All Outputs (235)

Powered by imagination: nanobots at the Science Photo Library (2008)
Journal Article

Developing novel anthelmintics from plant cysteine proteinases (2008)
Journal Article

Intestinal helminth infections of livestock and humans are predominantly controlled by treatment with three classes of synthetic drugs, but some livestock nematodes have now developed resistance to all three classes and there are signs that human hoo... Read More about Developing novel anthelmintics from plant cysteine proteinases.

An Immune Inspired Approach to Anomaly Detection (2008)
Book Chapter

The immune system provides a rich metaphor for computer security: anomaly detection that works in nature should work for machines. However, early artificial immune system approaches for computer security had only limited success. Arguably, this was d... Read More about An Immune Inspired Approach to Anomaly Detection.

Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke (2008)
Journal Article

Background: Recurrent stroke is a frequent, disabling event after ischemic stroke. This study compared the efficacy and safety of two antiplatelet regimens — aspirin plus extended release dipyridamole (ASA–ERDP) versus clopidogrel. Methods: In this... Read More about Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke.

Roots/Routes (2008)
Journal Article

This narrative and poetic rendering acts as an articulation of a journey of many routes. It is a storying of critical research issues and events as performances of lived experience. It is a métissage of hybrid, but interrelated, themes that find cohe... Read More about Roots/Routes.

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease (2008)
Journal Article

Following recent success in genome-wide association studies, a critical focus of human genetics is to understand how genetic variation at implicated loci influences cellular and disease processes. Crohn's disease (CD) is associated with SNPs around I... Read More about Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease.

Associations between elevated atmospheric temperature and human mortality: A critical review of the literature (2008)
Journal Article

The effects of the anomalously warm European summer of 2003 highlighted the importance of understanding the relationship between elevated atmospheric temperature and human mortality. This review is an extension of the brief evidence examining this re... Read More about Associations between elevated atmospheric temperature and human mortality: A critical review of the literature.

Oxidative stability of sunflower oil bodies (2008)
Journal Article

This study investigates the oxidative stability of sunflower oil body suspensions (10 wt-% lipid). Two washed suspensions of oil bodies were evaluated over 8 days at three temperatures (5, 25 and 45 °C) against three comparable sunflower oil emulsion... Read More about Oxidative stability of sunflower oil bodies.

The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors (2008)
Journal Article

The PRH (proline-rich homeodomain) [also known as Hex (haematopoietically expressed homeobox)] protein is a transcription factor that functions as an important regulator of vertebrate development and many other processes in the adult including haemat... Read More about The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors.

General practitioners' views on reattribution for patients with medically unexplained symptoms: a questionnaire and qualitative study (2008)
Journal Article

Background: The successful introduction of new methods for managing medically unexplained symptoms in primary care is dependent to a large degree on the attitudes, experiences and expectations of practitioners. As part of an exploratory randomised... Read More about General practitioners' views on reattribution for patients with medically unexplained symptoms: a questionnaire and qualitative study.

Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma (2008)
Journal Article

Beyond Point Charges: Dynamic Polarization from Neural Net Predicted Multipole Moments (2008)
Journal Article

Intramolecular polarization is the change to the electron density of a given atom upon variation in the positions of the neighboring atoms. We express the electron density in terms of multipole moments. Using glycine and N-methylacetamide (NMA) as pi... Read More about Beyond Point Charges: Dynamic Polarization from Neural Net Predicted Multipole Moments.

DNA wrapping and distortion by an oligomeric homeodomain protein (2008)
Journal Article

Many transcription factors alter DNA or chromatin structure. Changes in chromatin structure are often brought about by the recruitment of chromatin-binding proteins, chromatin-modifying proteins, or other transcription co-activator or co-repressor pr... Read More about DNA wrapping and distortion by an oligomeric homeodomain protein.

Centrifugal propagation of motion adaptation effects across visual space (2008)
Journal Article

Perceptual distortions induced by adaptation (aftereffects) arise through selective changes in the response properties of discrete subpopulations of neurons tuned to particular image features at the adapted spatial location. The systematic and well-d... Read More about Centrifugal propagation of motion adaptation effects across visual space.

A multiproxy palaeolimnological investigation of Holocene environmental change, between c. 10 700 and 7200 years BP, at Holebudalen, southern Norway (2008)
Journal Article

Geochemical analyses (x-ray fluorescence, δ13C and C/N ratios) were used to reconstruct early Holocene environments (between 10685 and 7260 cal. yr BP) at a small lake near Holebudalen, southern Norway. Results show a period of increasing stability,... Read More about A multiproxy palaeolimnological investigation of Holocene environmental change, between c. 10 700 and 7200 years BP, at Holebudalen, southern Norway.

Self-esteem, shyness, and sociability in adolescents with specific language impairment (SLI) (2008)
Journal Article

Purpose: To determine if lower global self-esteem, shyness and low sociability are outcomes associated with SLI in adolescence. Possible concurrent predictive relationships and gender differences were also examined. Method: Fifty-four adolescents wit... Read More about Self-esteem, shyness, and sociability in adolescents with specific language impairment (SLI).

A two-fluid model for tissue growth within a dynamic flow environment (2008)
Journal Article

We study the growth of a tissue construct in a perfusion bioreactor, focussing on its response to the mechanical environment. The bioreactor system is modelled as a two-dimensional channel containing a tissue construct through which a flow of culture... Read More about A two-fluid model for tissue growth within a dynamic flow environment.

Use of ordinal outcomes in vascular prevention trials: comparison with binary outcomes in published trials (2008)
Journal Article

Background and Purpose—Vascular prevention trials mostly count “yes/no” (binary) outcome events, eg, stroke/no stroke. Analysis of ordered categorical vascular events (eg, fatal stroke/nonfatal stroke/no stroke) is clinically relevant and could be... Read More about Use of ordinal outcomes in vascular prevention trials: comparison with binary outcomes in published trials.

Computer-mediated infertility support groups: An exploratory study of online experiences (2008)
Journal Article

Objective: Over recent years the Internet has become an increasingly popular source of support and information for infertility, with a growing number of online support groups now available to individuals affected by fertility problems. The aims of th... Read More about Computer-mediated infertility support groups: An exploratory study of online experiences.

Ordinal reanalysis of the SHEP Trial (2008)
Journal Article