AR's and AD's post-war editorial policies: the making of modern architecture in Britain
(2012)
Journal Article
All Outputs (668)
Bacterial involvement in otitis media with effusion (2012)
Journal Article
Objective Otitis media with effusion (OME), a common chronic childhood condition affecting hearing, is thought to be a result of bacterial infection, with biofilms recently implicated. Although bacterial DNA can be detected by polymerase chain react... Read More about Bacterial involvement in otitis media with effusion.
The conceptual framing, design and evaluation of device ecologies for collaborative activities (2012)
Journal Article
A variety of computing technologies, in addition to the personal computer, are now commonly used in many settings. As networking infrastructures mature, it is increasingly feasible and affordable to consider closer integration and use of these hetero... Read More about The conceptual framing, design and evaluation of device ecologies for collaborative activities.
Multiscale modelling of auxin transport in the plant-root elongation zone (2012)
Journal Article
In the root elongation zone of a plant, the hormone auxin moves in a polar manner due to active transport facilitated by spatially distributed influx and efflux carriers present on the cell membranes. To understand how the cell-scale active transport... Read More about Multiscale modelling of auxin transport in the plant-root elongation zone.
Medical device design in context: a model of user–device interaction and consequences (2012)
Journal Article
The practice of evaluating interaction with devices is embedded in disciplines such as human-computer interaction and cognitive ergonomics, including concepts such as affordances, error analysis, skill, rule and knowledge based behaviour and decision... Read More about Medical device design in context: a model of user–device interaction and consequences.
Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis (2012)
Journal Article
Pseudomonas aeruginosa chronically infects patients with cystic fibrosis and is associated with greater morbidity. There has been limited progress on the clinical development of new antibiotics with novel modes of action. This review addresses some o... Read More about Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis.
Rank-based model selection for multiple ions quantum tomography (2012)
Journal Article
The statistical analysis of measurement data has become a key component of many quantum engineering experiments. As standard full state tomography becomes unfeasible for large dimensional quantum systems, one needs to exploit prior information and th... Read More about Rank-based model selection for multiple ions quantum tomography.
Beyond resistance and nationalism: local history and the case of Afaq Khoja (2012)
Journal Article
Kashgar's seventeenth-century ruler-saint, Afaq Khoja, is remarkable for the amount of historical writing he has inspired, both outside and within Chinese Turkestan. His reputation among Uyghur historians is one of the few aspects of local Uyghur his... Read More about Beyond resistance and nationalism: local history and the case of Afaq Khoja.
Background Long-term analysis of a randomised trial in Nottingham comparing tamoxifen versus surgery as initial treatment demonstrated that in oestrogen receptor (ER)-unselected cases, surgery achieved better local control, with no difference in ove... Read More about A randomised trial of primary tamoxifen versus mastectomy plus adjuvant tamoxifen in fit elderly women with invasive breast carcinoma of high oestrogen receptor content: long-term results at 20 years of follow-up.
A new model and a hyper-heuristic approach for two-dimensional shelf space allocation (2012)
Journal Article
In this paper, we propose a two-dimensional shelf space allocation model. The second dimension stems from the height of the shelf. This results in an integer nonlinear programming model with a complex form of objective function. We propose a multiple... Read More about A new model and a hyper-heuristic approach for two-dimensional shelf space allocation.
Future bronchodilator therapy: a bitter pill to swallow? (2012)
Journal Article
The challenge of Schmallenberg virus emergence in Europe (2012)
Journal Article
The large-scale outbreak of disease across Northern Europe caused by a new orthobunyavirus known as Schmallenberg virus has caused considerable disruption to lambing and calving. Although advances in technology and collaboration between veterinary... Read More about The challenge of Schmallenberg virus emergence in Europe.
Cost effectiveness of epidural steroid injections to manage chronic lower back pain (2012)
Journal Article
Background The efficacy of epidural steroid injections in the management of chronic low back pain is disputed, yet the technique remains popular amongst physicians and patients alike. This study assesses the cost effectiveness of injections administ... Read More about Cost effectiveness of epidural steroid injections to manage chronic lower back pain.
Reliability of quantitative echocardiography in adult sheep and goats (2012)
Journal Article
Background Echocardiography is a non-invasive method for assessment of the ovine and caprine heart. Complete reference ranges for cardiac dimensions and time indices for both species are not currently available and reliability of these measurements... Read More about Reliability of quantitative echocardiography in adult sheep and goats.
Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in acute Myeloid Leukaemia (2012)
Journal Article
Background The CD34+CD38- subset of AML cells is enriched for resistance to current chemotherapeutic agents and considered to contribute to disease progression and relapse in Acute Myeloid Leukaemia (AML) patients following initial treatment. Met... Read More about Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in acute Myeloid Leukaemia.
Perceptual learning reconfigures the effects of visual adaptation (2012)
Journal Article
Our sensory experiences over a range of different timescales shape our perception of the environment. Two particularly striking short-term forms of plasticity with manifestly different time courses and perceptual consequences are those caused by visu... Read More about Perceptual learning reconfigures the effects of visual adaptation.
Cognitive control over motor output in Tourette syndrome (2012)
Journal Article
Tourette syndrome [TS] is a neurodevelopmental disorder characterised by chronic vocal and motor tics. TS has been associated with dysfunctional cognitive (inhibitory) control of behaviour, however the evidence for this, beyond the occurrence of tics... Read More about Cognitive control over motor output in Tourette syndrome.
WNT/?-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma (2012)
Journal Article
Background: Medulloblastoma is the most common malignant childhood brain tumour. Aberrant activation of the WNT/β-catenin pathway occurs in approximately 25% of medulloblastomas. However, its role in medulloblastoma pathogenesis is not understood.... Read More about WNT/?-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma.
Mapping the laminin receptor binding domains of Neisseria meningitidis PorA and Haemophilus influenzae OmpP2 (2012)
Journal Article
Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae are major bacterial agents of meningitis. They each bind the 37/67-kDa laminin receptor (LamR) via the surface protein adhesins: meningococcal PilQ and PorA, H. influenzae Om... Read More about Mapping the laminin receptor binding domains of Neisseria meningitidis PorA and Haemophilus influenzae OmpP2.