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Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial (2022)
Journal Article
Hancox, J., Ayling, K., Bedford, L., Vedhara, K., Robertson, J. F. R., Young, B., …Kendrick., D. (2023). Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial. Journal of Public Health, 45(2), e275–e284. https://doi.org/10.1093/pubmed/fdac032

Background: The Early CDT®-Lung antibody blood test plus serial CT-scans for test-positives reduces late-stage lung cancer presentation. This study assessed psychological outcomes of this approach. Methods: Randomised controlled trial (n=12,208) c... Read More about Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial.

The prevalence, incidence, prognosis and risk factors for symptoms of depression and anxiety in a UK cohort during the COVID-19 pandemic (2022)
Journal Article
Jia, R., Ayling, K., Chalder, T., Massey, A., Gasteiger, N., Broadbent, E., …Vedhara, K. (2022). The prevalence, incidence, prognosis and risk factors for symptoms of depression and anxiety in a UK cohort during the COVID-19 pandemic. BJPsych Open, 8(2), Article e64. https://doi.org/10.1192/bjo.2022.34

Background The COVID-19 pandemic has had profound consequences for population mental health. However, it is less clear for whom these effects are sustained. Aims To investigate the prevalence, incidence, prognosis and risk factors for symptoms of dep... Read More about The prevalence, incidence, prognosis and risk factors for symptoms of depression and anxiety in a UK cohort during the COVID-19 pandemic.

The Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer (2022)
Journal Article
Shanmugavadivel, D., Liu, J., Ball-Gamble, A., Polanco, A., Vedhara, K., Walker, D., & Ojha, S. (2022). The Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer. BMJ Open, 12(2), Article e058744. https://doi.org/10.1136/bmjopen-2021-058744

Introduction: Childhood cancer is diagnosed in 400 000 children and young people (CYP) aged 0–19 years worldwide annually. In the UK, a child’s cumulative cancer risk increases from 1 in 4690 from birth to aged 1, to 1 in 470 by age 15. Once diagnose... Read More about The Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer.

Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer (2022)
Journal Article
Shanmugavadivel, D., Liu, J., Gamble, A., Polanco, A., Vedhara, K., Walker, D., & Ojha, S. (2022). Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer. BMJ Open, 12(2), Article e058744. https://doi.org/10.1136/bmjopen-2021-058744

Introduction: Childhood cancer is diagnosed in 400,000 children and young people (CYP) aged 0-19 years worldwide annually. In the UK, a child’s cumulative cancer risk increases from 1 in 4690 from birth to aged 1, to 1 in 470 by age 15. Once diagnose... Read More about Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer.

Relationship between Anxiety, Depression, and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Proof of Concept (2022)
Journal Article
Vedhara, K., Ayling, K., Jia, R., Fairclough, L., Morling, J. R., Ball, J. K., …Tighe, P. (2022). Relationship between Anxiety, Depression, and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Proof of Concept. Journal of Infectious Diseases, 225(12), 2137-2141. https://doi.org/10.1093/infdis/jiac006

Background: Psychological factors can influence susceptibility to viral infections. We examined whether such influences are evident in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Methods: Participants (n=102) completed mea... Read More about Relationship between Anxiety, Depression, and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Proof of Concept.

Psychological Predictors of Self-reported COVID-19 Outcomes: Results From a Prospective Cohort Study (2022)
Journal Article
Ayling, K., Jia, R., Coupland, C., Chalder, T., Massey, A., Broadbent, E., & Vedhara, K. (2022). Psychological Predictors of Self-reported COVID-19 Outcomes: Results From a Prospective Cohort Study. Annals of Behavioral Medicine, 56(5), 484-497. https://doi.org/10.1093/abm/kaab106

Background: Previous research has shown that psychological factors, such as stress and social support, are associated with greater susceptibility to viral respiratory illnesses and more severe symptoms. During the COVID-19 pandemic there has been a w... Read More about Psychological Predictors of Self-reported COVID-19 Outcomes: Results From a Prospective Cohort Study.

The Association of Lifestyle and Mood with Long-Term Levels of Cortisol: A Systematic Review (2022)
Journal Article
Jia, R., Carlisle, S., & Vedhara, K. (2022). The Association of Lifestyle and Mood with Long-Term Levels of Cortisol: A Systematic Review. Cogent Psychology, 9(1), Article 2036487. https://doi.org/10.1080/23311908.2022.2036487

Objectives: To critically review evidence for associations between long-term cortisol levels, mood, and lifestyle factors. Method: Systematic searches of electronic databases (MEDLINE, EMBASE, PsycINFO, WoS, and CINAHL) were conducted up to 21/11/... Read More about The Association of Lifestyle and Mood with Long-Term Levels of Cortisol: A Systematic Review.

Understanding and addressing vaccine hesitancy in the context of COVID-19: development of a digital intervention (2021)
Journal Article
Knight, H., Jia, R., Ayling, K., Bradbury, K., Baker, K., Chalder, T., …Vedhara, K. (2021). Understanding and addressing vaccine hesitancy in the context of COVID-19: development of a digital intervention. Public Health, 201, 98-107. https://doi.org/10.1016/j.puhe.2021.10.006

Objectives: Severe Acute Respiratory Coronavirus 2 (SARS-CoV-2) was identified in late 2019, spreading to over 200 countries and resulting in almost two million deaths worldwide. The emergence of safe and effective vaccines provides a route out of th... Read More about Understanding and addressing vaccine hesitancy in the context of COVID-19: development of a digital intervention.

Impacts of the COVID-19 pandemic and self-isolation on students and staff in higher education: A qualitative study (2021)
Journal Article
Knight, H., Carlisle, S., O’connor, M., Briggs, L., Fothergill, L., Al-Oraibi, A., …Blake, H. (2021). Impacts of the COVID-19 pandemic and self-isolation on students and staff in higher education: A qualitative study. International Journal of Environmental Research and Public Health, 18(20), Article 10675. https://doi.org/10.3390/ijerph182010675

This qualitative study explored the impact of COVID-19 self-isolation and social restriction measures on university students, through the perspectives of both students and the staff supporting them. The study comprised 11 focus groups (students) and... Read More about Impacts of the COVID-19 pandemic and self-isolation on students and staff in higher education: A qualitative study.

The effect of choice interventions on retention-related, behavioural and mood outcomes: a systematic review with meta-analysis (2021)
Journal Article
Carlisle, S., Ayling, K., Jia, R., Buchanan, H., & Vedhara, K. (2022). The effect of choice interventions on retention-related, behavioural and mood outcomes: a systematic review with meta-analysis. Health Psychology Review, 16(2), 220-256. https://doi.org/10.1080/17437199.2021.1962386

The provision of choice within interventions has been associated with increased motivation, engagement and interest, as well as improved clinical outcomes. Existing reviews are limited by their wide inclusion criteria or by not assessing behaviour ch... Read More about The effect of choice interventions on retention-related, behavioural and mood outcomes: a systematic review with meta-analysis.

Prospective examination of mental health in university students during the COVID-19 pandemic (2021)
Working Paper
Jia, R., Knight, H., Ayling, K., Coupland, C., Corner, J., Denning, C., …Vedhara, K. Prospective examination of mental health in university students during the COVID-19 pandemic

Background The impact of changing social restrictions on the mental health of students during the COVID-19 pandemic warrants exploration. Aims To prospectively examine changes to university students’ mental health during the pandemic. Methods S... Read More about Prospective examination of mental health in university students during the COVID-19 pandemic.

The more the merrier! Barriers and facilitators to the general public’s use of a COVID-19 contact tracing app in New Zealand (2021)
Journal Article
Gasteiger, N., Gasteiger, C., Vedhara, K., & Broadbent, E. (2022). The more the merrier! Barriers and facilitators to the general public’s use of a COVID-19 contact tracing app in New Zealand. Informatics for Health and Social Care, 47(2), 132-143. https://doi.org/10.1080/17538157.2021.1951274

Contact tracing for infectious diseases can be partially automated using mobile applications. However, the success of these tools is dependent on significant uptake and frequent use by the public. This study explored the barriers and facilitators to... Read More about The more the merrier! Barriers and facilitators to the general public’s use of a COVID-19 contact tracing app in New Zealand.

Depression, anxiety and stress during the COVID-19 pandemic: results from a New Zealand cohort study on mental well-being (2021)
Journal Article
Gasteiger, N., Vedhara, K., Massey, A., Jia, R., Ayling, K., Chalder, T., …Broadbent, E. (2021). Depression, anxiety and stress during the COVID-19 pandemic: results from a New Zealand cohort study on mental well-being. BMJ Open, 11(5), Article e045325. https://doi.org/10.1136/bmjopen-2020-045325

Objectives: The COVID-19 pandemic has caused unprecedented disruption to daily life. This study investigated depression, anxiety and stress in New Zealand (NZ) during the first ten weeks of the COVID-19 pandemic, and associated psychological and beha... Read More about Depression, anxiety and stress during the COVID-19 pandemic: results from a New Zealand cohort study on mental well-being.

Students’ views towards sars-cov-2 mass asymptomatic testing, social distancing and self-isolation in a university setting during the covid-19 pandemic: A qualitative study (2021)
Journal Article
Blake, H., Knight, H., Jia, R., Corner, J., Morling, J. R., Denning, C., …Vedhara, K. (2021). Students’ views towards sars-cov-2 mass asymptomatic testing, social distancing and self-isolation in a university setting during the covid-19 pandemic: A qualitative study. International Journal of Environmental Research and Public Health, 18(8), Article 4182. https://doi.org/10.3390/ijerph18084182

We aimed to explore university students’ perceptions and experiences of SARS-CoV-2 mass asymptomatic testing, social distancing and self-isolation, during the COVID-19 pandemic. This qualitative study comprised of four rapid online focus groups condu... Read More about Students’ views towards sars-cov-2 mass asymptomatic testing, social distancing and self-isolation in a university setting during the covid-19 pandemic: A qualitative study.

Students’ Views Towards SARS-CoV-2 Mass Asymptomatic Testing, Social Distancing and Self-Isolation in a University Setting during the COVID-19 Pandemic: A Qualitative Study (2021)
Working Paper
Blake, H., Knight, H., Jia, R., Corner, J., Morling, J. R., Denning, C., …Vedhara, K. Students’ Views Towards SARS-CoV-2 Mass Asymptomatic Testing, Social Distancing and Self-Isolation in a University Setting during the COVID-19 Pandemic: A Qualitative Study

We aimed to explore university students’ perceptions and experiences of SARS-CoV-2 mass asymptomatic testing, social distancing and self-isolation during the COVID-19 pandemic. This qualitative study comprised of four rapid online focus groups conduc... Read More about Students’ Views Towards SARS-CoV-2 Mass Asymptomatic Testing, Social Distancing and Self-Isolation in a University Setting during the COVID-19 Pandemic: A Qualitative Study.

Experiences of the COVID-19 pandemic: cross-sectional analysis of risk perceptions and mental health in a student cohort (2020)
Working Paper
Jia, R., Knight, H., Blake, H., Corner, J., Denning, C., Ball, J., …Vedhara, K. Experiences of the COVID-19 pandemic: cross-sectional analysis of risk perceptions and mental health in a student cohort

Objective: This study examined the COVID-19 risk perceptions and mental health of university students on returning to campus in the midst of the COVID-19 pandemic. Methods: An online survey was completed during the first four weeks of the academic... Read More about Experiences of the COVID-19 pandemic: cross-sectional analysis of risk perceptions and mental health in a student cohort.

Effects of non-pharmacological interventions as vaccine adjuvants in humans: a systematic review and network meta-analysis (2020)
Journal Article
Vedhara, K., Royal, S., Sunger, K., Caldwell, D. M., Halliday, V., Taylor, C. M., …Welton, N. J. (2021). Effects of non-pharmacological interventions as vaccine adjuvants in humans: a systematic review and network meta-analysis. Health Psychology Review, 15(2), 245-271. https://doi.org/10.1080/17437199.2020.1854050

© 2020 Informa UK Limited, trading as Taylor & Francis Group. Introduction: Psychological and behavioural may enhance vaccine effectiveness. We conducted a systematic review and network meta-analysis (NMA) to examine the effects of non-pharmacologi... Read More about Effects of non-pharmacological interventions as vaccine adjuvants in humans: a systematic review and network meta-analysis.

Young people, mental health and COVID-19 infection: The canaries we put in the coal-mine (2020)
Journal Article
Jia, R., Ayling, K., Chalder, T., Coupland, C., Massey, A., Broadbent, E., …Vedhara, K. (2020). Young people, mental health and COVID-19 infection: The canaries we put in the coal-mine. Public Health, 189, 158-161. https://doi.org/10.1016/j.puhe.2020.10.018

Background: The number of people testing positive for SARS-COV-2 in the UK, particularly among young adults, is increasing. We report here on the mental health of young adults and related psychological and behavioural responses to the pandemic, and c... Read More about Young people, mental health and COVID-19 infection: The canaries we put in the coal-mine.

Mental health in the UK during the COVID-19 pandemic: cross-sectional analyses from a community cohort study (2020)
Journal Article
Jia, R., Ayling, K., Chalder, T., Massey, A., Broadbent, E., Coupland, C., & Vedhara, K. (2020). Mental health in the UK during the COVID-19 pandemic: cross-sectional analyses from a community cohort study. BMJ Open, 10(9), Article e040620. https://doi.org/10.1136/bmjopen-2020-040620

Objectives: Previous pandemics have resulted in significant consequences for mental health. Here, we report the mental health sequelae of the COVID-19 pandemic in a UK cohort and examine modifiable and non-modifiable explanatory factors associated wi... Read More about Mental health in the UK during the COVID-19 pandemic: cross-sectional analyses from a community cohort study.