https://doi.org/10.1007/978-1-0716-3381-6_25

Peptide phage display has historically been used to epitope map monoclonal antibodies. More recently, by coupling this method with next-generation sequencing (so-called next-generation phage display, NGPD) to mass screen peptide binding events, the m... Read More about Mapping Polyclonal Antibody Responses to Infection Using Next-Generation Phage Display.

Comparative transcriptome analysis of spleen of Newcastle Disease Virus (NDV) infected chicken and Japanese quail: a potential role of NF-κβ pathway activation in NDV resistance (2023)
Journal Article
Panner Selvam, M. K., Kanagaraj, V., Kathaperumal, K., Nissly, R. H., Daly, J. M., & Kuchipudi, S. V. (2023). Comparative transcriptome analysis of spleen of Newcastle Disease Virus (NDV) infected chicken and Japanese quail: a potential role of NF-κβ pathway activation in NDV resistance. VirusDisease, 34(3), 402-409. https://doi.org/10.1007/s13337-023-00833-y

Newcastle disease (ND) affects a few hundred avian species including chicken and several species of domestic and wild birds. The clinical outcome of Newcastle disease virus (NDV) infection ranges from mild to severe fatal disease depending on the NDV... Read More about Comparative transcriptome analysis of spleen of Newcastle Disease Virus (NDV) infected chicken and Japanese quail: a potential role of NF-κβ pathway activation in NDV resistance.

Immune responses to Tilapia lake virus infection: what we know and what we don't know (2023)
Journal Article
Kembou-Ringert, J. E., Steinhagen, D., Thompson, K. D., Daly, J. M., & Adamek, M. (2023). Immune responses to Tilapia lake virus infection: what we know and what we don't know. Frontiers in Immunology, 14, Article 1240094. https://doi.org/10.3389/fimmu.2023.1240094

Tilapia lake virus (TiLV) is a novel contagious pathogen associated with a lethal disease affecting and decimating tilapia populations on several continents across the globe. Fish viral diseases, such as Tilapia lake virus disease (TiLVD), represent... Read More about Immune responses to Tilapia lake virus infection: what we know and what we don't know.

Advances in the understanding, detection and management of equine strangles (2023)
Journal Article
McLinden, L. A., Freeman, S. L., Daly, J., Blanchard, A., Kemp‐Symonds, J. G., & Waller, A. (2023). Advances in the understanding, detection and management of equine strangles. Equine Veterinary Education, 35(12), 662-672. https://doi.org/10.1111/eve.13845

Streptococcus equi subspecies equi (S. equi) is the causative organism of the upper respiratory disease of equids, strangles, characterised by pyrexia, lymphadenopathy and mucopurulent nasal discharge. Strangles was first reported over 750 years ago... Read More about Advances in the understanding, detection and management of equine strangles.

Tilapia Lake Virus Vaccine Development: A Review on the Recent Advances (2023)
Journal Article
Kembou-Ringert, J. E., Steinhagen, D., Readman, J., Daly, J. M., & Adamek, M. (2023). Tilapia Lake Virus Vaccine Development: A Review on the Recent Advances. Vaccines, 11(2), Article 251. https://doi.org/10.3390/vaccines11020251

Tilapia tilapinevirus (or tilapia lake virus, TiLV) is a recently emerging virus associated with a novel disease affecting and decimating tilapia populations around the world. Since its initial identification, TiLV has been reported in 17 countries,... Read More about Tilapia Lake Virus Vaccine Development: A Review on the Recent Advances.

Therapeutic Phage Display-Derived Single-Domain Antibodies for Pandemic Preparedness (2023)
Journal Article
Daly, J. M., Lim, T. S., & Gough, K. C. (2023). Therapeutic Phage Display-Derived Single-Domain Antibodies for Pandemic Preparedness. Antibodies, 12(1), Article 7. https://doi.org/10.3390/antib12010007

Driven by necessity, the COVID-19 pandemic caused by SARS-CoV-2 has accelerated the development and implementation of new vaccine platforms and other viral therapeutics. Among these is the therapeutic use of antibodies including single-domain antibod... Read More about Therapeutic Phage Display-Derived Single-Domain Antibodies for Pandemic Preparedness.

Seroprevalence of Equine Influenza and Its Associated Risk Factors in Northwest Nigeria (2022)
Journal Article
Olufemi, O. T., Edeh, E. R., Isyaku, M. S., Haliru, M., Samaila, S., Mshelia, P. W., …Daly, J. M. (2022). Seroprevalence of Equine Influenza and Its Associated Risk Factors in Northwest Nigeria. Pathogens, 11(11), Article 1372. https://doi.org/10.3390/pathogens11111372

Equine influenza (EI) is a fast-spreading respiratory disease of equids caused by equine influenza A virus (EIV), often resulting in high morbidity and a huge economic impact on the equine industry globally. In this cross-sectional study to determine... Read More about Seroprevalence of Equine Influenza and Its Associated Risk Factors in Northwest Nigeria.

Emergence of equine influenza virus H3Nx Florida clade 2 in Arabian racehorses in Egypt (2022)
Journal Article
Ahmed, B. M., Bayoumi, M. M., Farrag, M. A., Elgamal, A., Daly, J. M., & Amer, H. M. (2022). Emergence of equine influenza virus H3Nx Florida clade 2 in Arabian racehorses in Egypt. Virology Journal, 19, Article 185. https://doi.org/10.1186/s12985-022-01917-9

Background Equine influenza is an important cause of respiratory disease in equids. The causative virus; EIV, is highly variable and can evolve by accumulation of mutations, particularly in the haemagglutinin (HA) gene. Currently, H3N8 is the sole... Read More about Emergence of equine influenza virus H3Nx Florida clade 2 in Arabian racehorses in Egypt.

Epidemiology of equine influenza in the Maghreb area (2022)
Journal Article
Kareche, H., Daly, J. M., & Laabassi, F. (2022). Epidemiology of equine influenza in the Maghreb area. Comparative Immunology, Microbiology and Infectious Diseases, 89, Article 101868. https://doi.org/10.1016/j.cimid.2022.101868

Equine influenza (EI) is one of the most contagious respiratory infections in horses, donkeys and mules, caused by equine influenza A virus (EIV). It remains a disease with a strong economic stake for the equine industry. This review focuses on the e... Read More about Epidemiology of equine influenza in the Maghreb area.

An Equine Model for Vaccination against a Hepacivirus: Insights into Host Responses to E2 Recombinant Protein Vaccination and Subsequent Equine Hepacivirus Inoculation (2022)
Journal Article
Badenhorst, M., Saalmüller, A., Daly, J. M., Ertl, R., Stadler, M., Puff, C., …Cavalleri, J. V. (2022). An Equine Model for Vaccination against a Hepacivirus: Insights into Host Responses to E2 Recombinant Protein Vaccination and Subsequent Equine Hepacivirus Inoculation. Viruses, 14(7), Article 1401. https://doi.org/10.3390/v14071401

Equine hepacivirus (EqHV) is the closest known genetic homologue of hepatitis C virus. An effective prophylactic vaccine is currently not available for either of these hepaciviruses. The equine as potential surrogate model for hepacivirus vaccine stu... Read More about An Equine Model for Vaccination against a Hepacivirus: Insights into Host Responses to E2 Recombinant Protein Vaccination and Subsequent Equine Hepacivirus Inoculation.

Inference for a spatio-temporal model with partial spatial data: African horse sickness virus in Morocco (2022)
Journal Article
Fairbanks, E. L., Baylis, M., Daly, J. M., & Tildesley, M. J. (2022). Inference for a spatio-temporal model with partial spatial data: African horse sickness virus in Morocco. Epidemics, 39, Article 100566. https://doi.org/10.1016/j.epidem.2022.100566

African horse sickness virus (AHSV) is a vector-borne virus spread by midges (Culicoides spp.). The virus causes African horse sickness (AHS) disease in some species of equid. AHS is endemic in parts of Africa, previously emerged in Europe and in 2... Read More about Inference for a spatio-temporal model with partial spatial data: African horse sickness virus in Morocco.

Gene Expression Profile Induced by Two Different Variants of Street Rabies Virus in Mice (2022)
Journal Article
Appolinário, C. M., Daly, J. M., Emes, R. D., Marchi, F. A., Ribeiro, B. L. D., & Megid, J. (2022). Gene Expression Profile Induced by Two Different Variants of Street Rabies Virus in Mice. Viruses, 14(4), Article 692. https://doi.org/10.3390/v14040692

Pathogenicity and pathology of rabies virus (RABV) varies according to the variant, but the mechanisms are not completely known. In this study, gene expression profile in brains of mice experimentally infected with RABV isolated from a human case of... Read More about Gene Expression Profile Induced by Two Different Variants of Street Rabies Virus in Mice.

Development of Plant-Based Vaccines for Prevention of Avian Influenza and Newcastle Disease in Poultry (2022)
Journal Article
Nurzijah, I., Elbohy, O. A., Kanyuka, K., Daly, J. M., & Dunham, S. (2022). Development of Plant-Based Vaccines for Prevention of Avian Influenza and Newcastle Disease in Poultry. Vaccines, 10(3), Article 478. https://doi.org/10.3390/vaccines10030478

Viral diseases, including avian influenza (AI) and Newcastle disease (ND), are an important cause of morbidity and mortality in poultry, resulting in significant economic losses. Despite the availability of commercial vaccines for the major viral dis... Read More about Development of Plant-Based Vaccines for Prevention of Avian Influenza and Newcastle Disease in Poultry.

Re‐parameterization of a mathematical model of African horse sickness virus using data from a systematic literature search (2022)
Journal Article
Fairbanks, E. L., Brennan, M. L., Mertens, P. P. C., Tildesley, M. J., & Daly, J. M. (2022). Re‐parameterization of a mathematical model of African horse sickness virus using data from a systematic literature search. Transboundary and Emerging Diseases, 69(4), e671-e681. https://doi.org/10.1111/tbed.14420

African horse sickness (AHS) is a vector-borne disease transmitted by Culicoides spp., endemic to sub-Saharan Africa. There have been many examples of historic and recent outbreaks in the Middle East, Asia and Europe. However, not much is known about... Read More about Re‐parameterization of a mathematical model of African horse sickness virus using data from a systematic literature search.

Pentacyclic and hexacyclic cucurbitacins from Elaeocarpus petiolatus (2021)
Journal Article
Cho, E. S., Krishnan, P., Loh, H. S., Daly, J. M., Leong, C. O., Mai, C. W., …Lim, K. H. (2022). Pentacyclic and hexacyclic cucurbitacins from Elaeocarpus petiolatus. Phytochemistry, 193, Article 112988. https://doi.org/10.1016/j.phytochem.2021.112988

Four undescribed cucurbitacins, designated as petiolaticins A–D, and four known cucurbitacins were isolated from the bark and leaves of Elaeocarpus petiolatus (Jack) Wall. Their chemical structures were elucidated based on detailed analyses of the NM... Read More about Pentacyclic and hexacyclic cucurbitacins from Elaeocarpus petiolatus.

Serological Cross-Reactions between Expressed VP2 Proteins from Different Bluetongue Virus Serotypes (2021)
Journal Article
Fay, P. C., Mohd Jaafar, F., Batten, C., Attoui, H., Saunders, K., Lomonossoff, G. P., …Mertens, P. P. C. (2021). Serological Cross-Reactions between Expressed VP2 Proteins from Different Bluetongue Virus Serotypes. Viruses, 13(8), Article 1455. https://doi.org/10.3390/v13081455

Bluetongue (BT) is a severe and economically important disease of ruminants that is widely distributed around the world, caused by the bluetongue virus (BTV). More than 28 different BTV serotypes have been identified in serum neutralisation tests (SN... Read More about Serological Cross-Reactions between Expressed VP2 Proteins from Different Bluetongue Virus Serotypes.

A Scoping Review of West Nile Virus Seroprevalence Studies among African Equids (2021)
Journal Article
Olufemi, O. T., Barba, M., & Daly, J. M. (2021). A Scoping Review of West Nile Virus Seroprevalence Studies among African Equids. Pathogens, 10(7), Article 899. https://doi.org/10.3390/pathogens10070899

West Nile virus (WNV) is an emerging and re-emerging zoonotic flavivirus first identified in and endemic to Africa. The virus is transmitted between birds by biting mosquitoes, with equids and humans being incidental hosts. The majority of infected i... Read More about A Scoping Review of West Nile Virus Seroprevalence Studies among African Equids.

Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Service: A Mixed-Methods Study (2020)
Journal Article
Blake, H., Corner, J., Cirelli, C., Hassard, J., Briggs, L., Daly, J. M., …Ball, J. (2021). Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Service: A Mixed-Methods Study. International Journal of Environmental Research and Public Health, 18(1), 1-26. https://doi.org/10.3390/ijerph18010188

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. We aimed to explore student and staff perceptions and experiences of a pilot SARS-CoV-2 asymptomatic testing service (P-ATS) in a UK university campus setting. This was a mixed-method study co... Read More about Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Service: A Mixed-Methods Study.

Retrospective serological survey for influenza in horses from Brazil (2020)
Journal Article
Daly, J. M., Megid, J., Langoni, H., de Nardi Júnior, G., & Ribeiro, M. G. (2021). Retrospective serological survey for influenza in horses from Brazil. Brazilian Journal of Microbiology, 52(1), 461-466. https://doi.org/10.1007/s42770-020-00398-8

Equine influenza (EI) virus is one of the most economically important pathogens of respiratory diseases of horses worldwide. Despite availability of vaccines for control of EI, the highly contagious nature and variability properties of the virus mean... Read More about Retrospective serological survey for influenza in horses from Brazil.

Systematic review and meta?analysis of seroprevalence studies of West Nile virus in equids in Europe between 2001 and 2018 (2020)
Journal Article
Metz, M. B. C., Olufemi, O. T., Daly, J. M., & Barba, M. (2021). Systematic review and meta?analysis of seroprevalence studies of West Nile virus in equids in Europe between 2001 and 2018. Transboundary and Emerging Diseases, 68(4), 1814-1823. https://doi.org/10.1111/tbed.13866

There is some evidence that West Nile virus (WNV), which causes encephalomyelitis in equids, is an emerging disease in Europe. The aim of this study was to perform a systematic review and meta-analysis to determine the seroprevalence of West Nile vir... Read More about Systematic review and meta?analysis of seroprevalence studies of West Nile virus in equids in Europe between 2001 and 2018.

Evaluation of a pseudotyped virus neutralisation test for measurement of equine influenza A virus neutralizing antibody responses induced by vaccination and infection (2020)
Journal Article
Kinsley, R., Pronost, S., De Bock, M., Temperton, N., Daly, J. M., Paillot, R., & Scott, S. (2020). Evaluation of a pseudotyped virus neutralisation test for measurement of equine influenza A virus neutralizing antibody responses induced by vaccination and infection. Vaccines, 8(3), https://doi.org/10.3390/vaccines8030466

Equine influenza is a major respiratory disease of horses that is largely controlled by 24 vaccination in some equine populations. Virus-neutralizing antibodies, the mainstay of the protective 25 immune response, are problematic to assay for equine i... Read More about Evaluation of a pseudotyped virus neutralisation test for measurement of equine influenza A virus neutralizing antibody responses induced by vaccination and infection.

Serosurvey of pandemic H1N1 influenza A virus in dogs in Andalusia (southern Spain) (2020)
Journal Article
Jurado-Tarifa, E., Cano-Terriza, D., Daly, J. M., Arenas, A., & García-Bocanegra, I. (2020). Serosurvey of pandemic H1N1 influenza A virus in dogs in Andalusia (southern Spain). Zoonoses and Public Health, 67(8), 869-875. https://doi.org/10.1111/zph.12758

In April 2009, a new influenza A virus (IAV) subtype (A(H1N1)pdm09) spread worldwide and triggered the first human influenza pandemic of the 21st century. Since then, exposure to the pandemic H1N1 IAV has been confirmed in different animal species. S... Read More about Serosurvey of pandemic H1N1 influenza A virus in dogs in Andalusia (southern Spain).

Equine influenza vaccination as reported by horse owners and factors influencing their decision to vaccinate or not (2020)
Journal Article
Bambra, W., Daly, J. M., Kendall, N. R., Gardner, D. S., Brennan, M., & Kydd, J. H. (2020). Equine influenza vaccination as reported by horse owners and factors influencing their decision to vaccinate or not. Preventive Veterinary Medicine, 180, https://doi.org/10.1016/j.prevetmed.2020.105011

Background: Equine influenza virus is a highly contagious respiratory pathogen that causes pyrexia, anorexia, lethargy and coughing in immunologically naïve horses. Vaccines against equine influenza are available and vaccination is 20 mandatory for... Read More about Equine influenza vaccination as reported by horse owners and factors influencing their decision to vaccinate or not.

Equine viral encephalitis: prevalence, impact, and management strategies (2019)
Journal Article
Barba, M., Fairbanks, E., & Daly, J. M. (2019). Equine viral encephalitis: prevalence, impact, and management strategies. Veterinary Medicine: Research and Reports, 2019(10), 99-110. https://doi.org/10.2147/VMRR.S168227

Members of several different virus families cause equine viral encephalitis, the majority of which are arthropod-borne viruses (arboviruses) with zoonotic potential. The clinical signs caused are rarely pathognomonic; therefore, a clinical diagnosis... Read More about Equine viral encephalitis: prevalence, impact, and management strategies.

Bluetongue virus outer-capsid protein VP2 expressed in Nicotiana Nicotiana benthamiana raises neutralising antibodies and a protective immune response in IFNAR -/- mice (2019)
Journal Article
Fay, P. C., Attoui, H., Batten, C., Mohd Jaafar, F., Lomonossoff, G. P., Daly, J. M., & Mertens, P. P. (2019). Bluetongue virus outer-capsid protein VP2 expressed in Nicotiana Nicotiana benthamiana raises neutralising antibodies and a protective immune response in IFNAR -/- mice. Vaccine, 2, Article 100026. https://doi.org/10.1016/j.jvacx.2019.100026

Bluetongue is a severe, economically important disease of ruminants that is widely distributed in tropical and temperate regions around the world. It is associated with major production losses, restrictions of animal movements and trade, as well as c... Read More about Bluetongue virus outer-capsid protein VP2 expressed in Nicotiana Nicotiana benthamiana raises neutralising antibodies and a protective immune response in IFNAR -/- mice.

The challenges posed by equine arboviruses (2018)
Journal Article
Chapman, G. E., Baylis, M., Archer, D., & Daly, J. M. (2018). The challenges posed by equine arboviruses. Equine Veterinary Journal, 50(4), 436-445. https://doi.org/10.1111/evj.12829

Equine populations worldwide are at increasing risk of infection by viruses transmitted by biting arthropods including mosquitoes, biting midges (Culicoides), sandflies and ticks. These include the flaviviruses (Japanese encephalitis, West Nile and M... Read More about The challenges posed by equine arboviruses.

Epidemiological survey of equine influenza in Andalusia, Spain (2018)
Journal Article
Jurado-Tarifa, E., Daly, J. M., Pérez-Écija, A., Barba-Recreo, M., Mendoza, F., Al-Shuwaikh, A., & García-Bocanegra, I. (2018). Epidemiological survey of equine influenza in Andalusia, Spain. Preventive Veterinary Medicine, 151, https://doi.org/10.1016/j.prevetmed.2018.01.003

Equine influenza is a highly contagious respiratory disease considered the most important respiratory disease in equids. Although influenza A virus (IAV) has caused outbreaks in equids worldwide, surveillance on these species in Spain has not been co... Read More about Epidemiological survey of equine influenza in Andalusia, Spain.

How is Europe positioned for a re-emergence of Schmallenberg virus? (2017)
Journal Article
Tarlinton, R., Gough, K., Maddison, B., Stavrou, A., Daly, J. M., Maddison, B. C., …Tarlinton, R. E. (2017). How is Europe positioned for a re-emergence of Schmallenberg virus?. Veterinary Journal, 230, 45-51. https://doi.org/10.1016/j.tvjl.2017.04.009

The Schmallenberg virus (SBV) caused a large scale epidemic in Europe from 2011–2013 infecting ruminants and causing fetal deformities after infection of pregnant animals. The main impacts of the virus were financial losses due to animal, meat and se... Read More about How is Europe positioned for a re-emergence of Schmallenberg virus?.

A multi-national European cross-sectional study of feline calicivirus epidemiology, diversity and vaccine cross-reactivity (2017)
Journal Article
Afonso, M. M., Pinchbeck, G. L., Smith, S. L., Daly, J. M., Gaskell, R. M., Dawson, S., & Radford, A. D. (2017). A multi-national European cross-sectional study of feline calicivirus epidemiology, diversity and vaccine cross-reactivity. Vaccine, 35(20), 2753-2760. https://doi.org/10.1016/j.vaccine.2017.03.030

Background Feline calicivirus (FCV) is an important pathogen of cats for which vaccination is regularly practised. Long-term use of established vaccine antigens raises the theoretical possibility that field viruses could become resistant. This stu... Read More about A multi-national European cross-sectional study of feline calicivirus epidemiology, diversity and vaccine cross-reactivity.

The optimisation of Pseudotyped viruses for the characterisation of immune responses to equine influenza virus (2016)
Journal Article
Scott, S. D., Kinsley, R., Temperton, N., & Daly, J. M. (2016). The optimisation of Pseudotyped viruses for the characterisation of immune responses to equine influenza virus. Pathogens, 5(4), Article 68. https://doi.org/10.3390/pathogens5040068

Pseudotyped viruses (PVs) produced by co-transfecting cells with plasmids expressing lentiviral core proteins and viral envelope proteins are potentially powerful tools for studying various aspects of equine influenza virus (EIV) biology. The aim of... Read More about The optimisation of Pseudotyped viruses for the characterisation of immune responses to equine influenza virus.

Canine parvovirus (CPV-2) variants circulating in Nigerian dogs (2016)
Journal Article
Apaa, T., Daly, J. M., & Tarlinton, R. E. (2016). Canine parvovirus (CPV-2) variants circulating in Nigerian dogs. Veterinary Record Open, 3(1), Article e000198. https://doi.org/10.1136/vetreco-2016-000198

Canine parvovirus type 2 (CPV-2) is a highly contagious viral disease with three variants (CPV-2a, CPV-2b and CPV-2c) currently circulating in dogs worldwide. The main aim of this study was to determine the prevalent CPV-2 variant in faecal samples f... Read More about Canine parvovirus (CPV-2) variants circulating in Nigerian dogs.

The influenza NS1 protein: what do we know in equine influenza virus pathogenesis? (2016)
Journal Article
Barba, M., & Daly, J. M. (2016). The influenza NS1 protein: what do we know in equine influenza virus pathogenesis?. Pathogens, 5(3), Article 57. https://doi.org/10.3390/pathogens5030057

Equine influenza virus remains a serious health and potential economic problem throughout most parts of the world, despite intensive vaccination programs in some horse populations. The influenza non-structural protein 1 (NS1) has multiple functions i... Read More about The influenza NS1 protein: what do we know in equine influenza virus pathogenesis?.

Small animal disease surveillance: respiratory disease (2016)
Journal Article
Sánchez-Vizcaíno, F., Daly, J. M., Jones, P. H., Dawson, S., Gaskell, R., Menacere, T., …Radford, A. D. (2016). Small animal disease surveillance: respiratory disease. Veterinary Record, 178(15), 361-364. https://doi.org/10.1136/vr.i1815

This second Small Animal Disease Surveillance report focuses on syndromic surveillance of i) respiratory disease in veterinary practice and ii) feline calicivirus (FCV) based on laboratory diagnosis, in a large veterinary-visiting pet population of t... Read More about Small animal disease surveillance: respiratory disease.

Controlling equine influenza: Traditional to next generation serological assays (2016)
Journal Article
Kinsley, R., Scott, S. D., & Daly, J. M. (2016). Controlling equine influenza: Traditional to next generation serological assays. Veterinary Microbiology, 187, 15-20. https://doi.org/10.1016/j.vetmic.2016.03.006

Serological assays provide an indirect route for the recognition of infectious agents via the detection of antibodies against the infectious agent of interest within serum. Serological assays for equine influenza A virus can be applied for different... Read More about Controlling equine influenza: Traditional to next generation serological assays.

Technical considerations for the generation of novel pseudotyped viruses (2016)
Journal Article
King, B., Temperton, N., Grehan, K., Scott, S. D., Wright, E., Tarr, A. W., & Daly, J. M. (2016). Technical considerations for the generation of novel pseudotyped viruses. Future Virology, 11(1), https://doi.org/10.2217/fvl.15.106

A pseudotyped virus (PV) is a virus particle with an envelope protein originating from a different virus. The ability to dictate which envelope proteins are expressed on the surface has made pseudotyping an important tool for basic virological studie... Read More about Technical considerations for the generation of novel pseudotyped viruses.

Modulation of potassium channels inhibits bunyavirus infection (2015)
Journal Article
Hover, S., King, B., Hall, B., Loundras, E., Taqi, H., Daly, J. M., …Mankouri, J. (2016). Modulation of potassium channels inhibits bunyavirus infection. Journal of Biological Chemistry, 291(7), 3411-3422. https://doi.org/10.1074/jbc.M115.692673

Bunyaviruses are considered to be emerging pathogens facilitated by the segmented nature of their genome that allows reassortment between different species to generate novel viruses with altered pathogenicity. Bunyaviruses are transmitted via a diver... Read More about Modulation of potassium channels inhibits bunyavirus infection.

Diversity of group A rotavirus on a UK pig farm (2015)
Journal Article
Chandler-Bostock, R., Hancox, L., Payne, H., Iturriza-Gomara, M., Daly, J. M., & Mellits, K. (2015). Diversity of group A rotavirus on a UK pig farm. Veterinary Microbiology, 180(3-4), 205-211. https://doi.org/10.1016/j.vetmic.2015.09.009

Group A rotaviruses (GARV) are a significant cause of enteritis in young pigs. The aim of this study was to extend our understanding of the molecular epidemiology of porcine GARV in the UK by investigating the genetic diversity of GARV on a conventio... Read More about Diversity of group A rotavirus on a UK pig farm.

Seroprevalence of Schmallenberg virus in the United Kingdom and the Republic of Ireland: 2011-2013 (2015)
Journal Article
Tarlinton, R., King, B., O'Shea Brown, T., & Daly, J. M. (2015). Seroprevalence of Schmallenberg virus in the United Kingdom and the Republic of Ireland: 2011-2013. Veterinary Microbiology, 180(1-2), 36-40. https://doi.org/10.1016/j.vetmic.2015.07.025

© 2015 Elsevier B.V. Since its identification in late 2011, Schmallenberg virus (SBV) spread rapidly across Europe. Using archived samples from domestic ruminants collected between October 2011 and June 2013, the seroprevalence in the United Kingdom... Read More about Seroprevalence of Schmallenberg virus in the United Kingdom and the Republic of Ireland: 2011-2013.

Identification of morphological differences between avian influenza A viruses grown in chicken and duck cells (2015)
Journal Article
Al-Mubarak, F., Daly, J., Christie, D., Fountain, D., & Dunham, S. P. (2015). Identification of morphological differences between avian influenza A viruses grown in chicken and duck cells. Virus Research, 199, 9-19. https://doi.org/10.1016/j.virusres.2015.01.005

Although wild ducks are considered to be the major reservoirs for most influenza A virus subtypes, they are typically resistant to the effects of the infection. In contrast, certain influenza viruses may be highly pathogenic in other avian hosts such... Read More about Identification of morphological differences between avian influenza A viruses grown in chicken and duck cells.

Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows (2015)
Journal Article
Daly, J. M., King, B., Tarlinton, R. A., Gough, K. C., Maddison, B. C., & Blowey, R. (2015). Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows. BMC Veterinary Research, 11, Article 56. https://doi.org/10.1186/s12917-015-0365-1

© Daly et al.; licensee BioMed Central. Background: Schmallenberg virus (SBV) is a recently emerged virus of ruminants in Europe. Enzyme-linked immunosorbent assays (ELISA) are commonly used to detect SBV-specific antibodies in bulk tank milk samples... Read More about Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows.

High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza A virus resistance (2014)
Journal Article
Seng, L., Daly, J. M., Chang, K., & Kuchipudi, S. V. (2014). High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza A virus resistance. PLoS ONE, 9, Article e109023. https://doi.org/10.1371/journal.pone.0109023

Respiratory epithelial cells play a key role in influenza A virus (IAV) pathogenesis and host innate response. Transformed human respiratory cell lines are widely used in the study of IAV?host interactions due to their relative convenience, and inher... Read More about High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza A virus resistance.

Development of a surveillance scheme for equine influenza in the UK and characterisation of viruses isolated in Europe, Dubai and the USA from 2010-2012 (2014)
Journal Article
Woodward, A. L., Rash, A. S., Blinman, D., Bowman, S., Chambers, T. M., Daly, J. M., …Elton, D. M. (2014). Development of a surveillance scheme for equine influenza in the UK and characterisation of viruses isolated in Europe, Dubai and the USA from 2010-2012. Veterinary Microbiology, 169(3-4), https://doi.org/10.1016/j.vetmic.2013.11.039

Equine influenza viruses are a major cause of respiratory disease in horses worldwide and undergo antigenic drift. Several outbreaks of equine influenza occurred worldwide during 2010-2012, including in vaccinated animals, highlighting the importance... Read More about Development of a surveillance scheme for equine influenza in the UK and characterisation of viruses isolated in Europe, Dubai and the USA from 2010-2012.

Potential of a sequence-based antigenic distance measure to indicate equine influenza vaccine strain efficacy (2013)
Journal Article
Daly, J. M., & Elton, D. (2013). Potential of a sequence-based antigenic distance measure to indicate equine influenza vaccine strain efficacy. Vaccine, 31(51), https://doi.org/10.1016/j.vaccine.2013.06.070

The calculation of pepitope values, a sequence-based measure of antigenic distance between strains, was developed for human influenza. The potential to apply the pepitope value to equine influenza vaccine strain selection was assessed. There was a ne... Read More about Potential of a sequence-based antigenic distance measure to indicate equine influenza vaccine strain efficacy.

The genetics of virus particle shape in equine influenza A virus (2013)
Journal Article
Elton, D., Bruce, E. A., Bryant, N., Wise, H. M., MacRae, S., Rash, A., …Digard, P. (2013). The genetics of virus particle shape in equine influenza A virus. Influenza and Other Respiratory Viruses, 7(s4), https://doi.org/10.1111/irv.12197

Background Many human strains of influenza A virus produce highly pleomorphic virus particles that at the extremes can be approximated as either spheres of around 100 nm diameter or filaments of similar cross-section but elongated to lengths of many... Read More about The genetics of virus particle shape in equine influenza A virus.

What can mathematical models bring to the control of equine influenza? (2013)
Journal Article
Daly, J. M., Newton, J., Wood, J., & Park, A. (in press). What can mathematical models bring to the control of equine influenza?. Equine Veterinary Journal, 45(6), https://doi.org/10.1111/evj.12104

Mathematical modelling of infectious disease is increasingly regarded as an important tool in the development of disease prevention and control measures. This article brings together key findings from various modelling studies conducted over the past... Read More about What can mathematical models bring to the control of equine influenza?.

Current progress with serological assays for exotic emerging / re-emerging viruses (2013)
Journal Article
Mather, S., Scott, S., Temperton, N., Wright, E., King, B., & Daly, J. (2013). Current progress with serological assays for exotic emerging / re-emerging viruses. Future Virology, 8(8), https://doi.org/10.2217/fvl.13.60

Recent decades have witnessed an unprecedented rise in the outbreak occurrence of infectious and primarily zoonotic viruses. Contributing factors to this phenomenon include heightened global connectivity via air travel and international trade links,... Read More about Current progress with serological assays for exotic emerging / re-emerging viruses.

Evolution of equine influenza virus in vaccinated horses (2013)
Journal Article
Murcia, P. R., Baillie, G. J., Stack, J. C., Jervis, C., Elton, D., Mumford, J. A., …Wood, J. L. (2013). Evolution of equine influenza virus in vaccinated horses. Journal of Virology, 87(8), https://doi.org/10.1128/JVI.03379-12

Influenza A viruses are characterized by their ability to evade host immunity, even in vaccinated individuals. To determine how prior immunity shapes viral diversity in vivo, we studied the intra- and interhost evolution of equine influenza virus in... Read More about Evolution of equine influenza virus in vaccinated horses.

The challenge of Schmallenberg virus emergence in Europe (2012)
Journal Article
Tarlinton, R., Daly, J. M., Dunham, S. P., & Kydd, J. M. (2012). The challenge of Schmallenberg virus emergence in Europe. Veterinary Journal, 194(1), 10-18. https://doi.org/10.1016/j.tvjl.2012.08.017

The large-scale outbreak of disease across Northern Europe caused by a new orthobunyavirus known as Schmallenberg virus has caused considerable disruption to lambing and calving. Although advances in technology and collaboration between veterinary... Read More about The challenge of Schmallenberg virus emergence in Europe.

Perceptions and Experiences of the University of Nottingham Pilot Asymptomatic Testing Service: A Mixed-Methods Study
Working Paper
Blake, H., Corner, J., Cirelli, C., Hassard, J., Briggs, L., Daly, J. M., …Ball, J. Perceptions and Experiences of the University of Nottingham Pilot Asymptomatic Testing Service: A Mixed-Methods Study

We aimed to explore student and staff perceptions and experiences of a pilot COVID-19 asymptomatic testing service (P-ATS) in a UK university campus setting. This was a mixed-method study comprised of an online survey, and thematic analysis of qualit... Read More about Perceptions and Experiences of the University of Nottingham Pilot Asymptomatic Testing Service: A Mixed-Methods Study.

Troubleshooting methods for the generation of novel pseudotyped viruses
Journal Article
King, B., Temperton, N., Grehan, K., Scott, S., Wright, E., Tarr, A. W., & Daly, J. M. Troubleshooting methods for the generation of novel pseudotyped viruses. Future Virology,

A pseudotyped virus (PV) is a virus particle with an envelope protein originating from a different virus. The ability to dictate which envelope proteins are expressed on the surface has made pseudotyping an important tool for basic virological studie... Read More about Troubleshooting methods for the generation of novel pseudotyped viruses.